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SUBCELLULAR: 作品数：101被引量：265H指数：9; 导出分析报告; 相关领域：生物学更多>>; 相关作者：李秋荣王淼赵金华陈荣礼许实波更多>>; 相关机构：中国科学院沈阳军区总医院教育部香港理工大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金重庆市自然科学基金更多>>

Optical ratiometric silica pH sensors unveil active transport and subcellular particle localization in protoplasts: 《Nano Research》2025年第3期444-457,共14页Helena Iuele Lorenzo Maria Curci Alessio Bucciarelli Valentina Onesto Stefania Forciniti Giuseppe Gigli Loretta L.del Mercato Monica De Caroli Gabriella Piro; supported by the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program ERC Starting Grant“INTERCELLMED”(Nr.759959);the Associazione Italiana per la Ricerca contro il Cancro(AIRC)(MFAG-2019,Nr.22902);the PRIN 2022(Nr.2022CRFNCP_PE11_PRIN2022 and PRIN 2022-SAPPHIRE(CUP 2022MWK7Y7);funded by European Union-Next Generation EU,the“Tecnopolo per la medicina di precisione”(TecnoMed Puglia)-Regione Puglia:DGR n.2117 of 21/11/2018,CUP B84I18000540002);the Italian Ministry of Research(MUR)in the framework of the National Recovery and Resilience Plan(NRRP),“NFFA-DI”Grant(CUP B53C22004310006);“I-PHOQS”Grant(CUP B53C22001750006);under the complementary actions to the NRRP funded by NextGenerationEU,“Fit4MedRob”Grant(PNC0000007,CUP B53C22006960001).; Understanding the interaction mechanisms of engineered nanomaterials(ENMs)with plant membranes is crucial for their effective use in various applications.While passive transport of smaller ENMs is well-documented,the ...; 关键词：optical ratiometric pH-sensors intracellular pH tracking PROTOPLAST endocytic pathway computational analysis

Mechanisms of Targeted Drug Delivery for Liver Cancer: Active, Passive, and Subcellular Strategies: 《Journal of Biosciences and Medicines》2025年第2期369-384,共16页Yang Tian Yusheng Shi; This article provides a comprehensive review of various approaches to targeted drug delivery for liver cancer, an area of significant need due to the limited effectiveness of current treatments. The article begins by ...; 关键词：Targeted Drug Delivery Hepatocellular Carcinoma (HCC) Active Targeting Subcellular Targeting NANOMEDICINE

Dark-vacuole Bodies Studying by High-resolution Label-free Microscopy Assisted with Fluorescence Technology: 《Chemical Research in Chinese Universities》2024年第6期978-986,共9页LIU Xiangyu ZHANG Jinrui XU Haijiao SHAO Lina WANG Hongda; supported by the Scientific Instrument Developing Project of the Chinese Academy of Sciences(No.ZDKYYQ20220005);the National Natural Science Foundation of China(Nos.22150003,21727816,and 21721003).; The intracellular logistics system,consisting of vesicles,plays a crucial role in cellular transport.However,there is a lack of research on the types and functions of intracellular vesicles,and new technologies are ne...; 关键词：Dark-vacuole body Subcellular Organelle LABEL-FREE Fourier ptychographic microscopy(FPM) Living cell imaging

Facile Blinking Dyes with Spontaneous Enol-Keto Tautomerism for Super-Resolution Imaging of Subcellular Targets: 《CCS Chemistry》2024年第11期2770-2782,共13页Ji Gao Weijun Wu Lulu Zhou Shaokuan Gong Chong Li Xihan Chen Yiming Li Kai Li; supported by the Ministry of Science and Technology of China(grant no.2020YFA0908900);the National Natural Science Foundation of China(grant no.U21A2097);Key Technology Research and Development Program of Shandong(grant no.2021CXGC010212);Guangdong Provincial Key Laboratory of Advanced Biomaterials(grant no.2022B1212010003);Guangdong Natural Science Foundation Joint Fund(grant no.2020A1515110380);the Shenzhen Science and Technology Program(grant nos.KQTD20200820113012029 and JCYJ20220818100416036);the start-up fund provided by SUSTech for financial support;The authors acknowledge the Center for Computational Science and Engineering at SUSTech for theoretical calculation support,and SUSTech Core Research Facilities for technical support.; Fluorophores with controlled on–off switching properties and subcellular targeting abilities are essential for modern super-resolution microscopy techniques.However,the effective design strategies of blinking fluorop...; 关键词：spontaneous enol-keto tautomerism fluorophore proton transfer fluorescence imaging subcellular target

