ISOINDOLINONES

作品数:8被引量:0H指数:0
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相关领域:理学更多>>
相关期刊:《有机化学》《Organic Chemistry Frontiers》《Science China Chemistry》《Chinese Journal of Catalysis》更多>>
相关基金:国家自然科学基金更多>>
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Rh(Ⅲ)-Catalyzed Aminoalkylation of Alkenes with Diazo Compounds toward Functionalized Isoindolinones
《有机化学》2024年第11期3505-3517,共13页Yuying Liu Zhanwei Fu Chao Yang Mupeng Luo Shurong Ban Shouguo Wang 
山西省自然科学基金(No.202303021221131);山西省特色药物研制工程研究中心和深圳市科技创新委员会(Nos.JCYJ20210324101810028,JCYJ-20220818101601004,JCYJ20220818095801004)资助项目.
A[Cp*RhCl_(2)]_(2)-catalyzed intramolecular annulation reaction via aminoalkylation of alkenes with diazo compounds has been developed to construct highly-functionalized isoindolinones.This approach exhibits step econ...
关键词:aminoalkylation reaction annulation reaction ISOINDOLINONE Rh(Ⅲ)-catalysis diazo compounds 
Isocyanide-Based One-Pot Cascade Synthesis of 3-Acyl Isoindolinones
《Chinese Journal of Chemistry》2024年第3期259-263,共5页Jia Liu Yi-Ming Zhu Xiao-Ping Xu Shun-Jun Ji 
the National Natural Science Foundation of China(Nos.21772138 and 21672157);the Natural Science Foundation of Jiangsu Province(BK20221356);PAPD。
A series of 3-acyl-substituted isoindolinone derivatives were synthesized in a one-pot manner via the reaction of o-bromobenzaldehydes,isocyanides,and carboxylic acids in the presence of palladium catalyst and base. T...
关键词:One-pot reaction ISOCYANIDE Pd catalysis Rearrangement reaction ISOINDOLINONE 
Cobalt-Catalyzed Switchable[4+1]and[4+1+1]Spirocyclization of Aromatic Amides with 2-Diazo-1H-indene-1,3(2H)-dione:Access to Spiro Indene-2,1'-isoindolinones and Spiro Isochroman-3,1'-isoindolinones
《Chinese Journal of Chemistry》2024年第4期363-369,共7页Bin Li Mengmeng Xie Jingyu Li Nana Shen Xinying Zhang Xuesen Fan 
the National Natural Science Foundation of China(22101075,U2004189);Central Plains Science and Technology Innovation Leader Project(224200510009);Postdoctoral Research Grant in Henan Province(202103085);Henan Key Laboratory of Organic Functional Molecules and Drug Innovation,and 111 Project(D17007)for financial support.
Herein,we report a condition-controlled divergent synthesis of spiro indene-2,1'-isoindolinones and spiro isochroman-3,1'-isoindolinones through cobalt-catalyzed formal[4+1]and[4+1+1]spirocyclization of aromatic amide...
关键词:Spiro indene-2 1'-isoindolinones Spiro isochroman-3 1'-isoindolinones 3d Transition metals Cobalt-catalyzed C-H Activation Switchable[4+1]and[4+1+1]spirocyclization Aromatic amides 2-Diazo-1H-indene-1 3(2H)-dione 
A H_(4)SiW_(12)O_(40)-catalyzed three-component tandem reaction for the synthesis of 3,3-disubstituted isoindolinones
《Chinese Chemical Letters》2024年第1期233-236,共4页Yufeng Liu Guodong Zeng Yutao Cheng Lei Chen Yunhai Liu Yongge Wei Guoping Yang 
the National Natural Science Foundation of China(No.22001034);Jiangxi Provincial Natural Science Foundation(No.20212BAB213001).
A H_(4)SiW_(12)O_(40)-catalyzed three-component tandem reaction of 2-acylbenzoic acids,primary amines and phosphine oxides to form 3,3-disubstituted isoindolinones was developed.By employing A H_(4)SiW_(12)O_(40)as th...
关键词:POLYOXOMETALATES Dehydrative coupling Three-component tandem reaction 3 3-Disubstituted isoindolinones Organic carbonate 
Enantioselective construction of a congested quaternary stereogenic center in isoindolinones bearing three aryl groups via an organocatalytic formal Betti reaction
《Organic Chemistry Frontiers》2022年第2期428-435,共8页Arben Berisa Danijel Glavac Chao Zheng Shu-Li You Matija Gredicak 
provided by the Croatian Science Foundation(grant no.IP-2018-01-4053);Science and Technology Commission of Shanghai Municipality(grant no.19590750400).
An efficient enantioselective formal Betti reaction between phenols and diaryl ketimines generated in situ from isoindolinone alcohols is described.In a reaction catalyzed by a chiral phosphoric acid,a broad range of ...
关键词:QUATERNARY FORMAL STEREO 
Metal-Free Catalyzed Cyclization of N-Methoxybenzamides to Construct Quaternary Carbon-Containing Isoindolinones
《Chinese Journal of Chemistry》2021年第4期903-908,共6页Lin-Bao Zhang Zi-Chen Wang Sheng-Zheng Sun Shao-Fei Ni Li-Rong Wen Ming Li 
the National Natural Science Foundation of China(Nos.21801152 and 21572110);the Natural Science Foundation of Shandong Province(Nos.ZR2019BB005 and ZR2019MB010)for financial support;Shao-Fei Ni acknowledge funding from the STU Scientific Research Foundation for Talents(NTF20022).
Main observation and conclusion Through the intramolecular cyclization of N-methoxybenzamides,a simple and efficient method for constructing valuable isoindolinones under metal-free conditions was developed.The reacti...
关键词:Quaternary carbe Density functional theory ANNULATION ALKYNES Synthetic methods 
Trifluoromethyl radical triggered radical cyclization of N-benzoyl ynamides leading to isoindolinones
《Science China Chemistry》2019年第11期1542-1546,共5页Maud Cassé Christian Nisole Héloise Dossmann Yves Gimbert Jean-Marie Fourquez Laure Haberkorn Cyril Ollivier Louis Fensterbank 
Sorbonne Université;CNRS;Servier for funding
Under photocatalytic reductive conditions,trifluoromethyl radical addition onto an ynamide followed by cyclization on a benzoyl moiety produces diverse isoindolinone platforms with good yields.The selectivity of the r...
关键词:YNAMIDES TRIFLUOROMETHYLATION photocatalysis cascade reactions tandem processes ISOINDOLINONES modeling 
Rhodium(Ⅲ)-catalyzed selective access to isoindolinones via formal [4+1] annulation of arylamides and propargyl alcohols
《Chinese Journal of Catalysis》2017年第8期1390-1398,共9页Youwei Xu Fen Wang Songjie Yu Xingwei Li 
supported by the Dalian Institute of Chemical Physics,Chinese Academy of Sciences;the National Natural Science Foundation of China (21525208,21472186)~~
A mild and efficient oxidative synthesis of isoindolinones has been realized by Rh(III)‐catalyzed C?H activation of benzamides and[4+1]coupling with propargyl alcohols.This coupling system proceeds with broad substra...
关键词:RHODIUM C-H activation [4+1] annulation Propargyl alcohol ISOINDOLINONES 
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