In a report published in Cell on January 6,a team of CAS scientists led by Dr.LIU Guanghui and Dr.QU Jing at the Institute of Zoology and Dr.ZHANG Weiqi at the Beijing Institute of Genomics discovered a surprising con...
supported by National Natural Science Foundation of China(31922001)
Retroviruses exclusively infect vertebrates,causing a variety of diseases.The replication of retroviruses requires reverse transcription and integration into host genomes.When infecting germline cells,retroviruses bec...
This work was supported by the Soonchunhyang University Research Fund.
Retroviruses are a large group of infectious agents with similar virion structures and replication mechanisms.AIDS,cancer,neurologic disorders,and other clinical conditions can all be fatal due to retrovirus infection...
supported by Sichuan Province Department of Health(Grant Project:130188)
Objective:To study the expression of TRPC6 among prostate cancer cells,establish high expression cell lines of TRPC6,and to provide potential cell mode for prostate cancer oncogenesis and development.Methods:Occurrenc...
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. In the past few decades, many efforts have been made to improve the prognosis of GBM, however, with limited success. Many ...
National Natural Science Foundation of China(81101245,30970162);The Fundamental Research Funds for the Central Universities(65011871);National Training Programs of Innovation for Undergraduates(111005505)
The cellular protein tetherin tethers the HIV-1 viral particles on the cellular membrane to inhibit the replication of HIV-1. However, the HIV-1 accessory protein Vpu counteracts the antiviral function of tetherin. In...
The Chinese National Natural Science Foundation(No.30960271 and No.31160493);Inner Mongolia technological innovation fund (20101808);the Fund of innovation research team(NDPYTD2010-6)
Endogenous beta retroviruses (enJSRV) are highly homologous with Jaagsiekte sheep retrovirus (exJSRV),this exogenous retrovirus is the aetiological agent of ovine pulmonary adenocarcinoma (OPA). The aim of this study ...
Analysis of the frequencies of chromosomes carrying various classes of porcine endogenous retroviruses (PERVs) and combinations of these classes was performed in the swine species Sus scrofa L. by using maps construct...
A series of retroviral vectors encoding human mdrl gene alone as well as in combination with either human mgmt gene or human mutant Ser31-dftfrgene are engineered. The resultant retroviruses are used to transduce huma...