POLYMORPHISMS

作品数：634被引量：2320H指数：17
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相关作者：王荣顾民韩志坚陶俊王子杰更多>>
相关机构：南京医科大学首都医科大学北京协和医院广西医科大学第一附属医院更多>>
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Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis
《World Journal of Gastroenterology》2025年第7期156-159,共4页Shi Li Yue Xi Xue-Ying Dong Wen-Bin Yuan Jing-Feng Tang Ce-Fan Zhou 
Supported by National Natural Science Foundation of China,No.32270768,No.82273970,No.32070726,and No.82370715;National Key R&D Program of China,No.2023YFC2507904;the Innovation Group Project of Hubei Province,No.2023AFA026.
Hepatitis B virus remains a major cause of cirrhosis and hepatocellular carcinoma,with genetic polymorphisms and mutations influencing immune responses and disease progression.Nguyen et al present novel findings on sp...
关键词：Hepatitis B virus Gene polymorphisms Multi-clustering analysis Genetic markers Personalized medicine Clinical implications 
Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution
《World Journal of Gastrointestinal Oncology》2025年第1期101-109,共9页Mariarosaria D'Amato Gennaro Iengo Nicola Massa Chiara Carlomagno 
BACKGROUND Fluoropyrimidines are metabolized in the liver by the enzyme dihydropyrimidine dehydrogenase(DPD),encoded by the DPYD gene.About 7%of the European population is a carrier of DPYD gene polymorphisms associat...
关键词：Dihydropyrimidine dehydrogenase DPYD polymorphisms FLUOROPYRIMIDINE Caucasian population Gastrointestinal cancers 
Nucleotide excision repair gene polymorphisms and hepatoblastoma susceptibility in Eastern Chinese children:A five-center case-control study
《Chinese Journal of Cancer Research》2024年第3期298-305,共8页Huimin Yin Xianqiang Wang Shouhua Zhang Shaohua He Wenli Zhang Hongting Lu Yizhen Wang Jing He Chunlei Zhou 
supported by grants from the Innovation and Cultivation Fund Project of the Seventh Medical Center,PLA General Hospital(No.QZX-2023-7);Postdoctoral Science Foundation of China(No.2021M691649);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Nucleotide excision repair(NER)plays a vital role in maintaining genome stability,and the effect of NER gene polymorphisms on hepatoblastoma susceptibility is still under investigation.This study aimed to ev...
关键词：Nucleotide excision repair POLYMORPHISMS HEPATOBLASTOMA SUSCEPTIBILITY 
Involvement of CD40 (rs1883832) and MAP3K14 (rs2074292) Genes Polymorphisms in Hepatitis B Virus Infection in Burkina Faso, West Africa
《Journal of Biosciences and Medicines》2023年第12期343-361,共14页Lassina Traore Nouhoun Nignan Sanata Kiemde Abdoul Rasmané Koumbem Sidnooma Véronique Zongo Minane Nafissa Triande Abdoul Karim Ouattara Marie Simone Traore Tegwindé Rébéca Compaore Tani Sagna Ina Marie Traore Albert Théophane Yonli Bolni Marius Nagalo Florencia Wendkuuni Djigma Jacques Simpore 
Introduction: Hepatic diseases comprise inflammations of the liver, which can originate from drug-induced, toxic, autoimmune sources and particularly hepatitis B and C virus infection. The outcome of the disease is li...
关键词：POLYMORPHISMS MAP3K14 CD40 HBV and Burkina Faso 
The moderating role of NTSR1 polymorphisms on personality and coping styles among breast cancer patients
《Psychosomatic Medicine Research》2023年第3期7-15,共9页Ran Hao Jin-Fan Zuo Meng Zhang Hao-Yu Jin Jie Hu Yi-Xin Qi 
This work was supported by the National Natural Science Foundation of China[grant number 72074067];S&T Program of Hebei[grant number 21377729D];Natural Science Foundation of Hebei Province[grant numbers H2020206483,H2021206289];Technical Innovative Youth Talents of Hebei Medical University[grant number TJSK202103];Young scientific and technological talents support program of Hebei Medical University[grant number CYCZ2021012].
Background:Some personality traits could be a predictor for coping styles.The objective of this investigation was to examine the correlation between personality traits and coping mechanisms in the context of gene regu...
