FIBROGENESIS

作品数：46被引量：605H指数：15
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相关领域：医药卫生更多>>
相关作者：陈志南边惠洁李浩吴佼更多>>
相关机构：第四军医大学同济大学上海中医药大学更多>>
相关期刊：《Journal of Bio-X Research》《World Journal of Gastroenterology》《肝脏》《Current Medical Science》更多>>
相关基金：国家自然科学基金河北省自然科学基金上海市教育委员会重点学科基金广西壮族自治区自然科学基金更多>>
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Integrative omics analysis identifies macrophage migration inhibitory factor signaling pathways underlying human hepatic fibrogenesis and fibrosis被引量：1
《Journal of Bio-X Research》2019年第1期16-24,共9页Zhipeng Liu Naga Chalasani Jingmei Lin Samer Gawrieh Yuan He Yan J.Tseng Wanqing Liu 
supported in part by a NIH grant,No.R01 DK106540(to WL).
The genetic basis underlying liver fibrosis remains largely unknown.We conducted a study to identify genetic alleles and underlying pathways associated with hepatic fibrogenesis and fibrosis at the genome-wide level i...
关键词：hepatic fibrosis GENOMICS macrophage migration inhibitory factor alpha-smooth muscle actin pathway enrichment analysis genetic susceptibility 
How tubular epithelial cells dictate the rate of renal fibrogenesis?被引量：17
《World Journal of Nephrology》2015年第3期367-373,共7页Kevin Louis Alexandre Hertig 
The main threat to a kidney injury, whatever its cause and regardless of whether it is acute or chronic, is the initiation of a process of renal fibrogenesis, since fbrosis can auto-perpetuate and is of high prognosti...
关键词：EPITHELIUM FIBROBLASTS Acute kidney injury Chronic kidney diseases FIBROSIS 
Fibrogenesis in alcoholic liver disease被引量：4
《World Journal of Gastroenterology》2014年第25期8048-8054,共7页Hideki Fujii Norifumi Kawada 
Supported by A grant-in-Aid for Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS) through grant No.25293177 to Kawada N (2013-2016);a Grant-in-Aid for Scientific Research (C) from the JSPS through grant No.25461007 to Fujii H(2013-2016)
Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. In developed countries, ALD is a major cause of end-stage liver disease that requires transplantation. The spectrum of ALD includes ...
关键词：Stellate cell Kupffer cell STEATOHEPATITIS FIBROSIS CYTOKINE Oxidative stress 
Fibrogenesis and fibrosis in inflammatory bowel diseases:Good and bad side of same coin?被引量：2
《World Journal of Gastrointestinal Pathophysiology》2013年第4期100-107,共8页Mariabeatrice Principi Floriana Giorgio Giuseppe Losurdo Viviana Neve Antonella Contaldo Alfredo Di Leo Enzo Ierardi 
Fibrogenesis in inflammatory bowel diseases is a complex phenomenon aimed at mucosal repair. However, it may provoke intestinal fibrosis with the development of strictures which require surgery. Therefore, fibrogenes...
关键词：FIBROGENESIS FIBROSIS Tumor necrosis factor-α SYNDECAN 1 Basic FIBROBLAST growth FACTOR Cellular fibrogenic phenotype Inflammatory bowel diseases 
Schistosoma japonicum egg antigen up-regulates fibrogenesis and inhibits proliferation in primary hepatic stellate cells in a concentration-dependent manner被引量：8
《World Journal of Gastroenterology》2013年第8期1230-1238,共9页Ping Liu Mi Wang Xiao-Dan Lu Shu-Juan Zhang Wang-Xian Tang 
Supported by Natural Science Foundation of China,No. 81071381
AIM:To investigate the effects of different concentrations of Schistosoma japonicum(S.japonicum) egg antigen on fibrogenesis and apoptosis in primary hepatic stellate cells(HSCs).METHODS:A mouse model of schistosomias...
关键词：SCHISTOSOMIASIS Liver FIBROSIS Hepatic stellate cells MITOGEN-ACTIVATED protein KINASE Akt 
Paediatric cholestatic liver disease:Diagnosis,assessment of disease progression and mechanisms of fibrogenesis被引量：7
《World Journal of Gastrointestinal Pathophysiology》2010年第2期69-84,共16页Tamara N Pereira Meagan J Walsh Peter J Lewindon Grant A Ramm 
Supported by a Project Grant from the National Health and Medical Research Council of Australia(NHMRC#496602 to GAR and PJL);Dr.Tamara Pereira is Supported by the Phillip Bushell Foundation Post-Doctoral Research Fellowship from the Gastroenterological Society of Australia;Associate Professor Grant A Ramm is Supported by a NHMRC Senior Research Fellowship(NHMRC#552409)
Cholestatic liver disease causes significant morbidity and mortality in children.The diagnosis and management of these diseases can be complicated by an inability to detect early stages of fibrosis and a lack of adequ...
关键词：CYSTIC FIBROSIS Biliary ATRESIA Liver biopsy Ultrasound HEPATIC FIBROSIS Cirrhosis HEPATIC stellatecell Bile acid CHEMOTAXIS Monocyte CHEMOTAXIS protein-1 
T cell immune response is correlated with fibrosis and inflammatory activity in hepatitis B cirrhotics被引量：14
《World Journal of Gastroenterology》2006年第19期3015-3019,共5页Jie-Ting Tang Jing-Yuan Fang Wei-Qi Gu En-Lin Li 
Supported by Shanghai Leading Academic Discipline Project,No. Y0205
AIM： TO explore the relationship among interferon-γ （IFN-γ） activity, fibrogenesis, T cell immune responses and hepatic inflammatory activity. METHODS： Peripheral blood samples from a total of 43 hepatitis B cir...
关键词：T cell immune responses Interferon-γ activity FIBROGENESIS Hepatic inflammatory activity 
Smad3 knock-out mice as a useful model to study intestinal fibrogenesis被引量：3
《World Journal of Gastroenterology》2006年第8期1211-1218,共8页Giuliana Zanninelli Antonella Vetuschi Roberta Sferra Angela D'Angelo Amato Fratticci Maria Adelaide Continenza Maria Chiaramonte Eugenio Gaudio Renzo Caprilli Giovanni Latella 
AIM： To evaluate the possible differences in morphology and immunohistochemical expression of CD3, transforming growth factor 131（TGF-131）, Smad7, α-smooth muscle actin （α-Sma）, and collagen types Ⅰ-Ⅶ of smal...
关键词：Transforming growth factor TGF-13 FIBROSIS Smad proteins 
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