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supported by the Seed Fund for Translational and Applied Research from the University Research Committee(URC),The University of Hong Kong(HKU),Hong Kong China(Project Codes:201910160024 and 202010160009).
Age-related osteoporosis is a metabolic skeletal disorder caused by estrogen deficiency in postmenopausal women.Prolonged use of anti-osteoporotic drugs such as bisphosphonates and FDA-approved anti-resorptive selecti...
Objective:To evaluate the antifertility activity of hydroalcoholic extract of Delonix regia(Boj.ex Hook.)Raf.leaves and seeds which are traditionally being used by Yanadi tribe to treat dysmenorrhea.Methods:Three expe...
It is unclear if complex mycotoxin mixtures produced by Alternaria spp.act estrogenic and/or genotoxic under physiological conditions,particularly considering the co-occurrence with antioxidants in food.Thus,this stud...
LAMP2(lysosome associated membrane glycoprotein 2)is an important autophagy protein but its role in estrogenic regulation on spatial learning and memory remains unclear.In this study,we first infused aromatase(estroge...
Objective:To assess the estrogenic activity of hydroalcoholic extract of Clitoria(C.)ternatea leaves in female Wistar rats.Methods:Hydroalcoholic extract of C.ternatea leaves prepared by using cold maceration method w...
support provided by the Natural Sciences and Engineering Research Council of Canada (NSERC) under the project Reducing Environmental Pollution from Veterinary Antibiotics, Endocrine Disruptive Chemicals, and Pathogens in Livestock Manure;the Department of Bioresource Engineering, McGill University for providing a Liliane and David Stewart Fellowship in Water Resources for support of this research work
Most animals, including humans, produce natural sex hormones such as estrogens: 17β-estradiol(E2) and estrone(E1). These compounds are able to disrupt the reproductive systems of living organisms at trace concentrati...
sponsored by the National Natural Science Foundation of China(No.41401558);the Application Fundamental Key Basic Research Foundation of Yunnan Province,China(No.2013FA011);the Education Department Science Research Foundation of Yunnan Province,China(No.2014J022);the China Postdoctoral Science Foundation(No.2014T70887)
17α-Ethynylestradiol(EE2) in natural waters may cause adverse effects on organisms due to its high estrogenic potency. Laboratory studies were performed to study the effects of a local humic acid(LHA), fulvic aci...
supported by grants from the Cancer Prevention Research Institute of Texas(RP130266);the Carson-Leslie Foundation and the Association for Research of Childhood Cancer
Endocrine therapy using estrogen receptor-u (ER-α) antagonists for attenuating horm2one-driven cell proliferation is a major treatment modality for breast cancers. To exploit any DNA repair deficiencies associated ...
support by National Natural Science Foundation of China (Nos. 41390240, 21477123);the Project for the Development of Ocean Economy in Fujian Province (No. 2014Y0046);the Key Laboratory of Urban Environment and Health, Chinese Academy of Sciences (IUEMS201405, KLUEH-S-201303)
Estrogenic pollution and its control in aquatic systems have drawn substantial attention around the world. The chemical and biological assessment approaches currently utilized in the laboratory or field cannot give an...
The evaluation of estrogenic activities and aryl hydrocarbon receptor (AhR) agonists in water from Three Gorges Reservoir (TGR) China was conducted by in vitro bioassays combined with SPMD-based virtual organisms (VO)...