MULTIDRUG-RESISTANCE

作品数：20被引量：68H指数：4
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相关领域：医药卫生更多>>
相关作者：刘福生王忠诚历俊华张亚卓张庆林更多>>
相关机构：北京市神经外科科研究所山东大学第二医院北京大学第一医院深圳大学更多>>
相关期刊：《Chinese Journal of Natural Medicines》《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《Advances in Microbiology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Peptide-based strategies for overcoming multidrug-resistance in cancer therapy
《Chinese Chemical Letters》2025年第1期110-118,共9页Xiaofang Luo Ye Wu Xiaokun Zhang Min Tang Feiye Ju Zuodong Qin Gregory J Duns Wei-Dong Zhang Jiang-Jiang Qin Xin Luan 
supported by the Science and Technology Innovation Program of Hunan Province(No.2022RC1168);National Natural Science Foundation of China(Nos.82322073,82173846,82304533);CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2023-I2M-3-009);Key project at central government level:The ability establishment of sustainable use for valuable Chinese medicine resources(No.2060302);China Postdoctoral Science Foundation(No.2021M702215);Oriental Scholars of Shanghai Universities(No.TP2022081);Jiangxi Province Thousand Talents Program(No.jxsq2023102168);Young Talent Lifting Project of China Association of Chinese Medicine(No.CACM-(2021-QNRC2-A08));Shanghai Rising-Star Program(No.22QA1409100);Shanghai Sailing Program(No.22YF1445000);2021 Shanghai Science and Technology Innovation Action Plan(No.21S11902800);Three-year Action Plan for Shanghai TCM Development and Inheritance Program(Nos.ZY(2021-2023)-0208,ZY(2021-2023)-0401);High level Key Discipline of National Administration of Traditional Chinese Medicine(No.71);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-D-202004);Innovation team of high-level local universities in Shanghai:Strategic Innovation Team of TCM Chemical Biology。
Despite ongoing advancements in cancer treatment,the emergence of primary and acquired resistance poses a significant challenge for both traditional chemotherapy and immune checkpoint blockade therapies.The demand for...
关键词：Drug resistance Antitumor peptides Mechanism of action Targeted therapeutics IMMUNOTHERAPY Medicinal chemistry 
Diarrheic Escherichia coli: A Predominant Etiological Agent of Gastroenteritis, a Case Study in Douala, Cameroon
《Journal of Biosciences and Medicines》2023年第6期1-17,共17页Amandine Plidikoua Olivier Ziem Justice T. Ngom Afsa Mamboune Balbine Adande Clémence Francioli Koro Koro Rosalie Annie Ngono Ngane 
Context: Gastroenteritis remains an infectious disease with high morbidity and mortality particularly in low incomes countries, where the capacity to search all etiological agents, especially pathogenic Escherichia co...
关键词：GASTROENTERITIS ENTEROPATHOGENS Pathogenic Escherichia coli Antibiotic Resistance MULTIDRUG-RESISTANCE 
Impact of multidrug resistance on the management of bacterial infections in cirrhosis被引量：2
《World Journal of Clinical Cases》2023年第3期534-544,共11页Carlos Terra Ângelo Zambam de Mattos Marcelo Souza Chagas Andre Torres Denusa Wiltgen Barbara Muniz Souza Renata Mello Perez 
Patients with cirrhosis have an increased risk of infection and differently from other complications,that over the years are improving in their outcomes,infections in cirrhotic patients are still a major cause of hosp...
关键词：CIRRHOSIS Infection MULTIDRUG-RESISTANCE BACTERIAL ANTIBIOTICS MICROBIOTA 
Genetic Diversity,Antibiotic Resistance,and Pathogenicity of Aeromonas Species from Food Products in Shanghai,China被引量：1
《Biomedical and Environmental Sciences》2022年第9期842-853,共12页QU Feng Tian WANG Wen Qing LIU Qian ZHOU Hai Jian HU Jin Rui DU Xiao Li WANG Yue XUE Jia Qi CUI Zhi Gang XIE Gui Lin MENG Shuang 
supported by the National Key Research and Development Program of China[grant number 2018YFC1603804]。
Objective Aeromonas has recently been recognized as an emerging human pathogen.Aeromonasassociated diarrhea is a phenomenon occurring worldwide.This study was designed to determine the prevalence,genetic diversity,ant...
关键词：AEROMONAS Genetic diversity Antibiotic resistance Virulence gene Cytotoxicity assay MULTIDRUG-RESISTANCE 
Detection of the Production of Klebsiella Pneumoniae Carbapenemase, New Delhi Metallo-Beta-Lactamase and Oxacillinase-48-Type Carbapenemases by Gram-Negative Bacilli in Resource-Limited Setting
《Advances in Microbiology》2021年第10期579-590,共12页Cecile Okalla Ebongue Gabin Gaël Simo Jean Pierre Nda Mefo’o Grace Dalle Ngondi Emmanuel Roddy Mengue Guy Pascal Ngaba Dieudonne Adiogo 
Background: The increasing resistance of bacteria to various antibiotics is a worldwide public health issue. Carbapenems that have elicited great hope in treating infections caused by multidrug-resistant germs ...
