云南高校图书馆联盟文献共享服务平台- ANTITUMOR

ANTITUMOR: 作品数：470被引量：1206H指数：15; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：明艳林陈良华刘韶松齐宪荣李润涛更多>>; 相关机构：北京大学天津医科大学中国药科大学福建省亚热带植物研究所更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

Antitumor Effect and Molecular Mechanism of Ophiopogonin B: 《Plant Diseases and Pests》2023年第3期27-29,36,共4页Jingchao WANG Mingxinzhi WANG Hai CHEN Quan QUAN Xichun HUANG Chenghao JIN; Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16);Innovation and Entrepreneurship Training Program for College Students in Heilongjiang Province(202210223048).; Ophiopogonin B is a kind of saponin active substance extracted and purified from Ophiopogon japonicus,and plays an antitumor role by inhibiting cancer cell adhesion,invasion and proliferation,and inducing tumor cell a...; 关键词：Ophiopogonin B ANTITUMOR Cell proliferation APOPTOSIS

Chaetocin:a review of its anticancer potential and mechanisms被引量：3: 《中国药理学与毒理学杂志》2021年第10期731-731,共1页JIANG Hang-yu LI Yu-qi XIANG Xiao-cong TANG Zhi-li LIU Kang SU Qiang ZHANG Xiao-fen LI Lin; Chaetocin is a natural metabolite product with various biological activities and pharmacological functions isolated from Chaetomium species fungi belonging to the thiodiketopyrazines.Numerous studies have demonstrated...; 关键词：chaetocin ANTITUMOR APOPTOSIS signalling pathway

Pharmacological Mechanism of Isoliquiritigenin Antitumor: 《Medicinal Plant》2019年第1期17-18,共2页Hui XUE Jiaru WANG Wanting XU Yi ZHANG Yinghua LUO Chenghao JIN; Supported by Multigrain Production and Processing Characteristic Discipline Construction Project;the Postdoctoral Scientific Research Foundation of Heilongjiang Province of China(LBH-Q13132);National Key Research and Development Plan(2017YFD0401203); Isoliquiritigenin could play an antitumor role by inhibiting proliferation of tumor cells, inducing apoptosis of tumor cells and resisting neovascularity. In this paper, antitumor activity and mechanism of isoliquirit...; 关键词：ISOLIQUIRITIGENIN ANTITUMOR ACTIVITY CELL PROLIFERATION APOPTOSIS

Chinese Medicine Formula “Shenqi San” Extract Inhibits Proliferation of Human Lung Adenocarcinoma A549 Cells via Inducing Apoptosis被引量：4: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第5期766-771,共6页夏雨施璐艾中柱张德忠刘焱文尤朋涛; supported by grants from Doctoral Scientific Research Foundation of Hubei University of Chinese Medicine(No.5114-000912);Hubei University of Chinese Medicine Foundation For Young Scholar(No.5112-0007); The main purpose of this study was to investigate the active components of the Chinese medicine formula Shenqi San（SS） by high performance liquid chromatography with diode array detector and electrospray ionization-...; 关键词：chloroform extraction of Shenqi San ANTITUMOR mechanism APOPTOSIS pathway

Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells被引量：6: 《Acta Pharmacologica Sinica》2016年第11期1481-1489,共9页Shao XIE Hui JIANG Xiao-wen ZHAI Fan WEI Shu-dong WANG Jian DING Yi CHEN; This study was supported by a grant from the National Natural Science Foundation of China （81521005） and the National Basic Research Program of China （2013CB932503）.; Aim： LS-007 is a CDK inhibitor, which exhibits potent antitumor activity against chronic lymphocytic leukemia and ovarian cancer cells. In this study, we further evaluated the antitumor activity of LS-007 alone and i...; 关键词：acute leukemia CDK9 LS-007 ABT-199 APOPTOSIS drug synergism

Antitumor Activities and Apoptosis-regulated Mechanisms of Fermented Wheat Germ Extract in the Transplantation Tumor Model of Human HT-29 Cells in Nude Mice被引量：4: 《Biomedical and Environmental Sciences》2015年第10期718-727,共10页ZHANG Jia Yan XIAO Xiang DONG Ying WU Jing ZHOU Xing Hua; supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions and the Industry-academic Joint Technological Innovations Funded Project of Jiangsu Province(BY2012172); Objective A subcutaneous transplantation tumor model of human HT-29 cells in nude mice was established to evaluate anticarcinogenic activities, and the apoptosis-regulated mechanism effect of aqueous extract of fermen...; 关键词：Fermented wheat germ extract Nude mice ANTITUMOR APOPTOSIS Western blot Human HT-29 cells

Synthesis and Antitumor Activity of a New 7-Azaindole Derivative: 《Chemical Research in Chinese Universities》2014年第3期420-424,共5页ZHANG Peng SUI Dayun XU Huali SUN Weilun YU Xiaofeng QU Shaochun HU Jianbing WU Yi WANG Yingshi; We designed and synthesized a 7-azaindole derivative（TH1082）, which was characterized by 1^H NMR and 13^C-NMR. We investigated its antitumor effects on human melanoma A375 cells, human liver cancer SMMC cells and hu...; 关键词：7-Azaindole ANTITUMOR APOPTOSIS

CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells被引量：1: 《Acta Pharmacologica Sinica》2013年第1期146-156,共11页Ewa AUGUSTIN Barbara BOROWA-MAZGAJ Agnieszka KIKULSKA Milena KORDALEWSKA Monika PAWLOWSKA; Aim： To examine how the higher expression level of CYP3A4 isoenzyme influenced the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in Chinese hamster ovary （CliO） cells. Methods： Three CliO cell...; 关键词：APOPTOSIS triazoloacridinones C-1305 CHO cells CYP3A4 cellular response APOPTOSIS NECROSIS SENESCENCE

Synthesis, Antitumor and Apoptosis Inducing Activities of Novel 5-Fluorouracil Derivatives of Rare Earth （Sm, Eu） Substituted Polyoxometalates被引量：3: 《Chinese Journal of Chemistry》2012年第7期1589-1593,共5页冯长根甘强刘霞何洪优; Two novel 5-fluorouracil derivatives of rare earth （Sm, Eu） substituted polyoxometalates, K9（C4H4FN2O2）2- Sm（PW11O39）2·11H2O （FSmPW） and KgH（C4H4FN2O2）Eu（PW11O39）2＊11 H2O （FEuPW） were synthesized and c...; 关键词：POLYOXOMETALATES rare earth HeLa HEPG-2 ANTITUMOR APOPTOSIS

Are isothiocyanates potential anti-cancer drugs？被引量：15: 《Acta Pharmacologica Sinica》2009年第5期501-512,共12页Xiang WU Qing-hua ZHOU Ke XU; Acknowledgements Research in the authors＇ laboratory is supported in part by the National Natural Science Foundation of China （No 30873035） and the Key Project of the Foundation of Tianjin High Education Commission （No ZD200714）.; Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic, display anticarcinogenic activity beca...; 关键词：ISOTHIOCYANATE CHEMOPREVENTION anticarcinogenic ANTITUMOR APOPTOSIS cell

ANTITUMOR