云南高校图书馆联盟文献共享服务平台- ENT-KAURANE

ENT-KAURANE: 作品数：35被引量：36H指数：3; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：李志成更多>>; 相关机构：北京大学兰州大学中国科学院更多>>; 相关期刊：《Chinese Journal of Structural Chemistry》《Journal of Chinese Pharmaceutical Sciences》《Natural Products and Bioprospecting》《Chinese Herbal Medicines》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金河北省自然科学基金更多>>

Ent-pimarane and ent-kaurane diterpenoids from Siegesbeckia pubescens and their anti-endothelial damage effect in diabetic retinopathy: 《Chinese Journal of Natural Medicines》2025年第2期234-244,共11页Mengjia Liu Tingting Luo Rongxian Li Wenying Yin Fengying Yang Di Ge Na Liu; supported by the National Natural Science Foundation of China (No.82073728);the Natural Science Foundation of Shandong Province (No.ZR2021MH357)。; Diabetic retinopathy,a prevalent and vision-threatening microvascular complication of diabetes mellitus,is the leading cause of blindness among middle-aged and elderly individuals.Natural diterpenoids isolated from Si...; 关键词：Siegesbeckia pubescens Natural diterpenoid Diabetic retinopathy Oxidative stress Inflammatory response

Network pharmacology-based strategy to investigate harmacological mechanisms of Isodon serra(Maxim.)Hara for treatment of inflammatory被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2022年第4期250-263,共14页Weiwei Xie Xuqing Wen Dedong Zhang Yuqian Zhang Zhiqing Zhang Yiran Jin Yingfeng Du; Hebei Administration of Traditional Chinese Medicine(Grant No.2021133);the Natural Science Foundation of Hebei Province of China(Grant No.H2019206562);the Key Projects of Hebei Education Department(Grant No.ZD2017244)。; Widely distributed in plants,ent-kaurane diterpenoids could reduce the incidence of inflammatory.The most important active ingredient of Isodon serra(Maxim.)Hara is ent-kaurane diterpenoids,which contribute to the ant...; 关键词：Isodon serra(Maxim.)Hara Network pharmacology Active compounds ent-Kaurane diterpenoids Inflammatory targets

New ent-kaurane diterpenes with chiral epoxyangelate moieties from Wedelia prostrata: 《Chinese Chemical Letters》2019年第2期451-453,共3页Zhongnan Wu Yubo Zhang Wen Li Nenghua Chen Qianwen Niu Yingying Li Qingguo Li Dan Yang Yaolan Li Guocai Wang; financially supported by the National Natural Science Foundation of China(Nos.81473116,81673319,81673670);Science and Technology Planning Project of Guangdong Province (Nos. 2016A030303011, 2016B030301004);Natural Science Foundation of Guangdong Province(No. 2017A030313732);China Postdoctoral Science Foundation(No. 55350202);Natural Science Foundation of Chongqing(No. cstc2013jcyjA10065); Four new ent-kaurane diterpenes with chiral epoxyangelate moieties, (2′R,3′R)-3 a- (2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (1), (2′S,3′S)-3 a- (2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (2), (2′...; 关键词：Wedelia prostrata CHIRAL epoxyangelate MOIETIES ENT-KAURANE DITERPENES ABSOLUTE configuration CYTOTOXICITY activities

Scopariusols L–T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius被引量：1: 《Chinese Journal of Natural Medicines》2018年第6期456-464,共9页JIANG Hua-Yi LI Xiao-Nian SUN Han-Dong ZHANG Hong-Bin PUNO Pema-Tenzin; supported by the National Natural Science Foundation of China(No.21322204);the NSFC-Joint Foundation of Yunnan Province(No.U1302223); Nine new ent-kaurane diterpenoids, named scopariusols L–T(1–9), were isolated from the aerial parts of Isodon scoparius. Their structures were characterized mainly by analyzing the NMR and HR-ESI-MS data, and the ab...; 关键词：ISODON scoparius ENT-KAURANE DITERPENOIDS X-ray diffraction CYTOTOXICITY ANTI-INFLAMMATORY activity

Antitumor activityand mechanism of JD20,a newly synthetic analog of natural ent-kaurane diterpenoid: 《中国药理学与毒理学杂志》2018年第4期346-346,共1页Ying-li ZHU Xia-xia FAN Ya-fei LI Ao JIA Bei-bei SHAO Ai-feng WANG Yong-cheng MA; supported by National Natural Science Foundation of China(81502952); OBJECTIVE To study the anti-tumor activity and molecular mechanism of natural diter.pene derivative JD20 in vitro.METHODS Screening the sensitive of gastric carcinoma cell lines to JD20 by cytotoxicity test for 24 h.C...; 关键词：细胞色素线粒体治疗方法临床分析

