TRANSGLUTAMINASE

作品数:45被引量:36H指数:3
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相关领域:轻工技术与工程更多>>
相关作者:谭志文刘松堵国成陈坚刘龙更多>>
相关机构:浙江医药高等专科学校浙江万里学院江南大学静宜大学更多>>
相关期刊:《Journal of Wuhan University of Technology(Materials Science)》《Journal of Ocean University of China》《Cellular & Molecular Immunology》《World Journal of Dermatology》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划宁波市国际科技合作项目国家重点基础研究发展计划更多>>
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Beyond the gluten-free diet:Innovations in celiac disease therapeutics
《World Journal of Gastroenterology》2024年第38期4194-4210,共17页Sara Massironi Marianna Franchina Alessandra Elvevi Donatella Barisani 
Celiac disease(CD)is an autoimmune disorder exacerbated by the ingestion of gluten in genetically susceptible individuals,leading to intestinal inflammation and damage.This chronic disease affects approximately 1%of t...
关键词:Celiac disease Gluten tolerance Enzymatic degradation Therapeutic advances Transglutaminase inhibitors Tight junction modulators 
Transglutaminase 2 serves as a pathogenic hub gene of KRAS mutant colon cancer based on integrated analysis
《World Journal of Gastrointestinal Oncology》2024年第5期2074-2090,共17页Wei-Bin Peng Yu-Ping Li Yong Zeng Kai Chen 
Supported by National Nature Science Foundation of China,No.82100195;China Postdoctoral Science Foundation,No.2021M700777;Medical Research Project of Foshan Municipal Health Bureau,No.20230349.
BACKGROUND Colon cancer is acknowledged as one of the most common malignancies worldwide,ranking third in United States regarding incidence and mortality.Notably,approximately 40%of colon cancer cases harbor oncogenic...
关键词:Colon cancer KRAS mutation Transglutaminase 2 Weighted gene co-expression network analysis 
Identification of multiple regulatory genes involved in TGase production in Streptomyces mobaraensis DSM 40587
《Engineering Microbiology》2023年第4期20-28,共9页Xian Liu Dan Wang Yuru Zhang Xiaoxin Zhuang Linquan Bai 
supported by the National Key R&D Program of China(2021YFC2100600,2019YFA0905400);the Na-tional Natural Science Foundation of China(31830104);Science and Technology Commission of Shanghai Municipality(19430750600,19JC1413000,17JC1403600).
Microbial transglutaminase(TGase)is a protein that is secreted in a mature form and finds wide applications in meat products,tissue scaffold crosslinking,and textile engineering.Streptomyces mobaraensis is the only li...
关键词:TRANSGLUTAMINASE Streptomyces mobaraensis AdpA TRANSCRIPTION Regulatory network 
Effects of enzyme treatments on the functionality of commercial pea and pea blended protein ingredients
《Food Bioscience》2023年第3期2876-2884,共9页Y.R.Tang A.K.Stone Y.Wang Z.Jafarian L.Zhou J.Kimmel J.D.House T.Tanaka M.T.Nickerson 
support for this research was provided by Roquette America Inc;Protein Industries Canada.
The effects of enzyme treatments on the functional properties of commercial pea protein,pea:rice protein blend(3:2),pea:oat protein blend(1:1),and pea:hemp protein blend(1:1)were investigated.Treatments were applied t...
关键词:Plant protein Rice Oat HEMP PEPSIN PAPAIN TRANSGLUTAMINASE 
Transglutaminase-catalyzed modification of fish skin gelatin enhanced the protection of microcapsules to Limosilactobacillus reuteri被引量:1
《Food Bioscience》2022年第6期118-126,共9页Yulong Zhang Shuailing Guo Guiming Fu Yanru Chen Yin Wan Xiaodan Wu Ziwen Xu Jingjing Liu Zijun Xie 
supported by the fund of the National Natural Science Foundation of P.R.China(No.32060540);the Youth Talent Training Program for Academic and Technical Leaders of Major Disciplines in Jiangxi Province(No.20212BCJ23042).
In the present study,the tilapia skin gelatin was modified with Transglutaminase(TGase)to obtain wall materials with good film-forming performance.The effects of different fish skin gelatin cross-linking degree on the...
关键词:TRANSGLUTAMINASE CROSS-LINK PROBIOTICS MICROCAPSULES Simulation of digestion 
Investigating the functionality of enzymatically(transglutaminase and alcalase)treated almond protein isolate
《Food Bioscience》2022年第5期626-635,共10页Sharanya Ganesh Dian Widya Ningtyas Sangeeta Prakash 
The effects of partial hydrolysis on the functional properties of almond protein isolate(API)were investigated by treating the isolate with alcalase enzyme(2.4U/g)and a subsequent polymerization of API was studied usi...
关键词:Almond protein isolate Partial hydrolysis ALCALASE TRANSGLUTAMINASE 
Baicalein and Salvia officinalis Extract Upregulate Transglutaminase 1 mRNA Expression via the Activation of Transient Receptor Potential Channel V4
《Journal of Cosmetics, Dermatological Sciences and Applications》2022年第1期1-9,共9页Akihiro Aioi Ryuta Muromoto Tadashi Matsuda 
Background: It is important to maintain skin homeostasis for cosmetic and medical reasons. Many ceramide-related ingredients and cosmetics have been developed to improve the skin barrier function and skin hydration. S...
关键词:Transient Receptor Potential Channels Transglutaminase 1 Salvia officinalis Skin Homeostasis 
Development of a unilateral ureteral obstruction model in cynomolgus monkeys
《Animal Models and Experimental Medicine》2021年第4期359-368,共10页Linghong Huang Jia Ni Tanika Duncan Zhizhan Song Timothy S.Johnson 
This study was funded by UCB Pharma;Animal work was approved by Prisys Institutional Animal Care and Use Committee under study number 2015-PS11-002(license code SYXK-2014-007).
Background:Chronic kidney disease(CKD)has a high global prevalence and large unmet need.Central to developing new CKD therapies are in vivo models in CKD.However,next-generation antibody,protein,and gene therapies are...
关键词:animal models FIBROSIS KIDNEY nonhuman primates TRANSGLUTAMINASE 
Serologic diagnosis of celiac disease: May it be suitable for adults?
《World Journal of Gastroenterology》2021年第42期7233-7239,共7页Giuseppe Losurdo Milena Di Leo Edoardo Santamato Monica Arena Maria Rendina Carmelo Luigiano Enzo Ierardi Alfredo Di Leo 
The diagnosis of coeliac disease(CD)in adult patients requires the simultaneous assessment of clinical presentation,serology,and typical histological picture of villous atrophy.However,several years ago,the European S...
关键词:Celiac disease Villous atrophy SEROLOGY BIOPSY Anti-transglutaminase antibody 
Targeting transglutaminase 2 as a potential disease modifying therapeutic strategy for synucleinopathies
《Neural Regeneration Research》2021年第8期1560-1561,共2页Jie Zhang Hilary Grosso Jasutkar M.Maral Mouradian 
supported by grants from the Michael J. Fox Foundation for Parkinson’s Research (ID 12350);the American Parkinson Disease Association, the New Jersey Health Foundation, and by NIH grants NS101134, NS096032, and NS116921。
Synucleinopathies are a group of progressive neurodegenerative disorders characterized by the accumulation of α-synuclein(α-Syn) aggregates in Lewy bodies(LBs) and Lewy neurites(LNs) in Parkinson's disease(PD) and d...
关键词:ATROPHY THERAPEUTIC AGGREGATION 
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