云南高校图书馆联盟文献共享服务平台- NEUREGULIN-1

NEUREGULIN-1: 作品数：53被引量：124H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：冯灵美宋耀明刘超赵炜疆蔡季平更多>>; 相关机构：复旦大学广西医科大学第二军医大学复旦大学上海医学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金广西研究生教育创新计划更多>>

Emerging role of neuregulin-1beta1 in pathogenesis and progression of multiple sclerosis: 《Neural Regeneration Research》2023年第1期133-134,共2页Seyyed Mohyeddin Ziaee Soheila Karimi-Abdolrezaee; supported by a University of Manitoba Graduate Fellowship;Graduate Enhancement of Tricouncil Supplement (GETS);Hillary Kaufman Lerner Memorial Funds;supported by the grants from Multiple Sclerosis Society of Canada (EGDI-2936, EGDI-3742);the Canadian Institute of Health Research (133721 and 156218); Multiple sclerosis(MS)is a chronic immune-mediated disorder of the central nervous system(CNS)that causes focal demyelinating lesions,followed by axonal and neuronal degeneration.Several genetic and environmental fact...; 关键词：PATHOGENESIS SCLEROSIS DEGENERATION

Neuregulin-1对过氧化氢诱导的小鼠骨髓间充质干细胞衰老的影响: 《广西医科大学学报》2021年第5期864-870,共7页颜池张天蓉黄伟强; 国家自然科学基金资助项目(No.81760415;No.81960056);广西研究生教育创新计划资助项目(No.YCSW2020114);广西医疗卫生适宜技术研究与开发项目(No.S201518)。; 目的:探讨Neuregulin-1(NRG-1)对过氧化氢(H2O2)诱导的小鼠骨髓间充质干细胞(BMSCs)衰老的影响。方法:用H2O2诱导小鼠BMSCs衰老模型,将BMSCs分为对照组、H2O2组、H2O2+NRG-1组。采用CCK8检测细胞存活率,β-半乳糖苷酶染色法检测细胞衰老...; 关键词：骨髓间充质干细胞 NEUREGULIN-1 细胞衰老

人参皂苷Rb3通过Neuregulin-1/ErbB信号通路对心肌梗死大鼠VE-cadherin,NRG-1,ErbB2,ErbB4表达的影响被引量：7: 《中国循证心血管医学杂志》2019年第2期195-199,共5页韩凌张晶晶秦立; 河南省科学技术成果(9412015J0308); 目的观察人参皂苷Rb3通过Neuregulin-1/ErbB信号通路对心肌梗死大鼠VE-cadherin,NRG-1,Erb B2,Erb B4表达的影响。方法 60只大鼠随机分为Sham组、Model组、G-Rb3-L组(10 mg/kg)、G-Rb3-M组(20 mg/kg)、G-Rb3-H组(40 mg/kg)及阳性药物组...; 关键词：人参皂苷RB3 心肌梗死 NRG-1/ErbB信号通路 VE-CADHERIN

Neuregulin-1及其受体ErbB在中枢神经系统损伤修复中作用的研究进展被引量：2: 《神经解剖学杂志》2019年第1期83-87,共5页王艳雪李坪张歆悦吴海鹰; 国家自然科学基金资助项目(31100769);云南省医疗卫生内设研究机构项目(2017NS065);云南省哲学社会规划项目(YB2016031); 神经调节蛋白-1(NRG-1)是一类包含表皮生长因子样结构域,在神经组织中发挥着多种生物学效应的营养因子。在神经损伤时,NRG-1的作用涉及神经元迁移、轴突生长、髓鞘和突触的形成,以及促进神经再生,近年来受到越来越多的关注,文中将对NRG-...; 关键词：神经调节蛋白-1 ErbB受体中枢神经系统损伤

Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model被引量：8: 《Neural Regeneration Research》2017年第11期1905-1910,共6页Xin Lai Liang Zhong Hai-xia Fu Song Dang Xin Wang Ning Zhang Gao-ke Feng Zi-qiang Liu Xi Wang Long Wang; supported by a grant from the National Key Basic Research Development Program,the“973”Program,No.2012CB518604;the National Natural Science Foundation of China,No.81260052;the Natural Science Foundation of Hubei Province,No.2014CKB497,2014BKB075,and 2015BKA339;the Natural Science Foundation of Henan Province of China,No.201602262; Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction （MI）. Increasing evidence indicates that neuregulin-1 （NRG-1） improves cardiac function following ...; 关键词：nerve remodeling myocardial infarction NEUREGULIN-1 sympathetic nerve vagus nerve animal model real-time PCR westernblot assay cardiac function ECHOCARDIOGRAPHY

Neuregulin-1:a novel regulator of glial response in spinal cord injury: 《Neural Regeneration Research》2017年第10期1616-1617,共2页Hardeep Kataria Soheila Karimi-Abdolrezaee; supported by grants awarded to SKA from the Canadian Institutes of Health Research(CIHR,No.MOP 133721);the Canadian Paraplegic Association of Manitoba,and the Manitoba Paraplegic Foundation;supported by a fellowship from Research Manitoba and Rick Hansen Institute; Spinal cord injury （SCI） results in a dysregulated microenvi- ronment that is largely driven by the immediate and robust response of resident astrocytes and microglia （Filous and Silver, 2016）.; 关键词：Neuregulin-1:a novel regulator of glial response in spinal cord injury SCI

Expression pattern of neuregulin-1 type Ⅲ during the development of the peripheral nervous system被引量：2: 《Neural Regeneration Research》2015年第1期65-70,共6页Liang-liang Huang Zhong-yang Liu Jing-hui Huang Zhuo-jing Luo; supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542206;the National Natural Science Foundation of China,No.81201389,30973052;Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China,No.IRT13051; Neuregulin-1 type Ⅲ is a key regulator in Schwann cell proliferation, committing to a myelinat- ing fate and regulating myelin sheath thickness. However, the expression pattern of neuregulin- 1 type III in the periph...; 关键词：nerve regeneration Schwann cells dorsal root ganglia myelin sheath neuregulin-1type Ⅲ peripheral nervous system quantitative real-time polymerase chain reaction western blot immunofluorescent staining postmyelinating rats NSFC grants neural regeneration

Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines被引量：1: 《World Journal of Cardiology》2014年第7期653-662,共10页Cecilia Vasti Cecilia M Hertig; Supported by National Research Council of Argentina,CONICET PIP N°0722; Neuregulin-1(NRG1)signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis,and it plays an essential role in maintaining the myocardial architecture during adulthood.The ty...; 关键词：Ventricular dilation CARDIOTOXICITY Erbb2 ERBB4 NEUREGULIN TRASTUZUMAB Doxorubicin

血清Neuregulin-1β浓度与血管生成因子浓度的相关性: 《广西医学》2014年第2期137-140,共4页陈林林桂春韦晓敏堵芳农勤玲; 国家自然科学基金资助项目(81160021);广西自然科学基金资助项目(GXNSFA018223); 目的探讨糖尿病(DM)和不稳定型心绞痛(UAP)患者血清Neuregulin-1β(NRG-1β)因子浓度与血清中5种血管生成因子的相关性。方法选择DM患者42例,UAP患者57例,健康体检者36例作为对照组。采用蛋白芯片方法检测各组血清NRG-1β、血管内皮生...; 关键词：糖尿病心绞痛 Neuregulin-1β 血管内皮生长因子血管形成蛋白-1

血清Neuregulin-1β在慢性心力衰竭患者中的表达及其诊断价值的研究被引量：1: 《临床合理用药杂志》2013年第8期1-3,共3页张慧英宋书凯韩百智董培康吕孝欣万荣; 目的检测慢性心力衰竭(CHF)患者外周血清Neuregulin-1β(NRG-1β)的表达水平,评价NRG-1β在CHF中的诊断价值及应用前景。方法采用酶联免疫吸附试验(ELISA)检测59例CHF患者(心衰组)和26例健康对照者(对照组)的NRG-1β、N末端B型利钠肽原(...; 关键词：Neuregulin-1β 心力衰竭慢性 N末端B型利钠肽原诊断价值

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