BIOINFORMATIC

作品数：71被引量：91H指数：5
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TEGR:A comprehensive Ericaceae genome resource database
《Journal of Integrative Agriculture》2025年第3期1140-1151,共12页Xiaojing Wang Yunfeng Wei Zhuo Liu Tong Yu Yanhong Fu Xiaoming Song 
supported by the National Natural Science Foundation of China(32260097);the National Guidance of Local Science and Technology Development Fund of China([2023]009)。
Ericaceae is a diverse family of flowering plants distributed nearly worldwide,and it includes 126 genera and more than 4,000 species.In the present study,we developed The Ericaceae Genome Resource(TEGR,http://www.teg...
关键词：TEGR ERICACEAE gene functional annotation m^(6)A CRISPR bioinformatic tools 
Bioinformatics-based investigation of the therapeutic potential of Tongxinluo capsule in acute myocardial infarction
《Journal of Chinese Pharmaceutical Sciences》2024年第11期1040-1057,共18页Jingjing Su Kangkang Su Yanping Song Lihui Hao Xing Wang Linquan Yang Chao Wang Shuxia Chen Jian Gu 
Acute myocardial infarction(AMI)is associated with a challenging prognosis.Notably,the Tongxinluo capsule(TXL),a proprietary Chinese medicine,has garnered attention for its potential therapeutic effects.This study aim...
关键词：one BIOINFORMATICS Acute myocardial infarction Immune infiltration Proprietary Chinese medicine 
Hypoxia-related bioinformatic signatures associated with prognosis and tumor microenvironment of pancreatic cancer:Current status,concerns,and future perspectives
《World Journal of Gastroenterology》2024年第44期4689-4696,共8页Dong-Ming Li Xue-Yuan Cao Jing Jiang 
Supported by National Natural Science Foundation of China,No.82373664;Scientific and Technological Development Program of Jilin Province,No.20240402015GH.
Pancreatic cancer(PC),a highly lethal tumor with nearly identical incidence and mortality rates,has become the sixth leading cause of cancer-related deaths.Hypoxia is an important malignant factor in PC,as it regulate...
关键词：Pancreatic cancer HYPOXIA Bioinformatics analysis PROGNOSIS Tumor microenvironment 
Bioinformatic Resources for Exploring Human-virus Protein-protein Interactions Based on Binding Modes
《Genomics, Proteomics & Bioinformatics》2024年第5期45-59,共15页Huimin Chen Jiaxin Liu Gege Tang Gefei Hao Guangfu Yang 
supported by the National Natural Science Foundation of China(Grant No.32125033).
Historically,there have been many outbreaks of viral diseases that have continued to claim millions of lives.Research on human-virus protein-protein interactions(PPIs)is vital to understanding the principles of human-...
关键词：Artificial intelligence Bioinformatic resource Protein-protein docking Protein-protein interaction Viral pandemic 
Bioinformatic approaches of liquid-liquid phase separation in human disease
《Chinese Medical Journal》2024年第16期1912-1925,共14页Jun Sun Yilong Chen Ruiye Bi Yong Yuan Haopeng Yu 
funded by grants from the Natural Science Foundation of Guangdong Province,China(No.2023A1515010148);the Postdoctoral Fellowship Program of CPSF(No.GZC20241143);the China Postdoctoral Science Foundation(No.2024M752202);the National Natural Youth Science Foundation of China(No.32100927);the National Natural Science Foundation of China(No.81970481).
Biomolecular aggregation within cellular environments via liquid-liquid phase separation(LLPS)spontaneously forms droplet-like structures,which play pivotal roles in diverse biological processes.These structures are c...
