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supported by the Fundamental Research Funds for the Central Universities;National Natural Science Foundation of China(Grant No.12271272)。
With the advancement of modern scientific research,multimodal data is increasingly being collected from multiple sources or types.For outcomes derived from generalized linear models with high-dimensional and multimoda...
National Major Scientific and Technological Special Project for“Significant New Drugs Development”:Clinical Value Prescription Discovery and Evaluation Technology Based on Modular Pharmacology(No.2017ZX09301059);the Joint Innovation Project of China Academy of Chinese Medical Sciences:Study on the Mechanism of Action of Neuronal Regenerative Function Module Activated by Qingkailing Components(No.ZZ11-026);the University Collaborative Innovation Project of Anhui:Creation of a Combined Animal Model of Coronary Heart Disease Based on the Theory of Xin'an Medicine(No.GXXT-2020-024);the University Natural Science Research Project of Anhui Province:Molecular Mechanism of the Anti-hepatic Fibrosis Effect of Wickerwork Amide Based on the Regulation of Intercellular Communication by PTRF(No.2023AH051752)。
OBJECTIVE:To explore the functional role of the drugdependent mesenchymal-epithelial transition(Met)-axiation"π"structural module of neurogenesis after processing by three components of Qingkailing injection in neuro...
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(2022R1F1A1062699).
Haloarchaea represents a unique group of microorganisms that have adapted to thrive in high-salt environments.These microbes produce distinctive biomolecules,some of which exhibit extraordinary properties.One such bio...
Two recent cryo-EM publications in Nature by Su et al.and Yamaguchi et al.have captured snapshots of structures of Drosophila Dicer-2 bound to target dsRNA in the presence of protein cofactors Loquacious-PD or R2D2 al...
Supported by National Natural Science Foundation of China(No.81570891);Beijing Natural Science Foundation(No.7151003)。
AIM: To measure the concentration of vascular endothelial growth factor-A(VEGF-A), and placental growth factor(PLGF) in aqueous humor of uveal melanoma patients before and after Iodine-125 plaque therapy(IPT), determi...
Background: Diabetic retinopathy (DR) is a common complication of diabetes mellitus and a major cause of vision loss in the working age population. Its pathogenesis is poorly understood but may involve low grade chron...
supported by the National Nature Science Foundation of China(Nos.31171327 and 81770377);the Nature Science Foundation of Hubei Province(No.2017CFB448).
To investigate the effect of Myocardin related transcription factor A(MRTF-A)on apoptosis induced by ischemic/reperfusion(I/R),middle cerebral artery occlusion/reperfusion(MCAO/R)in rats were applied to mimic I/R.The ...
The anthors thank the support from Tianjin Philosophy and Social Science Planning Project(No.TJYYQN19-004);Project of National and Regional Research Center,Ministry of Education(No.ZX20170183);National Natural Science Foundation Youth Project(No.71803089).
Since 2002,the People's Bank of China has frequently used both quantity-based direct monetary instruments and price-based indirect monetary instruments to promote economic growth and stabilize price level.Specifically...
AIM: To study polymorphisms in promotor regions of tumor necrosis factor(TNF)-α TNF-863 A/C(rs1800630), TNF-308 A/G(rs1800629), and TNF-238 A/G(rs361525) in patients with age-related macular degeneration(AMD) and ass...
Supported by Grants from the Fundamental Research Funds for the Central Universities,No.2013JDHZ08;Personnel training Specialized Research Fundation of The Second Affiliated Hospital of Xi’an Jiaotong University of China,No.RC(GG)201404
AIM: To evaluate preventative effects of ischemic preconditioning(IP) in a rat model of intestinal injury induced by ischemia-reperfusion(IR).METHODS: Male Sprague-Dawley rats(250-300 g) were fasted for 24 h with free...