SYNAPTOSOME

作品数:6被引量:6H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Virologica Sinica》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金广东省自然科学基金江苏省教育厅科研基金国家重点基础研究发展计划更多>>
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Synaptosome microRNAs:emerging synapse players in aging and Alzheimer’s disease被引量:3
《Neural Regeneration Research》2023年第6期1275-1276,共2页Subodh Kumar 
National Institute of Aging (NIA), National Institute of Health (NIH) for the funding the K99/R00 awards- K99AG065645 and R00AG065645 to SK
Synaptosome:Synapses are the most critical portion of neuron connections,necessary for cellular organization of the brain.Synapse integrity is uttermost important for healthy brain functioning.Any perturbation in the ...
关键词:ALZHEIMER DISEASES 
Tumor Necrosis Factor a Reduces SNAP29 Dependent Autolysosome Formation to Increase Prion Protein Level and Promote Tumor Cell Migration
《Virologica Sinica》2021年第3期458-475,共18页Huan Li Ren Wang Ze Yu Run Shi Jie Zhang Shanshan Gao Ming Shao Shuzhong Cui Zhenxing Gao Jiang Xu Man-Sun Sy Chaoyang Li 
supported by grants from the National Science Foundation of China (31670170 & 81560442);from MOST (2018YFA0507201);from the Natural Science Foundation of Guangdong Province (2017ZC0236)。
Tumor Necrosis Factor α(TNFα) is best known as a mediator of inflammation and immunity, and also plays important roles in tumor biology. However, the role of TNFα in tumor biology is complex and not completely unde...
关键词:Tumor necrosis factorα(TNFα) Prion protein Synaptosome associated protein 29(SNAP29) Autophagy Nuclear factor kappa B(NF-κB) Forkhead box P3(FOXP3) 
Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop被引量:1
《Neural Regeneration Research》2015年第6期925-931,共7页Ling-ling Shen Ming-liang Jiang Si-si Liu Min-chun Cai Zhong-qiu Hong Li-qing Lin Yan-yan Xing Gui-lin Chen Rui Pan Li-juan Yang Ying Xu Jun Dong 
supported by the National Natural Science Foundation of China,No.81171134 and 81471235;a grant from the Introducing Talents of Discipline to Universities,No.B14036;a grant from the College Students’Extracurricular Scientific Innovation and Entrepreneurial Activity Research Topic of Jinan University Challenge Cup,No.(2013)27 and (2014)16;a grant from the College Students’Extracurricular Scientific Innovation and Entrepreneurial Activity Research Topic of Jinan University in China,No.201410559079,1055914162 and CX14261;a grant from the National Basic Research Program of China(973 Program),No.2011CB707501;the Science and Technology Foundation of Guangdong Province in China,No.2010B030700016;the Natural Science Foundation of Guangdong Province in China,No.2014A030313360
Curcumin has been shown to significantly improve spatial memory impairment induced by HIV-1 gp 120 V3 in rats, but the electrophysiological mechanism remains unknown. Using extracellular microelectrode recording techn...
关键词:nerve regeneration CURCUMIN neurons HIV-1 gp l20 V3 loop plasticity HIV-associatedneurocognitive disorders output^input curve long-term potentiation excitatory postsynaptic potential paired-pulse facilitation Cd+ SYNAPTOSOME NSFC grants neural regeneration 
HDT-1, a new synthetic compound, inhibits glutamate release in rat cerebral cortex nerve terminals (synaptosomes)
《Acta Pharmacologica Sinica》2008年第11期1289-1295,共7页Su-jane WANG Shiu-huey CHOU Yuh-chi KUO Shang-shing Peter CHOU Woan-fang TZENG Jxh-yih LEU Rwei-fen S HUANG Yih-fong LIEW 
Aim: Excessive glutamate release has been proposed to be involved in the pathogenesis of several neurological diseases. In this study, we investigated the effect of HDT-1 (3, 4, 4a, 5, 8, 8a-hexahydro-6,7-dimethyl-...
关键词:isoquinoline alkaloid NEUROPROTECTION glutamate release voltage-dependent Ca^2+ channel SYNAPTOSOME cerebral cortex 
Effect of Propofol on Glutamate and γ-aminobutyric Acid Release from Rat Hippocampal Synaptosomes被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2005年第6期700-702,共3页尚游 姚尚龙 曾因明 刘红亮 曹君利 
ThisprojectwassupportedbyagrantfromtheFoundationofEducationCommissionofJiangsuProvince(No.KJS03084).
To investigate the effect of propofol on the release of glutamate and γ-aminobutyric acid (GABA) from rat hippocampal synatosomes, synaptosomes was made from hippocampus and incubated with artificial cerebrospinal ...
关键词:PROPOFOL HIPPOCAMPUS SYNAPTOSOME GLUTAMATE γ-aminobutyric acid 
Effects of Phenamiphos on Muscarinic Acetylcholine Receptor in the Brain Synaptosome in Rats and Its Mechanism
《Journal of Huazhong University of Science and Technology(Medical Sciences)》1994年第2期89-93,共5页孙黎 马谭庚 刘毓谷 
The studies were performed to investigate the mechanism of phenamiphos affecting muscarinic acetylcholine receptor (M-AchR) of the brain synaptosome in rats.The results showed that phenamiphos inhibited the binding of...
关键词:organophosporous insecticides acetylcholine receptor sulfhydryl group 
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