DITERPENOIDS

作品数:159被引量:213H指数:6
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相关领域:理学医药卫生更多>>
相关作者:皮晓雪杨蓉吴琼谢可辉付宏征更多>>
相关机构:中国科学院北京大学扬州大学中国医学科学院中国协和医科大学更多>>
相关期刊:《Progress in Natural Science:Materials International》《Petroleum Science》《Molecular Plant》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金国家教育部博士点基金更多>>
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Skeleton Rearranged and Oxygenated ent-Rosane Diterpenoids with Antiadipogenic Activity from Euphorbia milii
《Chinese Journal of Chemistry》2024年第24期3211-3218,共8页Qin-Qin Song Yue Guo Peng Sun Yao-Yue Fan Kai-Long Ji 
Financial support from the National Natural Science Foundation of China(No.82122062);the 145 Programs(XTBG-145)of Xishuangbanna Tropical Botanical Garden,Chinese Academy of Sciences(CAS);the Program of CAS Key Laboratory of Tropical Plant Resources and Sustainable Use(No.20228012802)is highly acknowledged.
Five unreported and oxygenated ent-rosane diterpenoids(ent-RDs),Euphomillanols A—E(1—5),were isolated from Euphorbia milii.Among them,compounds 1 and 2 are unprecedented 7/7/6-fused tricyclic 5,10-seco-ent-RDs and p...
关键词:ent-Rosane diterpenoids Euphorbia milii Structure elucidation Configuration determination Biosynthetic pathway hypothesis Oxidation Biological activity Antiadipogenic activity 
Natural Sesquiterpenoids, Diterpenoids, Sesterterpenoids, and Triterpenoids with Intriguing Structures from 2017 to 2022
《Chinese Journal of Chemistry》2023年第22期3115-3132,共18页Xiaotian Zhang Meijia Zheng Aimin Fu Qin Li Chunmei Chen Hucheng Zhu Yonghui Zhang 
This review covers the isolation,structural determination,plausible biosynthetic pathways,and biological activities of 166 natural terpenoids including 57 sesquiterpenoids,65 diterpenoids,15 sesterterpenoids,and 29 tr...
关键词:SESQUITERPENOIDS DITERPENOIDS Sesterterpenoids TRITERPENOIDS Structura scaffolds Biosynthetic pathways Structure elucidation Drug discovery 
cis-Clerodane Diterpenoids with Structural Diversity and Anti-inflammatory Activity from Tinospora crispa被引量:1
《Chinese Journal of Chemistry》2022年第24期2882-2892,I0002,共12页Jin-Qiu You Yi-Nan Liu Jun-Su Zhou Xin-Yu Sun Chun Lei Qing Mu Jing-Ya Li Ai-Jun Hou 
supported by the National Natural Science Foundation of China(No.22277074).
Twelve new cis-clerodane diterpenoids, designated as crispinoids A—L (1—12), together with three known analogues (13—15), were isolated from Tinospora crispa. Their structures were fully assigned by comprehensive s...
关键词:Natural products Structure elucidation Tinospora crispa ATP-citrate lyase Nuclear factor kappa B 
Highly Oxygenated Dimeric Grayanane Diterpenoids as Analgesics:TRPV1 and TRPA1 Dual Antagonists from Rhododendron molle被引量:3
《Chinese Journal of Chemistry》2022年第19期2285-2295,共11页Lang Huang Guijuan Zheng Yuanyuan Feng Pengfei Jin Biao Gao Hanqi Zhang Xiaomin Ma Junfei Zhou Guangmin Yao 
This work was supported by the Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2022-KF08);the Fund of Laboratory of Xinjiang Native Medicinal and Edible Plant Resource Chemistry(KSUZDSYS202101);the National Natural Science Foundation of China(22107033 and U1703109);the Traditional Chinese Medicine of Hubei Provincial Health Commission(ZY2021M056);the China Postdoctoral Science Foundation(2021M691152)。
Six highly oxygenated dimeric grayanane diterpenoids(1—6)including three new ones,bismollethers A—C(1—3),were isolated from the flowers of Rhododendron molle collected at Qichun,Hubei,China.The structures and relat...
关键词:Biological activity Dimeric grayanane diterpenoids Natural products Rhododendron molle(Ericaceae) Structure elucidation 
Kalihioxepanes A-G:Seven Kalihinene Diterpenoids from Marine Sponge Acanthella cavernosa Collected off the South China Sea被引量:1
《Chinese Journal of Chemistry》2022年第15期1785-1792,共8页Zhe Wang Xiao Han Guoping Liu Di Zhang Huiyue Hou Li Xiao Nicole J.de Voogd Xuli Tang Pinglin Li 
This work was supported by the National Natural Science Foundation of China(Nos.U2006204,41776136,2181101213,81991522,and 41876161)。
Comprehensive Summary Seven new kalihinene diterpenoids,kalihioxepanes A-G(1-7)bearing a rare oxepane ring,were isolated from sponge Acanthella cavernosa collected from the South China Sea.The structures and absolute ...