关键词：Phase separation Liquid-liquid phase separation DISEASE Phase separation databases Bioinformatic tools 
The Bioinformatic Applications of Hi-C and Linked Reads
《Genomics, Proteomics & Bioinformatics》2024年第4期11-30,共20页Libo Jiang Michael A.Quail Jack Fraser-Govil Haipeng Wang Xuequn Shi Karen Oliver Esther Mellado Gomez Fengtang Yang Zemin Ning 
supported by from the National Natural Science Foundation of China(Grant No.32070601);the Natural Science Fund for Excellent Young Scholars of Shandong Province,China(Grant No.ZR2022YQ23);supported by the Wellcome Trust,UK(Grant No.WT206194).
Long-range sequencing grants insight into additional genetic information beyond what can be accessed by both short reads and modern longread technology.Several new sequencing technologies,such as“Hi-C”and“Linked Re...
关键词：Long-range NGS reads Hi-C Linked Reads Genome assembly Quality assessment. 
Toward the generation of pure coral genomes with experimental and bioinformatic improvements
《The Innovation》2024年第4期30-32,共3页Yisi Hu Zhiwei Zhang Shuyan Sun Youfang Sun Hui Huang Wenliang Zhou Fuwen Wei 
supported by Ministry of Science and Technology of the People’s Republic of China(2021YFF0502804);Science and Technology Department,Guangdong Province(2021QN02H103);Guangdong Forestry Administration(SLYJ2023B4004);China Postdoctoral Science Foundation(2023M740813);PI Project of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(GML2020GD0804,GML2022GD0804);Young Elite Scientists Sponsorship Program by CAST(2023QNRC001).
Stony corals,the primary architects of coral reef ecosystems,are largely underrepresented in omics studies despite their importance.The presence of endosymbiotic Symbiodiniaceae algae complicates the extraction of pur...
关键词：CORAL GUARANTEE PURITY 
Multivariate statistical and bioinformatic analyses for the seasonal variations of actinobacterial community structures in a drinking water reservoir
《Journal of Environmental Sciences》2024年第3期1-17,共17页Haihan Zhang Sixuan Pan BenMa Tinglin Huang Dmitry B.Kosolapov Manli Ma Xiang Liu Huan Liu Xiaoyan Liu 
supported by the National Natural Science Foundation of China (Nos.51978561,51979217,and 52270168);the National Key Research and Development Program of China (No.2022YFC3203604);the Youth Innovation Team of Shaanxi Universities (PI Zhang Haihan);the Grant from Youth Innovation Team of Shaanxi Universities in 2021 (No.21JP061);the Scientific Research Program Funded by Education Department of Shaanxi Provincial Government (No.22JY034);the Natural Science Basic Research Program of Shaanxi Province (No.2022JM-224)。
Actinobacterial community is a conspicuous part of aquatic ecosystems and displays an important role in the case of biogeochemical cycle,but little is known about the seasonal variation of actinobacterial community in...
关键词：Source water reservoir High-throughput sequencing Correlation analysis Network analysis Partial least squares path modeling 
Exploring the autophagy-related pathogenesis of active ulcerative colitis被引量：1
《World Journal of Clinical Cases》2024年第9期1622-1633,共12页Zhuo-Zhi Gong Teng Li He Yan Min-Hao Xu Yue Lian Yi-Xuan Yang Wei Wei Tao Liu 
BACKGROUND The pathogenesis of ulcerative colitis(UC)is complex,and recent therapeutic advances remain unable to fully alleviate the condition.AIM To inform the development of novel UC treatments,bioinformatics was us...
关键词：Ulcerative colitis AUTOPHAGY BIOINFORMATIC TARGETS PATHOGENESIS 
Adenylate cyclase activates the cAMP signalling pathway to enhance platelet-rich plasma-treated Achilles tendon disease,a theoretical bioinformatics-based study
《World Journal of Orthopedics》2024年第2期192-200,共9页Jing-Yi Sun Cai Li Feng-Ying Du 
The effectiveness of platelet-rich plasma(PRP)for the treatment of Achilles tendon disorders still needs to be evaluated through a series of prospective studies,but genomic analysis can reveal the existence of complem...
关键词：Platelet-rich plasma Achilles tendon disease CAMP Adenylate cyclase Complementary target 
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