关键词：PERSONALITY coping style single nucleotide polymorphism breast cancer 
Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival被引量：1
《Cancer Biology & Medicine》2023年第6期438-451,共14页Meizhi Du Yu Wang Jillian Vallis Matin Shariati Patrick S.Parfrey John R.Mclaughlin Peizhong Peter Wang Yun Zhu 
grants from the National Natural Science Foundation of China(Grant No.82003533);the CNS-ZD Tizhi and Health Fund(Grant No.CNS-ZD2020-82);funded by the Canadian Institutes of Health Research Team grant(Grant No.CIHR-CPT79845);Canadian Institutes of Health Research Team in Interdisciplinary Research on Colorectal Cancer Studentship(Grant No.205835);the National Cancer Institutes of Health under RFA#CA-08-502;cooperative agreements with members of the Colon Cancer Family Registry and principal investigators:Ontario Registry for Studies of Familial Colorectal Cancer(Grant No.U01 CA074783)。
Objective:Leptin(LEP)is an obesity-associated adipokine associated with tumor cell growth.We examined the relevance of genetic variants of LEP and leptin receptor(LEPR)to colorectal cancer(CRC)survival by using data f...
关键词：COLORECTAL CANCER INTAKE 
Association between the TP53 Arg72Pro Polymorphisms and Gastric Cancer Risk: An Updated Meta-Analysis and Re-Analysis of Systematic Meta-Analyses
《Advances in Lung Cancer》2023年第1期1-19,共19页Lili Huo Yuwei Wang Di Wang Jingyi Chen Changqing Yang Xiaofeng He 
Background: A latest Meta-analysis on TP53 Arg72Pro polymorphism with gastric cancer (GC) risk was published in 2015 including 20 literatures, while our study included 43 studies. Moreover, the results of previously p...
关键词：P53 Polymorphism Gastric Cancer META-ANALYSIS BFDP FPRP 
Association of ERCC1 and XPF polymorphisms with pediatric glioma susceptibility
《Chinese Medical Journal》2023年第6期746-748,共3页Yongping Chen Yuxiang Liao Xingyu Jia Huiran Lin Lei Miao Li Yuan Xiaokai Huang Jingying Zhou Jun Bian Zhenjian Zhuo 
supported by grants from the National Natural Science Foundation of China(No.81802346);the China Postdoctoral Science Foundation(Nos.2020T130132,2020M682668)
To the Editor:Glioma is a highly invasive and lethal heterogeneous disease caused by glial or precursor cell mutation.It accounts for about 50%of tumors in children and 80%of malignant tumors.[1]The nucleotide excisio...
关键词：ERCC1 XPF EXCISION 
Relationship between IKZF1 polymorphisms and the risk of acute lymphoblastic leukemia: a meta-analysis
《Oncology and Translational Medicine》2022年第5期217-225,共9页Sisi Wang Chuyang Lin Tingting Xi Yu Tong Jinlin Wu 
Supported by the National Key Project of Neonatal Children (No. 1311200003303);Grants from the Science and Technology Bureau of Sichuan Province (No. 2021YJ0211 to Jinlin Wu);Grants from the Health Planning Committee of Sichuan Province (No. 20PJ070 to Jinlin Wu)
Objective The aim of the study was to systematically evaluate the correlation between IKZF1 polymorphisms and the risk of acute lymphoblastic leukemia.Methods Computer databases including PubMed,EMBASE,and Web of Scie...
关键词：IKZF1 gene polymorphism acute lymphoblastic leukemia(ALL) META-ANALYSIS systematic reviews case-control study 
CASC15 Gene Polymorphisms and Glioma Susceptibility in Chinese Children
《Current Medical Science》2022年第4期797-802,共6页Hui-ran LIN Yong-ping CHEN Hui-tong CHEN Xiao-ping LIU Jing-ying ZHOU Xiao-kai HUANG Li YUAN Zhen-jian ZHUO 
funded by grants from the Natural Science FoundationofGuangdongProvince(No.2020A1515010188);the National Natural Science Foundation of China(Nos.81802346 and 81672496);the Science and Technology Project of Guangzhou(No.201804010042).
Objective:Gliomas are the most common tumors in the central nervous system.The cancer susceptibility candidate 15(CASC15)gene has been reported to be a susceptibility gene for several types of cancer.No studies have b...
关键词：cancer susceptibility candidate 15 POLYMORPHISMS GLIOMA SUSCEPTIBILITY Chinese 
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