关键词:Acanthella cavernosa Kalihinenes Configuration determination CYTOTOXICITY Natural products 
Discovery of Kalmane Diterpenoids as Potent Analgesics from the Flowers of Rhododendron dauricum被引量:2
《Chinese Journal of Chemistry》2022年第9期1019-1027,共9页Yuanyuan Feng Suqin Zha Biao Gao Hanqi Zhang Pengfei Jin Guijuan Zheng Yilin Ma Guangmin Yao 
This work was financially supported by the Scientific Research Project of Traditional Chinese Medicine of Hubei Provincial Health Commission(ZY2021M056);the Open Project of State Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources(No.CMEMR-2021-B03)。
Kalmane diterpenoids,featuring a 5/8/5/5 tetracyclic carbon skeleton,are very rare in nature.The flowers of Rhododendron dauricum L.(Ericaceae)were phytochemically investigated for the first time,leading to the isolat...
关键词:Biological activity Kalmane diterpenoids Natural products Rhododendron dauricum L.(Ericaceae) Structure elucidation 
Distinctive Cassane Diterpenoids Corroborated Biogenetic Evolutionary Process from Caesalpinia mimosoides with Anti-renal Fibrosis Activity被引量:2
《Chinese Journal of Chemistry》2022年第5期617-627,共11页Xinxin Zhang Yan Yin Yu Zhou Tianliang Zhu Miao Wang Huiyuan Gao 
The authors are grateful to the received financial support from the National Natural Science Foundation of China(No.31670359);the Liaoning Revitallzation Talents Program(No.XLYC 1905019);the Natural Science Foundation of Llaoning Province(No.201602691).
Eighteen diterpenoids were isolated from the seeds of Caesalpinia mimosoides,including four extremely infrequent cassane diterpenes,together with nine new and five known structures.Compounds 7 and 8 represent the firs...
关键词:Cassane diterpene Caesalpinia mimosoides Natural products Molecular evolution Biological activity 
New Cembrane-Type Diterpenoids from the South China Sea Soft Coral Sinularia nanolobata
《Chinese Journal of Chemistry》2022年第1期28-38,共11页Na Lin Heng Li Jian-Rong Wang Wei Tang Ming-Yue Zheng Hong Wang Cheng-Shi Jiang Yue-Wei Guo 
financially supported by the National Key Research and Development Program of China(No.2018YFC0310903);the Natural Science Foundation of China(No.81991521);the SKLDR/SIMM Project(SIMM2103ZZ-06).
In the present study,nine new cembrane-type diterpenoids,namely ximaonanolobatins A—I(1—9),together with six related known analogs(10—15)and four known tetraprenylated alkaloids malonganenones D,E,H,and K(16—19)we...
关键词:Sinularia nanolobata Cembranoids X-ray diffraction Con figuration determination Natural products 
Discovery of Highly Oxidized Abietane Diterpenoids from the Roots of Euphorbia fischeriana with Anti-tumor Activities被引量:4
《Chinese Journal of Chemistry》2021年第11期2973-2982,共10页Jiang-Chun Wei Yu-Ning Gao Dong-Dong Wang Xiao-Yu Zhang San-Peng Fan Te-Ri-Gen Bao Xiao-Xu Gao Gao-Sheng Hu An-Hua Wang Jing-Ming Jia 
This work was supported by the National Key R&D Program of China(2017YFC1701200);the National Natural Science Foundation of China(81903789)。
Four previously undescribed ent-abietane diterpenoids(1—4),along with eleven known analogues(5—15),were isolated from the roots of wild Euphorbia fischeriana.Their gross structures were determined via extensive spec...
关键词:Euphorbia fischeriana DITERPENOIDS Structure elucidation Biological activity ANTI-TUMOR 
Isolation of Boswelliains A-E,Cembrane-Type Diterpenoids from Boswellia papyifera,and an Evaluation of Their Wound Healing Properties被引量:2
《Chinese Journal of Chemistry》2021年第9期2451-2459,共9页Qi-Hua Yu Madhu Babu Sura Dai-Wei Wang Danling Huang Yong-Ming Yan Ya-Bin Jiao Qing Lu Yong-Xian Cheng 
supported financially by the National Key Research and Development Program of China(No.2017YFA0503900);the National Science Fund for Distinguished Young Scholars(No.81525026);the Shenzhen Fundamental Research Program(No.JCYJ20200109114003921);the Guangdong Key Laboratory for Functional Substances in Medicinal Edible Resources and Healthcare Products(No.2021B1212040015);the SZU Top Ranking Project(No.86000000210);the National Natural Science Foundation of China(No.81903508).
Boswelliai ns A-E(1-5),five new cembra ne-type diterpenoids,were isolated from the resin of Boswellia papyifera.Their structures,determined by using spectroscopic,computational and chemical methods,demonstrate that 2-...
关键词:Boswellia papyifera Natural products Structure elucidation seco-Cembrane diterpenoids Wound healing 
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