BERBAMINE

作品数：20被引量：78H指数：7
导出分析报告
相关领域：医药卫生更多>>
相关作者：李金鸣常天辉王玉萍崔宏刘东举更多>>
相关机构：北京农林科学院中国医科大学附属第一医院中国医科大学中国医学科学院北京协和医学院更多>>
相关期刊：《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein被引量：4
《Acta Pharmaceutica Sinica B》2022年第12期4378-4389,共12页Dongrong Yi Quanjie Li Han Wang Kai Lv Ling Ma Yujia Wang Jing Wang Yongxin Zhang Mingliang Liu Xiaoyu Li Jianxun Qi Yi Shi George F.Gao Shan Cen 
This research was funded by the CAMS Innovation Fund for Medical Sciences(Grant Nos.2021-I2M-1-030 and CAMS-I2M-1-012,China);the National Natural Science Foundation of China(Grant Nos.81802019,81902075 and 81673358);the National Mega-project for Innovative Drugs(Grant No.2018ZX09711003-002-002,China);the Beijing Natural Science Foundation(Grant No.7184228,China);the Peking Union Medical College Youth Fund(Grant Nos.3332016063 and 3332018096,China);the China Ministry of Science and Technology National 973 Project(Grant No.2014CB542503);the Excellent Young Scientist Program from the NSFC(Grant No.81622031,China);the National Key Research and Development program of China(Grant No.2016YFD0500307).
Ebola virus(EBOV)infection leads to staggeringly high mortality rate.Effective and low-cost treatments are urgently needed to control frequent EBOV outbreaks in Africa.In this study,we report that a natural compound c...
关键词：Ebola virus Drug repositioning Entry inhibitor Primed glycoprotein Structure-based virtual screening Protein-protein interaction Berbamine hydrochloride Natural compound 
Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2被引量：2
《Signal Transduction and Targeted Therapy》2021年第5期1433-1435,共3页Lihong Huang Terrence Tsz-Tai Yuen Zuodong Ye Shuyan Liu Guoliang Zhang Hin Chu Jianbo Yue 
This work was supported by Hong Kong Research Grant Council(RGC)grants(11101717 and 11103620),NSFC(21778045 and 32070702);Shenzhen government research grant(JSGG20200225150702770).
Dear Editor,Middle East respiratory syndrome-related coronavirus(MERS-CoV)is the pathogen responsible for the outbreak of MERS,and we are currently being affected by coronavirus disease 2019(COVID-19)due to infection ...
关键词：ACE2 INFECTION RESPIRATORY 
Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation in mice被引量：9
《Chinese Journal of Natural Medicines》2020年第3期186-195,共10页LIU Xin-Yu CHEN Guan-Nan DU Guo-Ming PAN Yue SONG Wu-Qi JIANG Ting-Wang LIU Hai-Liang 
National Natural Science Foundation of China(NSFC)(No.81701573);Key Technologies of Prevention and Control for Major and Infectious Diseases Project of Suzhou(No.GWZX201604);Youth Medical Talent Project of Jiangsu(No.QNRC2016214)。
Alcoholic liver disease(ALD) has become one of the leading causes of death in the world. Berbamine(BM), a natural product mainly derived from Berberis vulgaris L, possesses multiple bioactivities as a traditional medi...
关键词：BERBAMINE ETHANOL HEPATIC INJURY NF-κB INFLAMMATION 
Berbamine suppresses cell proliferation and promotes apoptosis in ovarian cancer partially via the inhibition of Wnt/β-catenin signaling被引量：11
《Acta Biochimica et Biophysica Sinica》2018年第6期532-539,共8页Heng Zhang Yunping Jiao Chunyang Shi Xiao Song Ying Chang Yong Ren Xiaolin Shi 
Ovarian cancer is a common and lethal cancer affecting women globally. Berbamine is a natural compound from the plant Berberis amurensis, which is used in Chinese traditional medicine. Recent studies have shown the an...
