POLYMORPHISMS

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Interactions of Vitamin D Receptor Polymorphisms with Hypertriglyceridemia and Obesity in Chinese Individuals Susceptible to Hypertension and Diabetes Comorbidity
《Biomedical and Environmental Sciences》2023年第2期196-200,共5页SUN Hua Lei ZHAO Tong ZHANG Dong Dong FENG Ming Ming XU Ze HUANG Hao Yue ZHANG Luo Ya LI Wen Jie LI Xing DUAN Jia Yu LI Jia 
supported by grants from the National Natural Science Foundation of China[grant numbers 82003454,81903314,and 81872626];National Natural Science Foundation of Henan Province[grant number 222300420337];Chinese Nutrition Society-Bright Moon Seaweed Group Nutrition and Health Research Fund[grant number CNS-BMSG2020A63];Chinese Nutrition Society Zhendong National Physical Fitness and Health Research Fund[grant number CNS-ZD2019066];key R&D and promotion projects in Henan Province[grant numbers 212102310219,212102310110,and 202102310120];National Natural Science Foundation of China[grant number 81903314].
Hypertension(HTN)and type 2 diabetes mellitus(T2DM)are interconnected metabolic diseases[1,2]that considerably increase susceptibility to microvascular and macrovascular disorders.In many patients,HTN and diabetes com...
关键词：MORBIDITY inflammation diseases 
Association of VDR Polymorphisms and Gene-obesity Interaction with Type 2 Diabetes:A Case-control Study among Chinese Rural Population
《Biomedical and Environmental Sciences》2022年第11期1074-1078,共5页XU Ze ZHANG Dong Dong LIU Ya Ping ZHANG Yu Jing XUE Yuan GAO Jiao Jiao ZHAO Tong HUANG Hao Yue LI Wen Jie LI Xing 
funded by the National Natural Science Foundation of China[Grant no.81872626,82003454];Chinese Nutrition Society-Zhendong National Physical Fitness and Health Research Fund[Grant no.CNS-ZD2019066];Key R&D and promotion projects in Henan Province[212102310219 and 202102310120]。
In recent years,the prevalence of type 2 diabetes(T2D)has increased at an alarming rate,and the epidemic of T2D mellitus and its complications poses a major global health threat.Globally,the International Diabetes Fed...
关键词：DIABETES OBESITY MELLITUS 
Association between Polymorphisms in Telomere-Associated Protein Genes and the Cholinesterase Activity of Omethoate-Exposed Workers
《Biomedical and Environmental Sciences》2022年第5期448-452,共5页FAN Ya Hui LI Xin Ling LIU Xiao Hua GUO Zhi Feng YAN Meng Qing DUAN Xiao Ran MIAO Wen Bin WANG Wei 
supported by Programs for Science and Technology Development of Zhengzhou[131PPTGG376];the Outstanding Youth Grant of Zhengzhou University[1521329035]
Organophosphorus pesticides(OPs)are extensively used for their high efficiency,broad spectrum,and low residue.However,the health hazards caused by long-term,low-dose exposure to OPs are easily ignored.Omethoate is a l...
关键词：PESTICIDES China. RESIDUE 
Polymorphisms of the Vitamin D Receptor Gene and SexDifferential Associations with Lipid Profiles in Chinese Han Adults被引量：1
《Biomedical and Environmental Sciences》2022年第2期115-125,共11页CHEN Yan Mei XU Ping WANG Zhou Tian ZHU Yu Mei GONG Chun Mei HUANG Chang Hua LIU Xiao Li ZHOU Ji Chang 
supported by the National Natural Science Foundation of China[grant number 81973038];Science,Technology and Innovation Commission of Shenzhen Municipality,China[grant number JCYJ20200109142446804].
Objective To explore the association of single nucleotide polymorphisms(SNPs)of the vitamin D receptor gene(VDR)with circulating lipids considering gender differences.Methods Of the Han Chinese adults recruited from a...
关键词：Vitamin D Vitamin D receptor Gene polymorphism LIPID DYSLIPIDEMIA 
Association of miRNA-492 rs2289030 G>C and miRNA-938rs2505901 T>C Gene Polymorphisms with Biliary Atresia Susceptibility被引量：1
《Biomedical and Environmental Sciences》2021年第7期577-580,共4页SU Liang TIAN Yan FU Ming ZHANG Rui Zhong OU Xiu Fei XIA Hui Min LI Rui Zhuo 
supported by the Medical Science and Technology Research Foundation of Guangdong Province[No.2017A020214017]。
Biliary atresia(BA)is one of the most common and enigmatic forms of neonatal cholestasis and is characterized by inflammation and obstruction of extrahepatic bile ducts resulting in biliary cirrhosis,which occurs in 1...
