POLYMORPHONUCLEAR

作品数：24被引量：117H指数：6
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相关作者：沈放程桂芳李良成阚全程赵院霞更多>>
相关机构：中国医学科学院中国协和医科大学中国医学科学院基础医学研究所郑州大学第一附属医院更多>>
相关期刊：《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《中国实用医刊》更多>>
相关基金：国家自然科学基金河北省自然科学基金广东省自然科学基金更多>>
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Aryl hydrocarbon receptor activation drives polymorphonuclear myeloid-derived suppressor cell response and efficiently attenuates experimental Sjögren’s syndrome被引量：4
《Cellular & Molecular Immunology》2022年第12期1361-1372,共12页Yanxia Wei Na Peng Chong Deng Futao Zhao Jie Tian Yuan Tang Sulan Yu Yacun Chen Yu Xue Fan Xiao Yingbo Zhou Xiaomei Li Hejian Zou Ke Rui Xiang Lin Liwei Lu 
supported by the Chongqing International Institute for Immunology (2020YJC10);the National Natural Science Foundation of China (NSFC) (82071817,81971542,and 82171771);the Hong Kong Research Grants Council General Research Fund (17113319 and 27111820);Theme-Based Research Scheme (T12-703/19 R);the Shenzhen Science and Technology Program (YCYJ20210324114602008);the Centre for Oncology and Immunology under the Health@InnoHK Initiative of the Innovation and Technology Commission,Hong Kong,China.
Myeloid-derived suppressor cells(MDSCs)comprise heterogeneous myeloid cell populations with immunosuppressive capacity that contribute to immune regulation and tolerance induction.We previously reported impaired MDSC ...
关键词：myeloid-derived suppressor cell Sjogren's syndrome Aryl hydrocarbon receptor 
Continuous activation of polymorphonuclear myeloid-derived suppressor cells during pregnancy is critical for fetal development被引量：3
《Cellular & Molecular Immunology》2021年第7期1692-1707,共16页Mengyu Shi Ziyang Chen Meiqi Chen Jingping Liu Jing Li Zhe Xing Xiaogang Zhang Shuaijun Lv Xinyao Li Shaowen Zuo Shi Feng Ying Lin Gang Xiao Liping Wang Yumei He 
supported by grants from the following institutions:the High-level Talent Start-up Funding of Southern Medical University;the National Natural Science Foundation of China(grant numbers:31700061,81971420 and 81991511);the Guangdong Special Support Program for Youth Science and Technology Innovation Talents(grant number:2019TQ05Y585);the National Natural Science Foundation of Guangdong(grant number:2019A1515011435);the Science and Technology Program of Guangzhou(grant number:201904010073).
The maternal immune system is vital in maintaining immunotolerance to the semiallogeneic fetus for a successful pregnancy.Although studies have shown that myeloid-derived suppressor cells(MDSCs)play an important role ...
关键词：Polymorphonuclear myeloid-derived suppressor cells Class E scavenger receptor 1 IMMUNOTOLERANCE 
Targeting and exploitation of tumor-associated neutrophils to enhance immunotherapy and drug delivery for cancer treatment被引量：16
《Cancer Biology & Medicine》2020年第1期32-43,共12页Yuting Zhang Guoqiang Liu Miaomiao Sun Xin Lu 
partly supported by a graduate fellowship from China Scholarship Council(Grant No.201708340071);partly supported by a Career Catalyst Research Grant(Grant No.18548293)from the Susan G.Komen Foundation;a Cancer Research Grant from the Mary Kay Foundation;a Research Grant from the Elsa U.Pardee Foundation。
Neutrophils,the most abundant leukocytes in human blood,are essential fighter immune cells against microbial infection.Based on the finding that neutrophils can either restrict or promote cancer progression,tumor-asso...
关键词：Tumor-associated neutrophil polymorphonuclear myeloid-derived suppressor cell IMMUNOSUPPRESSION cancer immunotherapy nanoparticle drug delivery 
Serum Resistin Level and Polymorphonuclear Leukocytes Dysfunctions in Children on Regular Hemodialysis被引量：1
《International Journal of Clinical Medicine》2015年第6期423-430,共8页Maha Yousef Zein Manal Abdel-Salam Iman Abdel-Aziz Naglaa Fathy Mohamed 
Resistin is a secretory adipocytoine, which is expressed mainly in humans by inflammatory cells especially macrophages. Resistin serum levels are elevated in end-stage renal diseases of people having an increased risk...