关键词：CARBAPENEMASES Gram-Negative Bacilli MULTIDRUG-RESISTANCE Cameroon 
Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p被引量：4
《Science Bulletin》2021年第18期1895-1905,M0004,共12页Yaojun Tong Jingyu Zhang Nuo Sun Xiang-Ming Wang Qi Wei Yu Zhang Ren Huang Yingying Pu Huanqin Dai Biao Ren Gang Pei Fuhang Song Guoliang Zhu Xinye Wang Xuekui Xia Xiangyin Chen Lan Jiang Shenlin Wang Liming Ouyang Ning Xie Buchang Zhang Yuanying Jiang Xueting Liu Richard Calderone Fan Bai Lixin Zhang Gil Alterovitzk 
supported by the National Key Research and Development Program of China (2020YFA0907800);the National Natural Science Foundation of China (31720103901);the “111” Project of China (B18022);the Fundamental Research Funds for the Central Universities (22221818014S);the Open Project Funding of the State Key Laboratory of Bioreactor Engineering,the Shandong Taishan Scholar Award,and the Novo Nordisk Foundation (NNF10CC1016517)。
Clinical use of antimicrobials faces great challenges from the emergence of multidrug-resistant pathogens. The overexpression of drug efflux pumps is one of the major contributors to multidrug resistance(MDR). Reversi...
关键词：Candida albicans BERBERINE MULTIDRUG-RESISTANCE Drug excretion transporter MITOCHONDRIA 
Determination of Fusidic Acid Susceptibility of Multidrug-resistant Gonococcal Isolates from China被引量：1
《Infectious Microbes & Diseases》2019年第2期70-74,共5页Fan Yang Stijn van der Veen 
This work was supported by the Zhejiang Provincial Natural Science Foundation of China(grant number LR16H190001).
The currently recommended gonococcal therapies are rapidly losing efficacy and;therefore,novel options for treatment are urgently required to ensure future treatment remains available.Here we investigated the suscepti...
关键词：fusidic acid MULTIDRUG-RESISTANCE Neisseria gonorrhoeae 
Expression of multidrug-resistance associated proteins in human retinoblastoma treated by primary enucleation被引量：3
《International Journal of Ophthalmology(English edition)》2018年第9期1463-1466,共4页Li-Juan Tang Li-Jun Zhou Wen-Xin Zhang Jian-Yan Lin Yong-Ping Li Hua-Sheng Yang Ping Zhang 
Supported by the National Natural Science Foundation of China(No.30371515)
AIM： To reveal the expression of multidrug-resistance associated proteins： glutathione-S-transferase π（GSTπ）, P-glycoprotein（P-gp） and vault protein lung resistance protein（LRP） in retinoblastoma（RB） witho...
关键词：glutathione-S-transferase π P-GLYCOPROTEIN vault protein lung resistance protein RETINOBLASTOMA multidrug-resistance proteins 
Prevalence and characteristics of extended spectrum β-lactamase-producing Escherichia coli from bovine mastitis cases in China被引量：2
《Journal of Integrative Agriculture》2018年第6期1246-1251,共6页YANG Feng ZHANG Shi-dong SHANG Xiao-fei WANG Xu-rong WANG Ling YAN Zuo-ting LI Hong-sheng 
funded by the National Key R&D Program of China (2017YFD0502200);the Central PublicInterest Scientific Institution Basal Research Fund,China (1610322017013)
The aim of the study was to investigate the prevalence and characterization of extended-spectrum β-lactamase （ESBL）- producing Escherichia coli isolated from bovine mastitis cases in China. ChromID ESBL agar was us...
关键词：extended spectrum β-lactamase Escherichia coli MULTIDRUG-RESISTANCE bovine mastitis 
High prevalence of multidrug-resistance in Acinetobacter baumannii and dissemination of carbapenemase-encoding genes bla_(OXA-23-like),bla_(OXA-24-like)and bla_(NDM-1) in Algiers hospitals被引量：20
《Asian Pacific Journal of Tropical Medicine》2015年第6期439-447,共9页Khadidja Khorsi Yamina Messai Moufida Hamidi Houria Ammari Rabah Bakour 
supported by grants from National Fund for the Research and National Agency for the Development of Research in Health(Algeria)
Objective:To assess and characterize antibiotic resistance in Acinetobacter baumannii strains recovered from 5 health-care facilities in Algiers.Methods:Antibiotic susceptibility testing was performed by agar diffusio...
关键词：Acinetobacter baumannii MULTIDRUG-RESISTANCE CARBAPENEMASE bla_(OXA-23-like) bla_(OXA 24 like) bla_(NDM-1) carO Hospital Algiers 
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