METABOLOMIC

作品数:175被引量:496H指数:12
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相关领域:医药卫生更多>>
相关作者:张哲毕惠嫦杨宇卓赵一懿傅欣彤更多>>
相关机构:中山大学北京大学第三医院北京市药品检验所华中农业大学更多>>
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相关基金:国家自然科学基金高等学校学科创新引智计划中国博士后科学基金上海市自然科学基金更多>>
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Metabolomic reveals the inhibition mechanism of proline on hexanal production in chicken meat
《Food Science and Human Wellness》2025年第2期662-670,共9页Huanxian Cui Yuxi Jin Yanke Wang Xiaoya Yuan Li Liu Jie Wen Guiping Zhao 
funded by grants from the State Key Laboratory of Animal Nutrition(2004DA125184G2109);Basic Research from Chinese Academy of Agricultural Sciences(Y2019XK06);the Agricultural Science and Technology Innovation Program(ASTIP-IAS04);the Earmarked Fund for Modern Agro-Industry Technology Research System(CARS-41)。
Hexanal contributes significantly to meat flavor.The aim of this study was to identify the metabolic pathways of hexanal formation in chicken meat.We found 32 metabolites associated with hexanal content in chicken mea...
关键词:FLAVOR Amino acids Fatty acids Negative regulation Pyrimidine metabolism pathway 
A multi-omics analysis of viral nucleic acid poly(I:C)responses to mammalian testicular stimulation
《Stress Biology》2024年第1期680-691,共12页Donghui Yang Wenping Wu Qizhong Lu Yaling Mou Wenbo Chen Shicheng Wan Mengfei Zhang Congliang Wang Xiaomin Du Na Li Jinlian Hua 
supported by the National Natural Science Foundation of China(32072806,20230978);the National Key Research and Development Program of China(2022YFD1302201,2023YFF1000904,2023ZD0404303);Xinjiang Ugur Autonouous Region Scientific Research and Innovation Platform Construction Project“State Key Laboratory of Genetic Improvement and Germplasm Innovation of Grass-fed Livestock Coconstruction by the Province and Ministry”,Key Technologies Demonstration of Animal Husbandry in Shaanxi Province(20221086,20230978);Inner Mongolia Autonomous Region posted leaders(2022JBGS0025).
The male reproductive system has a standard immune response regulatory mechanism,However,a variety of external stimuli,including viruses,bacteria,heat,and medications can damage the testicles and cause orchitis and ep...
关键词:ORCHITIS Poly(I:C) Proteomic METABOLOMIC Homeostasis 
Liver metabolomic characteristics in three different rat models of Yin deficiency based on ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry
《Journal of Traditional Chinese Medicine》2023年第2期274-285,共12页HU Xingyao LIU Hongning YAN Xiaojun CHEN Zhong FU Liu LIU Ge CHEN Xuan SHANG Guangbin 
Supported by Jiangxi University of Chinese Medicine,Jiangxi Province Double First-Class Discipline of Traditional Chinese Medicine Construction Project (No. JXSYLXK-ZHYI026);Supported by Science and Technology Program of Jiangxi Provincial Health and Health Commission (SKJP220210415):Exploring the Formation Mechanism of Liver and Kidney Yin Deficiency Based on Animal Model and Metabolomics;Supported by National TCM Leading Talent Support Program of the State Administration of TCM-Qi Huang Scholar (No. 284, China TCM people’s teaching letter [2018])。
OBJECTIVE:To investigate the mechanism of Yin deficiency syndrome(YDS) by analyzing the liver metabolomic characteristics of three different Yin deficiency rat models METHODS:Following the TCM etiology,for clinical fe...
关键词:molecular biology integrative medicine Yin deficiency syndrome syndrome complex 
Metabolomic Profiling of Mice Exposed toα-amanitin Using Ultra-performance Liquid Chromatography Quadrupole Time-of-flight Tandem Mass Spectrometry
《Biomedical and Environmental Sciences》2023年第3期289-294,共6页LI Lei ZHENG Chong YE Jian Fang ZHU Kai ZHOU Yi Bing LIU Jia GAO Ming WU Yu Tian LIU Yong Ting LIU Li Ya LIN Ye LI Hai Chang ZHANG Quan GUO Hua 
financially supported by Guizhou Provincial Science and Technology Support Program[No.Qiankehe[2021]496];Science and Technology Fund of Guizhou Health Commission[No.gzwkj2021-407];National Major Research Project[No.2017YFC1601805];Guizhou Provincial Science and Technology Support Program[No.Qiankehe[2017]2972]。
Numerous instances of poisoning caused by the ingestion of mushrooms are reported annually worldwide,with most mushroom poisoning deaths caused by the ingestion of toxic amanita fungi.Amatoxin is the main toxic compon...