关键词：RES alterations DIAGNOSIS 
Polymorphisms in CYP2R1 Gene Associated with Serum Vitamin D Levels and Status in a Chinese Rural Population被引量：1
《Biomedical and Environmental Sciences》2019年第7期550-553,共4页WANG Yan HAN Han WANG Jun SHEN Fang YU Fei WANG Ling YU Song Cheng ZHANG Dong Dong SUN Hua Lei XUE Yuan BA Yue WANG Chong Jian LI Wen Jie 
supported by the National Nature Science Foundation of China [grants number 81872626,81573151,U1204823,and 81573243];Science and Technology Foundation for Innovation Talent of Henan Province [No.154200510010]
Vitamin D, a fat-soluble vitamin and endocrine horm one, and it impacts various bone and extra-bone health, such as osteoporosis, diabetes, and cancer. The main circulating form of vitamin D is 25-hydroxyvitamin D [25...
关键词：POLYMORPHISMS CYP2R1 GENE SERUM VITAMIN D CHINESE RURAL Population 
Association between NFE2L2 Gene Polymorphisms and Noise-induced Hearing Loss in a Chinese Population被引量：2
《Biomedical and Environmental Sciences》2019年第6期465-470,共6页WANG Bo Shen XU Kai ZHANG Hong PU Yue Pu YIN Li Hong HAN Lei CHEN Lin WANG Ning ZHU Bao Li ZHANG Juan 
supported by Outstanding Medical Academic Leaders program of Jiangsu Province [LJ201130];Jiangsu Provincial Youth Medical Talent program [QNRC2016536];Six Talent Peaks Project in Jiangsu Province [WSW-017];Preventive Medicine Foundation of Jiangsu [Y2015049];The Fundamental Research Funds for the Central Universities [3225009404]
Occupatio nal n oise is among the most comm on risks associated with the wellbeing of employees. Occupational exposure to noise causes disabling hearing loss in 16% of adults worldwide.It has bee n ack no wledged that...
关键词：NFE2L2 GENE POLYMORPHISMS CHINESE POPULATION 
Association of Vitamin D Receptor Gene Polymorphisms with Metabolic Syndrome in Rural Areas of China被引量：1
《Biomedical and Environmental Sciences》2019年第4期304-308,共5页WANG Jun WANG Yan HAN Han WANG Teng SHEN Fang LI Wen Jie LI Xing 
supported by the National Nature Science Foundation of China [grants number 81872626,81573151,U1204823,and 81573243];Science and Technology Foundation for Innovation Talent of Henan Province [grants number 1542005 10010];Dietary Nutrition Research and Education Foundation of Danone [grants number DIC2013-06]
Metabolic Syndrome (MS) is a combination of multiple complex diseases, whose etiology is complicated and has many influencing factors Randomized controlled trials have shown that vitamin D supplementation could delay ...
关键词：VITAMIN D RECEPTOR GENE POLYMORPHISMS 
Significant Polymorphisms of Vitamin D Receptor Gene(rs2189480 and rs3847987) Related to the Risk of Type 2 Diabetes in Henan Rural Area被引量：1
《Biomedical and Environmental Sciences》2019年第1期58-62,共5页HAN Han ZHAO Ming Xu WANG Yan WANG Jun REN Bing Nan GE Hui Na WANG Teng SUN Bei Bei BA Yue LI Wen Jie 
supported by grants from the National Natural Science Foundation of China[81573151,81872626,and81573243];Science and Technology Foundation for Innovation Talent of Henan Province[154200510010];Dietary Nutrition Research and Education Foundation of Danone[DIC2013-06]
Type 2 diabetes mellitus (T2DM) accounts for 90% of all diabetes cases and results in severe complications. It is a multifactorial metabolic disorder that results from a combination of resistance to insulin action and...
关键词：VITAMIN D Type 2 diabetes MELLITUS (T2DM) INSULIN 
Association of CDKN2B-AS1 Polymorphisms with Premature Triple-vessel Coronary Disease and Their Sex Specificity in the Chinese Population被引量：4
《Biomedical and Environmental Sciences》2018年第11期787-796,共10页XU Jing Jing JIANG Lin XU Lian Jun GAO Zhan ZHAO Xue Yan ZHANG Yin SONG Ying LIU Ru SUN Kai GAO Run Lin XU Bo SONG Lei YUAN Jin Qing 
supported by funding from the CAMS Innovation Fund for Medical Sciences(CIFMS)[2016-I2M-1-002];National Basic Research Program of China [2010CB732601];National High Technology Research and Development Program of China [2015AA020407];National Natural Science Foundation of China [81470380]
Objective The aim of this study is to establish whether cyclin-dependent kinase inhibitor 2B antisense RNA 1(CDKN2 B-AS1) gene polymorphisms are associated with premature triple-vessel disease(PTVD). Methods Nine sing...
关键词：Premature triple-vessel disease Single-nucleotide polymorphism Risk 
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