关键词：Chronic KIDNEY Disease RESISTIN DIALYSIS POLYMORPHONUCLEAR Leukocytes 
Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome被引量：4
《World Journal of Gastroenterology》2014年第2期363-375,共13页Jan Dabritz Jason Musci Dirk Foell 
A research fellowship awarded to Dabritz J by the German Research Foundation;No.DFG DA1161/5-1
Irritable bowel syndrome(IBS)is a common functional gastrointestinal(GI)disorder characterized by unspecific symptoms.In clinical practice it is crucial to distinguish between non-inflammatory functional problems and ...
关键词：S100A12 CALPROTECTIN LACTOFERRIN M2-pyruvate kinase Polymorphonuclear elastase DEFENSINS Granins Irritable bowel syndrome 
Measurement of calprotectin in ascitic fluid to identify elevated polymorphonuclear cell count被引量：10
《World Journal of Gastroenterology》2013年第13期2028-2036,共9页Emanuel Burri Felix Schulte Jürgen Muser Rémy Meier Christoph Beglinger 
Supported by Unrestricted Research Grants (to Burri E) by the Freiwillige Akademische Gesellschaft (Basel, Switzerland) and the Gottfried und Julia Bangerter-Rhyner-Stiftung (Bern,Switzerland);Bühlmann Laboratories AG (Sch nenbuch, Switzerlanfd) provided the assays to measure ascitic calprotectin
AIM: To evaluate the diagnostic capability of calprotectin in ascitic fluid for detecting a polymorphonuclear (PMN) cell count > 250/μL ascites. METHODS: In this prospective observational study, a total of 130 ascite...
关键词：CALPROTECTIN ASCITES Liver CIRRHOSIS Spontaneous bacterial PERITONITIS POLYMORPHONUCLEAR cells 
Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis被引量：13
《World Journal of Gastroenterology》2013年第8期1271-1277,共7页Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf Mohamed Hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly 
AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial peritonitis.METHODS:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid pol...
关键词：Spontaneous bacterial PERITONITIS CEFOTAXIME ASCITIC POLYMORPHONUCLEAR count Cirrhosis MEROPENEM LEVOFLOXACIN 
Sulfur dioxide attenuates LPS-induced acute lung injury via enhancing polymorphonuclear neutrophil apoptosis被引量：6
《Acta Pharmacologica Sinica》2012年第8期983-990,共8页Hui-jie MA Xin-li HUANG Yan LIU Ya-min FAN 
This research program was supported by the National Natu-ral Science Foundation of China （No 81070050 and 30800440） and the Natural Science Foundation of Hebei Province （No C2007000830, C2008001040, and H2012206009）.
Aim： We speculated that the enhanced apoptosis of polymorphonuclear neutrophil （PMN） might be responsible for the inhibition of PMN infiltration in the lung. This study was designed to investigate the effects of su...
关键词：acute lung injury bronchoalveolar lavage fluid （BALF） LIPOPOLYSACCHARIDE SO2 apoptosis polymorphonuclear granulocyte 
Efficacy of boswellic acid on lysosomal acid hydrolases,lipid peroxidation and anti-oxidant status in gouty arthritic mice被引量：6
《Asian Pacific Journal of Tropical Biomedicine》2012年第2期128-133,共6页Evan Prince Sabina Haridas Indu Mahaboobkhan Rasool 
Objective:To evaluate the efficacy of boswellic acid against monosodium urate crystal-induced inflammation in mice.Methods:The mice were divided into four experimental groups.GroupⅠserved as control;mice in groupⅡwe...
关键词：Boswellic ACID GOUTY arthritis Indomethacin LYSOSOMAL enzymes POLYMORPHONUCLEAR LEUCOCYTES Monosodium urate Lipid peroxidation Antioxidant STATUS Anti-inflammatory effect Antiarthritic effect Inflammation 
TAT-BPI融合蛋白原核表达载体的构建
《中国实用医刊》2010年第9期33-35,共3页赵院霞 阚全程 余祖江 
目的 探讨使BPI能高效率穿透细胞膜或多种屏障,中和不同解剖部位的LPS,构建TAT-BPI原核表达载体并鉴定的方法,为研制多肽抗生素打下基础.方法 人工合成编码TAT蛋白转导区的DNA片段,插入载体pUC57后得到pUC57-TAT重组质粒;提取正常人外...
关键词：融合蛋白 原核表达载体 表达载体的构建 expression vector BPI Restriction enzyme 氨基酸同源性 TAT protein POLYMORPHONUCLEAR neutrophils DNA sequence analysis 基因片段序列 human cell membrane 双脱氧测序法 核苷酸 多形核粒细胞 蛋白质 DNA fragment 同源性分析 多肽抗生素 
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