Supported by National Natural Science Foundation of China(82003683);Fundamental Research Funds for the Central Universities of Southwest Minzu University(2021105)。
[Objectives]The paper was to prepare immunoadjuvant nanoparticles with good photothermal conversion efficiency and to achieve the synergistic antitumor effect of phototherapy and immunotherapy.[Methods]Poly(lactic-co-...
the National Natural Science Foundation of China(32000999,81925020 and 81630051);the Key Project of Tianjin Natural Science Foundation(19JCZDJC34100);Open Project of State Key Laboratory of Oral Diseases(SKLOD2021OF07).
The conventional immunoadjuvants in vaccine have weak effect on stimulating antigen presentation and activating anti-tumor immunity.Unexpectedly,we discovered that non-pathogenic Sendai virus(SeV)could activate antige...
supported by grants from the Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Education,Science and Technology(2018R1A5A2024181,2020R1A2C2010098).
Nanovaccines are used as delivery platforms for antigens and adjuvants, which activate antigen-presenting cells (APCs) and enhance anticancer immune responses.1,2 Researchers have recently developed a self-assembled n...
This work was supported by grants from the National Natural Science Foundation of China,China(21904145,81972019 and 31700150);China Postdoctoral Science Foundation,China(2018M633273);Chen Jingyu team of Sanming Project of Medicine in Shenzhen,China(SZSM201812058);Guangdong Provincial Science and Technology Plan project,China(No.2017B030314108).
Immunotherapy assays using immunoadjuvants and tumor antigens could greatly increase the survival rates of patients with malignant tumors.As effective carriers,metal-organic frameworks(MOFs)have been widely utilized i...
supported in part by the US National Institutes of Health(P20 PR016478 from the INBRE Program of the National Center for Research Resources)
Treatment of metastatic cancer remains a great challenge and needs novel approaches.Combining a selective photothermal therapy with an active immunological stimulation,laser immunotherapy(LIT) was developed to induce ...
supported in part by a grant from the US National Institutes of Health(P20 RR016478 from the INBRE Program of the National Center for Research Resources).
Metastasis to distant sites is a severe treatment challenge and a major cause of death for breast cancer patients.Laser immunotherapy(LIT)is a novel technique,combining a selective photothermal therapy with local appl...
This work was supported by a grant from the National Natural Science Foundation of China(No.30300302)
The mip gene of Legionella pneumophila and the ctxB gene of Vibrio cholerae were amplified by PCR respectively.The amplified cDNA was ligated to the pcDNA3.1(+)vector.The recombinant plasmids pcDNA3,1-mip and pcDNA3.1...
Objective To develop an efficient expression, purification system of recombinant Escherichia coli heat labile enterotoxin B subunit (rLTB) and study its activity against mucosal immunoadjuvant by nasal immunization ...