云南高校图书馆联盟文献共享服务平台- ACARBOSE

ACARBOSE: 作品数：28被引量：117H指数：7; 导出分析报告; 相关作者：杨秀芳俞茂华孙侃朱禧星申竹芳更多>>; 相关机构：中国医学科学院北京协和医学院中国人民解放军总医院中山大学附属第三医院中山大学更多>>; 相关期刊：《Journal of Hainan Medical University》《China Medical Abstracts(Internal Medicine)》《Molecular Plant》《Synthetic and Systems Biotechnology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金更多>>

Acarbose glycosylation by AcbE for the production of acarstatins with enhancedα-amylase inhibitory activity: 《Synthetic and Systems Biotechnology》2024年第2期359-368,共10页Xin Zhang Qungang Huang Ziyue Guo Feifei Cai Qianjin Kang Linquan Bai; This work was supported by the National Key Research and Development Program of China(grant No.2021YFC2100600);National Natural Science Foundation of China(grant No.31830104);Science and Technology Commission of Shanghai Municipality(grant Nos.19JC1413000 and 19430750600)to L.B.We thank the Core Facility and Technical Service Center for SLSB and the Instrumental Analysis Center in SJTU for data collection.; Acarbose is a potent glycosidase inhibitor widely used in the clinical treatment of type 2 diabetes mellitus(T2DM).Various acarbose analogs have been identified while exploring compounds with improved pharmacological ...; 关键词：Acarbose analogs α-amylase inhibitory activity Actinoplanes sp. Transglycosylase

Mediating effect of acarbose on neurotransmitters in mental disorders: a review: 《Journal of Translational Neuroscience》2023年第3期14-19,共6页Huasu Liang; Acarbose is used to control postpran-dial blood glucose in patients with type 2 diabetes and impaired glucose tolerance,since it improves insulin resistance and reduces blood lipids and cardiovascular complications.Ho...; 关键词：ACARBOSE NEUROTRANSMITTER INSULIN brain-gut axis calorie restriction

New polychlorinated bibenzyls from Rhododendron minutiflorum: 《Natural Products and Bioprospecting》2023年第1期709-717,共9页Yang-Li Zhu Li Deng Yu Tang Xian-Zhe Fan Yang Han Mei Pan Li-Jun Zhang Hai-Bing Liao; The Natural Science Foundation of China(32160109,31800294);the Natural Science Foundation of Guangxi Province of China(2018GXNSFBA138006,2019AC20231);Educational Department of Guangxi(2018KY0089);the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources(CMEMR2017-A07,2020-A09);Joint cultivation base of biology and medicine graduate student between Guangxi Normal University and Guilin Pharma Company.; Five new polychlorinated bibenzyls(1-5)along with 3 known compounds(6-8)were isolated from the stems and leaves of Rhododendron minutiflorum.The chemical structures of all the isolates were determined by spectroscopic...; 关键词：Rhododendron minutiflorum Polychlorinated bibenzyls MATRINE Insecticidal activity Diaphorina citri α-Glucosidase inhibitory activity ACARBOSE

Acarbose is again on the stage被引量：1: 《World Journal of Diabetes》2022年第1期1-4,共4页Mustafa Altay; Acarbose is an agent that has been used to treat type 2 diabetes for about 30 years;it prevents postprandial hyperglycemia by inhibiting carbohydrate digestion in the small intestine.Since incretin-based treatments ha...; 关键词：ACARBOSE Cardiovascular protection Glucagon-like peptide 1 OBESITY Waist-to-height ratio

