GINKGOLIDES

作品数：12被引量：55H指数：4
导出分析报告
相关领域：医药卫生更多>>
相关作者：冯高谦张磊黄沛力杜泽英李晓玉更多>>
相关机构：首都医科大学中国科学院南京工业大学江苏大学更多>>
相关期刊：《Acta Biochimica et Biophysica Sinica》《Chinese Journal of Chemical Engineering》《分析测试学报》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金天津市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
DGMI alleviates OGD/R-induced cell injury by regulating inflammatory and apoptosis signaling pathways被引量：5
《Journal of Chinese Pharmaceutical Sciences》2020年第7期455-469,共15页Qian Hong Zenghui Wang Yang Yang Lu Gao Zhao Yan 
Diterpene ginkgolides meglumine injection(DGMI),a kind of Ginkgo biloba special extract injection,is now used for the treatment of ischemic stroke in convalescence.In the present study,we aimed to confirm whether DGMI...
关键词：GINKGOLIDES BV2 microglia cells TLR Cerebral ischemia NF-κB MAPK Inflammation 
Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice
《Acta Pharmacologica Sinica》2019年第2期192-198,共7页Xiao-fang Huang Song-zhao Zhang Ya-yu You Na Zhang Hong Lu Alan Daugherty Xiao-jie Xie 
Abdominal aortic aneurysms (AAAs) are a chronic vascular disease characterized by pathological luminal dilation. Aortic rupture is the fatal consequence of AAAs. Ginkgo biloba extracts (GBEs), a natural herb extract w...
关键词：ABDOMINAL aortic ANEURYSM ANGIOTENSIN HYPERCHOLESTEROLEMIA GINKGO biloba extracts flavonoids GINKGOLIDES 
Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling被引量：29
《Acta Pharmacologica Sinica》2018年第8期1259-1272,共14页Wen ZHANG Jun-ke SONG Rong YAN Li LI Zhi-yong XIAO Wen-xia ZHOU Zhen-zhong WANG Wei XIAO Guan-hua DU 
This work was supported by grants from the National Science and Technology Major Projects for ＂Major New Drugs Innovation and Development＂ （No 2013ZX09402203）; the National Natural Science Foundation of China （No 81603100）; the Graduate Student Innovation Fund of the Chinese Academy of Medical Sciences and Peking Union Medical College （No 2015-1007-07）; the Open Project of the State Key Laboratory of Toxicology and Medical Countermeasures （No TMC201510）; and The CAMS Innovation Fund for Medical Sciences （No 2017-I2M-1-010）.
Diterpene ginkgolides meglumine injection （DGMI） is a therapeutic extract of Ginkgo biloba L, which has been used for the treatment of cerebral ischemic stroke in China. Ginkgolides A, B and C are the main component...
关键词：cerebral ischemia diterpene ginkgolides PI3K Akt NRF2 HO-1 CREB LY294002 
Pharmacokinetics of the prototype and hydrolyzed carboxylic forms of ginkgolides A, B, and K administered as a ginkgo diterpene lactones meglumine injection in beagle dogs被引量：9
《Chinese Journal of Natural Medicines》2017年第10期775-784,共10页WANG Shu-Yao A Ji-Ye FEI Fei GENG Jian-Liang PENG Ying OUYANG Bing-Chen WANG Pei JIN Xiao-Liang ZHAO Yu-Qing WANG Jian-Kun GENG Ting LI Yan-Jing HUA NG Wen-Zhe WANG Zhen-Zhong XIAO Wei WANG Guang-Ji 
financially supported by the National Key Special Project of Science and Technology for Innovation Drugs of China(Nos.2013zx09402203 and 2013zx09402202);the Natural Science Foundation of Jiangsu Province,China(No.BK20130403);the National Natural Science Foundation of China(No.81503342);the Project for Jiangsu Province Key Lab of Drug Metabolism and Pharmacokinetics(No.BM2012012)
Ginkgo diterpene lactones meglumine injection(GDLI)is a commercially available product used for neuroprotection.However,the pharmacokinetic properties of the prototypes and hydrolyzed carboxylic forms of the primary c...
