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作品数：25被引量：40H指数：3
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The DEAD-box RNA helicase ZmRH48 is required for the splicing of multiple mitochondrial introns,mitochondrial complex biosynthesis,and seed development in maize被引量：1
《Journal of Integrative Plant Biology》2023年第11期2456-2468,共13页Yan-Zhuo Yang Shuo Ding Xin-Yuan Liu Chunhui Xu Feng Sun Bao-Cai Tan 
supported by the National Natural Science Foundation of China (Project Nos.32072126 and 32230075);the Shandong Provincial Natural Science Foundation (Project No.ZR2019MC005)。
RNA helicases participate in nearly all aspects of RNA metabolism by rearranging RNAs or RNA–protein complexes in an adenosine triphosphatedependent manner.Due to the large RNA helicase families in plants,the precise...
关键词：intron splicing MAIZE mitochondria RNA helicase seed development ZmRH48 
The spliceophilin CYP18-2 is mainly involved in the splicing of retained introns under heat stress in Arabidopsis
《Journal of Integrative Plant Biology》2023年第5期1113-1133,共21页Areum Lee Hyun Ji Park Seung Hee Jo Haemyeong Jung Hyun-Soon Kim Hyo-Jun Lee Youn-Sung Kim Choonkyun Jung Hye Sun Cho 
funded by the New Breeding Technology program(no,PJ01686202);the National Research Foundation of Korea(NRF;No.2022R1A2B5B02002008);Research Initiative Programs of the Korea Research Institute of Bioscience and Biotechnology(KRIBB;No.5372322)grants to H.C.
Peptidyl-prolyl isomerase-like 1(PPIL1)is associated with the human spliceosome complex.However,its function in pre-mRNA splicing remains unclear.In this study,we show that Arabidopsis thaliana CYCLOPHILIN 18-2(AtCYP1...
关键词：alternative splicing CYP18-2 HSFA2-Ⅲ intron retention spliceophilin spliceosome complex B~(ACT) THERMOTOLERANCE 
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration被引量：1
《Protein & Cell》2023年第5期318-336,共19页Dawei Meng Qian Zheng Xue Zhang Xuejiao Piao Li Luo Yichang Jia 
the Tsinghua-Peking Joint Center for Life Sciences,the Thousand-Talent Young Investigator Program,the IDG/McGovern Institute for Brain Research,the National Natural Science Foundation of China(81371361,92049114,31571097,82101495);The Beijing Municipal Science&Technology Commission(Z181100001518001,Z161100000216154);National Key R&D Program(2017YFC0110205);the Institute for Guo Qiang,Tsinghua University。
Emerging evidence suggests that intron-detaining transcripts(IDTs)are a nucleus-detained and polyadenylated mRNA pool for cell to quickly and effectively respond to environmental stimuli and stress.However,the underly...
关键词：SNIP1 RNPS1 SPLICEOSOME detained intron NEURODEGENERATION 
Plant Intron-Splicing Efficiency Database(PISE):exploring splicing of~1,650,000 introns in Arabidopsis,maize,rice,and soybean from~57,000 public RNA-seq libraries
《Science China(Life Sciences)》2023年第3期602-611,共10页Hong Zhang Jinbu Jia Jixian Zhai 
supported by the National Key R&D Program of China(2019YFA0903903);the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2016ZT06S172);the Shenzhen Sci-Tech Fund(KYTDPT20181011104005);the Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes(2019KSYS006);the Stable Support Plan Program of Shenzhen Natural Science Fund(20200925153345004);supported by the National Natural Science Foundation of China(32100444);the Shenzhen Fundamental Research Program(JCYJ20210324105202007)。
Intron retention is the most common alternative splicing event in plants and plays a crucial role in the responses of plants to environmental signals.Despite a large number of RNA-seq libraries from different treatmen...
关键词：SPLICING RNA-SEQ PLANT DATABASE 
“Too Soon on Earth”: A Biophilosophical Model of Schizophrenia. Some Implications for Humanoid Robots
《Advances in Bioscience and Biotechnology》2023年第1期34-47,共14页Bernhard J. Mitterauer 
This paper presents a new explanatory model for schizophrenia based upon philosophical, molecular and neurobiological hypotheses as well as on years of experience in observing and treating these patients. To start wit...