Neural stimulation and modulation with subcellular precision by optomechanical bio-dart: 《Light(Science & Applications)》2024年第11期2668-2679,共12页Guoshuai Zhu Jianyun Xiong Xing Li Ziyi He Shuhan Zhong Junlin Chen Yang Shi Ting Pan Li Zhang Baojun Li Hongbao Xin; supported by the National Natural Science Foundation of China(12374286,62135005,12204196,and 32271405);the National Key Research and Development Program of China(2023YFF0613700);Guangdong Basic and Applied Basic Research Foundation(2022B1515120012);Science and Technology Program of Guangzhou(202201010370).; Neural stimulation and modulation at high spatial resolution are crucial for mediating neuronal signaling and plasticity,aiding in a better understanding of neuronal dysfunction and neurodegenerative diseases.However,...; 关键词：STIMULATION NEURAL precisely

A signaling cascade mediating fruit trait development via phosphorylation-modulated nuclear accumulation of JAZ repressor被引量：2: 《Journal of Integrative Plant Biology》2024年第6期1106-1125,共20页Wei Wang Jinyao Ouyang Yating Li Changsheng Zhai Bing He Huahan Si Kunsong Chen Jocelyn K.C.Rose Wensuo Jia; financially supported by the National Key Research and Development Program(2022YFD2100102);the Tianchi Talent Program(2023),the Beijing Natural Science Foundation(6232019);the National Key Research and Development Program(2019YFD1000200);the Construction of Beijing Science and Technology Innovation and Service Capacity in Top Subjects(CEFFPXM2019_014207_000032)。; It is generally accepted that jasmonate-ZIM domain(JAZ)repressors act to mediate jasmonate(JA)signaling via CORONATINE-INSENSITIVE1(COI1)-mediated degradation.Here,we report a cryptic signaling cascade where a JAZ rep...; 关键词：defense response JAZ repressor PHOSPHORYLATION strawberry subcellular translocation

Subcellular distribution of prohibitin 1 in rat liver during liver regeneration and its cellular implication: 《World Journal of Hepatology》2024年第1期65-74,共10页Qing-Ju Sun Tao Liu; BACKGROUND The function of prohibitin 1(Phb1)during liver regeneration(LR)remains relatively unexplored.Our previous research identified downregulation of Phb1 in rat liver mitochondria 24 h after 70%partial hepatecto...; 关键词：Prohibitin 1 Liver regeneration Subcellular proteomic analysis Mitochondrial stability Cell proliferation

Structural determinants specific for retromer protein sorting nexin 5 in regulating subcellular retrograde membrane trafficking: 《The Journal of Biomedical Research》2023年第6期492-506,共15页Qing Chen Meiheng Sun Xu Han Hongfei Xu Yongjian Liu; This work was supported by the National Natural Science Foundation of China(Grant Nos.31371436 and 8157051134 to Y.L.);by the laboratory start-up grant from Nanjing Medical University(to Y.L.).; The endosomal trafficking of signaling membrane proteins, such as receptors, transporters and channels, is mediated by the retromer-mediated sorting machinery, composed of a cargo-selective vacuolar protein sorting tr...; 关键词：vesicular monoamine transporter 2 SNX5 SNX6 RETROMER retrograde trafficking

Recent Progress in Endoplasmic Reticulum-Targetable Small-Molecule Probes for Fluorescence Sensing and Phototherapy: 《Journal of Analysis and Testing》2023年第3期304-324,共21页Jing Chen Huihong Liu Wenzhi Xie Maoxin Gu Guojiang Mao Sheng Yang; financial support from the National Natural Science Foundation of China(21974013);Hunan Graduate Research and Innovation Project(CX20210814);Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(2022A04);National Students’Platform for Innovation and Entrepreneurship Training Program(202210542049); The endoplasmic reticulum(ER)is the most widespread organelle within eukaryotic cells,performing various essential functions such as protein synthesis,post-translational modifications,and lipid metabolism.Abnormal flu...; 关键词：Endoplasmic reticulum Organelle-targetable fl uorescent probe Subcellular analysis Endoplasmic reticulum stress PHOTOTHERAPY

Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application: 《Journal of Pharmaceutical Analysis》2023年第7期691-693,共3页Dan Li Zhou Fang Qiang Shi Nicholas Zhang Binsheng Gong Weida Tong Ahmet F.Coskun Joshua Xu; Reducing the use of animal models in drug development and safety assessment has long been supported by the U.S.Food and Drug Administration(FDA).The report by Royal Society for the Prevention of Cruelty to Animals ind...; 关键词：MONEY utilizing testing

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