Fimbrialtols K–M, highly functionalized ent-kaurane diterpenoids from traditional Chinese plant Flickingeria fimbriata(B1.) Hawkes: 《Chinese Chemical Letters》2017年第3期593-596,共4页Gang Ding Jing Wang Jiao-Dong Fei Rong-Tao Li Hong-Mei Jia Tao Zhang Chang-Yuan Yu Zhong-Mei Zou 无; financially supported by the Chinese National S&T Special Project on Major New Drug Innovation(No.2013ZX09508104);the Fundamental Research Funds for the Central Scientific Research Institutes for Public Welfare;CAMS Innovation Fund for Medical Sciences(CIFMS,No.2016-I2M-3-015); Three new ent-kaurane diterpenoids fimbrialtols K–M（3–5） with highly substituted functionalities were isolated from the extract of Flickingeria fimbriata（B1.） Hawkes. The structures of these new compounds were d...; 关键词：Flickingeria fimbriata（B1.） Hawkes ent-Kaurane diterpenoids Fimbrialtols NMR CD

Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys被引量：2: 《Science China Chemistry》2016年第9期1211-1215,共5页Jin Yang Yaqi An Haiyan Wu Miao Liu Weiguang Wang Xue Du Yan Li Jianxin Pu Handong Sun; supported by the NSFC-Joint Foundation of Yunnan Province (U1302223);the National Natural Science Foundation of China (21322204);the West Light Foundation of the Chinese Academy of Sciences (J-X Pu); Four new diterpenoids, phyllostachysins I-L （1-4）, along with a known one, hebeiabinin B （5）, were isolated from the aerial parts oflsodonphyllostachys （I.phyllostachys）. Compounds 1 and 2 feature an ent-kaurane...; 关键词：lsodon phyllostachys DITERPENOID ENT-KAURANE ent-abietane

Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans被引量：3: 《Natural Products and Bioprospecting》2016年第4期217-223,共7页Rui Chu Luo-Sheng Wan Xing-Rong Peng Mu-Yuan Yu Zhi-Run Zhang Lin Zhou Zhong-Rong Li Ming-Hua Qiu; This work was supported financially by Programme of Key New Productions of Yunnan Province,Centre of CHINA(No.2015BB002);The STS Programme of Chinese Academy of Sciences(KFJ-SW-STS-143-8);as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2015-ZZ09).; Five new ent-kaurane diterpenoids,named mascaroside Ⅲ–Ⅴ(1–3),and 20-nor-cofaryloside Ⅰ–Ⅱ(4–5),together with seven known diterpenoids,were isolated from methanol extracts of the green coffee beans of Yunnan Ara...; 关键词：Coffea arabica L. Green coffee beans DITERPENOIDS Structural elucidation

Jungermannenone A and B induce ROS- and cell cycle-dependent apoptosis in prostate cancer cells in vitro被引量：2: 《Acta Pharmacologica Sinica》2016年第6期814-824,共11页Yan-xia GUO Zhao-min LIN Mei-juan WANG Yi-wen DONG Huan-min NIU Charles YF YOUNG Hong-xiang LOU Hui-qing YUAN; Aim, Jungermannenone A and B （JA, JB） are new ent-kaurane diterpenoids isolated from Chinese liverwort Jungermannia fauriana, which show anti-proliferation activities in cancer cells. In this study we investigated t...; 关键词：jungermannenones ent-kaurane diterpenoids prostate cancer apoptosis ROS DNA damage cell cycle arrest c-Myc JNK Z-VAD vitamin C

Six new cytotoxic and anti-inflammatory 11,20-epoxy-ent-kaurane diterpenoids from Isodon wikstroemioides: 《Chinese Journal of Natural Medicines》2015年第5期383-389,共7页WU Hai-Yan WANG Wei-Guang DU Xue YANG Jin PU Jian-Xin SUN Han-Dong; supported financially by the National Natural Science Foundation of China(Nos.21322204 and 81172939);the NSFC-Joint Foundation of Yunnan Province(No.U1302223);the reservation-talent project of Yunnan Province(No.2011CI043);the West Light Foundation of the Chinese Academy of Sciences(PU JX); The present study was designed to determine the chemical constituents of Et OAc extracts of the aerial parts of Isodon wikstroemioides.Compounds 1–8 were isolated and purified by normal-phase silica gel and reversed-...; 关键词：Isodon wikstroemioides Isowikstroemins H–M CYTOTOXICITY Anti-inflammatory activity

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