关键词：Non-Splicing of Introns Chimeric Glial Receptors Loss of Glial Boundary Setting Disordered Mediation Loss of Ego-Boundaries SCHIZOPHRENIA Evolutionary Potency Delusional Robots 
The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group Ⅱ introns in Arabidopsis chloroplasts被引量：1
《Journal of Integrative Plant Biology》2021年第11期1952-1966,共15页Li Zhang Jingli Chen Liqun Zhang Ying Wei Yajuan Li Xinyun Xu Hui Wu Zhong‐Nan Yang Jirong Huang Fenhong Hu Weihua Huang Yong‐Lan Cui 
This study was supported by the National Natural Science Foundation of China(31100180,31470337,31570231);Shanghai Natural Science Foundation(18ZR1428200);The Fund of Innovation Program of Shanghai Municipal Education Commission(2021-01-07-00-02-E00117);Shanghai Engineering Research Center of Plant Germplasm Resources(17DZ2252700)。
Chloroplast biogenesis requires the coordinated expression of chloroplast and nuclear genes.Here, we show that EMB1270, a plastid-localized pentatricopeptide repeat(PPR) protein, is required for chloroplast biogenesis...
关键词：Arabidopsis thaliana CRM Family Member 2 CHLOROPLAST EMB1270 intron splicing pentatricopeptide repeat protein 
High-efficiencygenomeediting in plants mediated by a Cas9 gene containing multiple introns被引量：3
《Plant Communications》2021年第2期63-77,共15页Ramona Grützner Patrick Martin Claudia Horn Samuel Mortensen Erin J.Cram Carolyn W.T.Lee-Parsons Johannes Stuttmann Sylvestre Marillonnet 
supported by core funding of the IPB;supported by grant STU642-1/1(DFG/GRC,Deutsche Forschungsgemeinschaft);supported by the National Science Foundation MCB award 1516371 to C.L.-P.and E.C.
The recent discovery of the mode of action of the CRISPR/Cas9 systemhas provided biologists with a useful tool for generating site-specific mutations in genes of interest.In plants,site-targeted mutations are usually ...
关键词：CRISPR Cas9 targeted mutagenesis gene targeting 
Identification,development,and application of cross-species intron-spanning markers in lentil(Lens culinaris Medik.)
《The Crop Journal》2018年第3期299-305,共7页Debjyoti Sen Gupta Jitendra Kumara Sunanda Gupta Sonali Dubey Priyanka Gupta Narendra Pratap Singh Gaurav Sablok 
the Indian Council of Agricultural Research,New Delhi,India for research support;partially funded by the Department of Biotechnology,Government of India,New Delhi,India through a grant support(BT/PR10921/AG11/106/943/2014)
Lentil(Lens culinaris Medik) is one of the most important food legumes in the world. The use in lentil of molecular marker-assisted breeding is limited, owing to the low availability of polymorphic markers. In the pre...
关键词：Allele diversity CROSS-SPECIES Genotypes INTRONS LENTIL Molecular markers 
Engineering Introns to Express RNA Guides for Cas9- and Cpfl-Mediated Multiplex Genome Editing被引量：15
《Molecular Plant》2018年第4期542-552,共11页Dan Ding Kaiyuan Chen Yuedan Chen Hong Li Kabin Xie 
This work was supported by the National Transgenic Science and Technology Program （2016ZX08010-002）, the National Natural Science Foundation of China （31571374 and 31622047）, and Fundamental Research Funds for the Central Universities （2662015PY212） to K.X.
The clustered regularly interspaced short palindromic repeat （CRISPR） system has emerged as the revolu- tionary platform for DNA targeting. This system uses a site-specific RNA guide to direct a CRISPR effector （e....
关键词：CRISPR INTRON Cas9 Cpfl multiplex 
Origin and evolutionary implications of introns from analysis of cellulose synthase gene
《Journal of Systematics and Evolution》2017年第2期142-148,共7页Punit Bhattachan Bo Dong 
Spliceosomal introns are present in diverse eukaryotic but not prokaryotic genes. However, their evolutionary origin is still arguable. Here, we address this question through an analysis of the cellulose synthase gene...
关键词：cellulose synthase EVOLUTION INTRONS urochordate. 
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