关键词：Hydrolysates of GINKGOLIDES LC-MS/MS PHARMACOKINETICS GINKGO DITERPENE LACTONES Beagle dog 
Ginkgolides protects cultured cortical neurons against excitotoxic and oxidative insults
《中国药理通讯》2004年第2期20-22,共3页ZHANGYu-Yang YUQing-Hai YOUSong SHENGLi 
AIM: The neurotoxicity of glutamate is associated with neurological disorders including hypoxic-ischaemic brain injury. Studies using cultured cortical neurons have demonstrated that exposure to glutamate produced del...
关键词：保护作用 大脑皮层 神经刺激 抗氧化作用 神经元 
Partial Abstracts of East China Symposium of Biochemistry ＆ Molecular Biology-2003 （Part Ⅱ）——Signal Transduction Pathway of the Protective Effects of Ginkgolides on Chemical Hypoxia Injury to CorticalNeurons被引量：1
《Acta Biochimica et Biophysica Sinica》2004年第2期163-163,共1页LiZHU YeZHANG Hong-ShanCHEN Shu-YiJIN 
Ginkgolides (Gin), mainly including A, B, C, J, M and belonging to terpene lactone are one of the main active constituents in the extractof leaves of Ginkgo biloba L. Gin B is a specific and potent antagonist of plate...
GC-MS测定家犬血浆中银杏内酯A、B的含量被引量：6
《分析测试学报》2004年第z1期24-25,共2页黄沛力 秦亚萍 冯高谦 张磊 
　　银杏叶制剂作为治疗和预防动脉粥样硬化的有效药物,越来越为人们关注.银杏叶成分复杂,其中银杏黄酮具有扩张血管,降血脂,改善微循环的作用;银杏内酯是血小板活化因子强拮抗剂,对免疫系统,中枢神经系统,缺血损伤有保护作用,并有抗休...
关键词：Gas chromatography - mass spectrometry GINKGOLIDES Plasma 
Isolation and Preparative Purification for Ginkgolides A and B被引量：1
《Chinese Journal of Chemical Engineering》2003年第2期125-129,共5页韩金玉 王华 常贺英 褚巧伟 
Supported by the Natural Science Foundation of Tianjin(No.993606911).
In this paper a simple preparative method for isolation and purification of ginkgolides A and B was developed,As starting material,a commercially available standardized ginkgo extract (EGb761,containing 24% flavonoid ...
关键词：ginkgolide A ginkgolide B isolation and purification uniform design preparative liquid chromatog-raphy 
High Performance Liquid Chromatography-Electrospray Ionization-Mass Spectrometric Analysis of Bilobalide and Ginkgolides in Ginkgo biloba L. Leaves被引量：1
《Journal of Chinese Pharmaceutical Sciences》2002年第2期26-30,共5页卢定强 韦萍 欧阳平凯 陈钧 
The ginkgo terpenoids including bilobalide and ginkgolides are the main pharmaceutical components in the leaves or extracts of Ginkgo biloba L. In this paper, the analysis of bilobalide and ginkgolides in leaves of Gi...
关键词：High performance liquid chromatography Electrospray ionization Mass spectrometry Ginkgo terpene lactones 
THE APPLICATION OF A NOVEL ADSORBENT IN RAPID SAMPLE CLEAN-UP OF GINKGOLIDES AND BILOBALIDE IN EXTRACTS OF GINKGO BILOBA LEAVES
《Chinese Journal of Reactive Polymers》2000年第1期60-66,共7页XUMingcheng XUMancai SHI Zuoqing LIU Juxiang SHIRongfu HE Binglin 
Supported by the National Natural Science Foundation of China !(Grant No. 29574164)
A rapid method has been developed for rapid sample clean-up in the determination of the pharmocologically active terpenoid including ginkgolide A, B. C and bilobalide in ginkgo biloba leaves extracts (GBE). The extrac...
关键词：Ginkgo biloba. Ginkgolide BILOBALIDE Hydrogen bonding High-performance liquid chromatography 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部