关键词：ovarian cancer BERBAMINE cell proliferation apoptosis WNT/Β-CATENIN 
Identification of berbamine dihydrochloride from barberry as an anti-adipogenic agent by high-content imaging assay被引量：2
《Journal of Traditional Chinese Medical Sciences》2016年第2期91-99,共9页Shifeng Wang Qiao Zhang Yuxin Zhang Yanling Zhang Qinghua Wu Shiyou Li Yanjiang Qiao 
This work was supported by a grant from the National Natural Science Foundation of China(grant number 81430094).
Objective:Lipid droplet(LD)deposition in adipose tissue is a critical factor leading to metabolic dysfunction.Various herbal medicines in traditional Chinese medicine(TCM)are used to treat hyperlipidemia,type 2 diabet...
关键词：3T3-L1 adipocyte Berbamine dihydrochloride HEPATOTOXICITY High content screening Lipid droplet 
Roles of berbamine in the normal and ischemia/reperfusion hearts
《中国药理学通报》2015年第B11期199-200,共2页
Myocardial infarction resulting from coronary atherosclerosis is the leading cause of death in modern soci- ety. Reperfusion is an essential treatment to salvage ischemia myocardium from necrosis, while it also leads ...
关键词：MYOCARDIAL INFARCTION BERBAMINE POSTCONDITIONING AUTOPHAGY ISCHEMIA/REPERFUSION injury 
Emerging role of berbamine as an anti-cancer agent in systemic malignancies besides chronic myeloid leukemia被引量：1
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2012年第9期761-762,共2页Shailendra KAPOOR 
The recent article by Liang et al. （2011）, pub- lished in Journal of Zhejiang University-SCIENCE B （Biomedicine ＆ Biotechnology）, is highly interesting. Interestingly, the past few years have seen the in- creasin...
关键词：CLC number  R55 
New Collection of Crude Drugs in Chinese Pharmacopoeia 2010 II.Sankezhen(Berberis spp.)被引量：3
《Chinese Herbal Medicines》2011年第4期268-284,共17页DAN Yang1,LIU Yan-ze1,PENG Yong1,QIAN Zhong-zhi2,XIAO Pei-gen1 1.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Beijing 100193,China 2.Chinese Pharmacopoeia Commission,Beijing 100061,China 
Sankezhen(Berberidis Radix)is a traditional Chinese materia medica,cold in nature and bitter in taste,for treating syndromes of liver,stomach,and large intestinal meridians,in which berberine and berbamine are the maj...
关键词：ALKALOIDS Berberidis Radix BERBERINE BERBAMINE Chinese Pharmacopoeia ETHNOPHARMACOLOGY 
Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity被引量：7
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2011年第7期568-574,共7页Yun LIANG Xi QIU Rong-zhen XU Xiao-ying ZHAO 
Project supported by the National Natural Science Foundation of China (No. 30873095);the Natural Science Foundation of Zheji-ang Province, China (No. 491020-N20529)
Objective: The cytotoxic effect of berbamine on chronic myeloid leukemia (CML) cell line KU812 was evaluated,and the mechanisms of its action were explored.Methods: The effect of berbamine on the KU812 cell growth was...
关键词：BERBAMINE APOPTOSIS SMAD3 KU812 cells 
Berbamine, a novel nuclear factor κB inhibitor, inhibits growth and induces apoptosis in human myeloma cells被引量：17
《Acta Pharmacologica Sinica》2009年第12期1659-1665,共7页Yun LIANG Rong-zhen XU Lei ZHANG Xiao-ying ZHAO 
Aim： We sought to investigate the effect of berbamine on the growth of human multiple myeloma cell line KM3 and elucidate the mechanism of its action. Methods： MTT assay was used to determine the inhibitory effect o...
关键词：BERBAMINE multiple myeloma nuclear factor-kappa B APOPTOSIS 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部