Diabetes patients with comorbidities had unfavorable outcomes following COVID-19:A retrospective study: 《World Journal of Diabetes》2021年第10期1789-1808,共20页Shun-Kui Luo Wei-Hua Hu Zhan-Jin Lu Chang Li Ya-Meng Fan Qi-Jian Chen Zai-Shu Chen Jian-Fang Ye Shi-Yan Chen Jun-Lu Tong Ling-Ling Wang Jin Mei Hong-Yun Lu; Supported by National Natural Science Foundation of China(General Program);No.81670815;Guangdong Basic and Applied Basic Research Foundation,No.2020A1515010124,No.2021A1515010695;Special Fund for Innovation Strategy of Science and Technology plan of Guangdong Province,No.2019A030317011。; BACKGROUND Previous studies have shown that diabetes mellitus is a common comorbidity of coronavirus disease 2019(COVID-19),but the effects of diabetes or anti-diabetic medication on the mortality of COVID-19 have not...; 关键词：DIABETES Coronavirus disease 2019 MORTALITY Risk factors ACARBOSE

Factors associated with improvement in waist-to-height ratio among newly diagnosed type 2 diabetes patients treated with acarbose or metformin:A randomized clinical trial study被引量：1: 《World Journal of Diabetes》2020年第11期514-526,共13页Lu-Lu Song Xin Wang Zhao-Jun Yang Xiao-Mu Kong Xiao-Ping Chen Bo Zhang Wen-Ying Yang; This study is registered at Chinese Clinical Trial Registry Center.The registration number is ChiCTRTRC-08000231.; BACKGROUND The waist-to-height ratio(WHtR)is a promising anthropometric measure used to evaluate cardiovascular risk in diabetes and metabolic syndrome patients.The metformin and acarbose in Chinese as the initial hyp...; 关键词：Waist-to-height ratio Abdominal obesity Type 2 diabetes ASSOCIATION ACARBOSE METFORMIN

Comparative functional genomics of the acarbose producers reveals potential targets for metabolic engineering被引量：7: 《Synthetic and Systems Biotechnology》2019年第1期49-56,共8页Huixin Xie Qinqin Zhao Xin Zhang Qianjin Kang Linquan Bai; the National Natural Science Foundation of China(No.31470157,21661140002,31830104,U1703236);the Shanghai Science and Technology Committee(No.17JC1403600)。; Theα-glucosidase inhibitor acarbose is produced in large-scale by strains derived from Actinoplanes sp.SE50 and used widely for the treatment of type-2 diabetes.Compared with the wild-type SE50,a high-yield derivativ...; 关键词：ACARBOSE Comparative genomics OVERPRODUCTION Regulation

Comparison of acarbose and metformin as add-on therapy to insulin in uncontrolled patients with type 2 diabetes mellitus: A randomized,openlabeled,and parallel group study被引量：1: 《China Medical Abstracts(Internal Medicine)》2018年第4期210-211,共2页ZHANG Qiongge; Objective To evaluate efficacy and safety of acarbose compared with metformin as add-on therapy in patients with type 2 diabetes mellitus inadequately controlled with insulin.Methods This was a randomized,open-labeled...; 关键词：METFORMIN INSULIN effect was INS Aca Met vs

Improving acarbose production and eliminating the by-product component C with an efficient genetic manipulation system of Actinoplanes sp.SE50/110被引量：9: 《Synthetic and Systems Biotechnology》2017年第4期302-309,共8页Qinqin Zhao Huixin Xie Yao Peng Xinran Wang Linquan Bai; We are grateful to Prof.Yuhui Sun from Wuhan university,China,and the late Prof.Keqian Yang from Institute of Microbiology,Chinese Academy of Sciences,for providing plasmids pWHU2653 and pDR-4-K^*,respectively.This work was supported by grants from the National Natural Science Foundation of China(No.31470157,21661140002);the Ministry of Science and Technology of China(No.2012AA02A706).; Theα-glucosidase inhibitor acarbose is commercially produced by Actinoplanes sp.and used as a potent drug in the treatment of type-2 diabetes.In order to improve the yield of acarbose,an efficient genetic manipulatio...; 关键词：Actinoplanes sp. ACARBOSE Genetic manipulation CONJUGATION Component C

The ACE trial： a new perspective on the effect of acarbose on cardiovascular outcomes: 《中华内分泌代谢杂志》2017年第12期1012-1014,共3页Chantal Mathieu; 关键词：《中华内分泌代谢杂志》期刊编辑工作发行工作

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