关键词:Metab ani annually 
Non-targeted cellular metabolomics revealing the metabolomic features and anti-tumor mechanisms of cyanidin-3-O-arabinoside on Caco-2 cells
《Food Bioscience》2023年第1期827-836,共10页Ge Xu Wenjun Xue Dan Zhang Zhipeng Yu Jingbo Liu Wenzhu Zhao 
supported by The China Scholarship Council(Grant No.202008210142);the Open Fund of Key Laboratory of Fruit and Vegetable Processing,Ministry of Agriculture and Rural Affairs,China(Grant No.FVKF2020002).
Cyanidins are considered the most widespread anthocyanin in nature,and the cyanidin-3-O-arabinoside from apple with anti-tumor activity has been screened in our previous study.However,the anti-tumor mechanism of cyani...
关键词:Cyanidin-3-O-arabinoside Caco-2 cell ANTI-TUMOR Metabolomics 
Linalool against Hafnia alvei,its antibacterial mechanism revealed by metabolomic analyses被引量:3
《Food Bioscience》2023年第1期858-868,共11页Luyao Gao Haiming Chen Wenxue Chen Weijun Chen Haoyu Jian Qiuping Zhong Ming Zhang 
the National Natural Science Foundation of China(No.32160591)for financial support.
Linalool,a major component of aromatic plant essential oils,has an antibacterial effect against Hafnia alvei,which can induce food spoilage.In this study,we aimed to investigate the antibacterial effect and mechanism ...
关键词:LINALOOL Hafnia alvei Antibacterial mechanism Metabolomics Respiratory metabolism Energy metabolism 
Study on inoculation fermentation by fungi to improve the taste quality of summer green tea
《Food Bioscience》2023年第1期959-966,共8页Jinjie Du Xinhui Wu Shili Sun Yuna Qin Kaibin Liao Xiaochun Liu Ruijin Qiu Zhirong Long Lingzhi Zhang 
supported by the following project funds:1.Liupao tea processing technology optimization supported by Wuzhou Academy of Agricultural Sciences(No.H20496);supported by Wuzhou Tea Industry Development Service Center(No.H220644),Wuzhou 543003,China。
Summer green tea(SGT)is not favored by consumers due to its strong bitterness and astringency.This study aims to improve the taste of SGT using tea-derived fungi isolated from Liupao tea by solid-state fermentation.Ba...
关键词:Summer green tea FUNGUS Inoculation fermentation Taste quality METABOLOMIC 
Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds
《Integrative Zoology》2022年第6期1162-1178,共17页Ying XIONG Yan HAO Yalin CHENG Liqing FAN Gang SONG Dongming LI Yanhua QU Fumin LEI 
funded by the National Natural Science Foundation of China(Nos.3213000355,31630069 to F.L.);the Second Tibetan Plateau Scientific Expedition and Research(STEP)program(Grant No.2019QZKK0304 to F.L.).
Pectoralis phenotypic variation plays a fundamental role in locomotion and thermogenesis in highland birds.How-ever,its regulatory and metabolic mechanisms remain enigmatic to date.Here,we integrated phenomic,tran-scr...
关键词:ALTITUDE gas chromatography–mass spectrometry HYPOXIA pectoralis RNA–seq 
Genomic and metabolomic analysis of Bacillus licheniformis with enhanced poly-γ-glutamic acid production through atmospheric and room temperature plasma mutagenesis
《Frontiers of Chemical Science and Engineering》2022年第12期1751-1760,共10页Xiaoyu Wei Lijie Yang Haiyan Wang Zhen Chen Yiyuan Xu Yue Weng Mingfeng Cao Qingbiao Li Ning He 
This work was financially supported by the National Natural Science Foundation of China(Grant Nos.32170061 and 31871779).
Poly-γ-glutamic acid is an extracellular polymeric substance with various applications owing to its valuable properties of biodegradability,flocculating activity,water solubility,and nontoxicity.However,the ability o...
关键词:ARTP mutagenesis Bacillus licheniformis poly-γ-glutamic acid metabolomics 
Proteomic and metabolomic analyses provide insight into the off-flavour of fruits from citrus trees infected with‘Candidatus Liberibacter asiaticus’被引量:1
《Horticulture Research》2019年第1期1405-1417,共13页Lixiao Yao Qibin Yu Ming Huang Weilun Hung Jude Grosser Shanchun Chen Yu Wang Frederick G.GmitterJr. 
supported by the Florida Citrus Research and Development Foundation(CRDF);the Earmarked Fund for China Agriculture Research System(CARS-27),and China Scholarship Council.
Orange fruit from trees infected by‘Candidatus Liberibacter asiaticus’(CaLas)often do not look fully mature and exhibit off-flavours described as bitter,harsh,and metallic rather than juicy and fruity.Although previ...
关键词:orange INSIGHT absolute 
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