This work was supported by the Key Research Project of Hainan Province(grant No.ZDYF2019141,No.ZDYF2018113);the Scientific research projects of health and family planning industry in Hainan Province(grant No.20A200501).
Objective:To provide reference of pharmaceutical care for the clinical treatment of a severe patient with antibiotic-associated encephalopathy.Methods:Clinical pharmacists participated in the clinical treatment of the...
supported by the National Natural Science Foundation of China(Nos.81874324,81473280,U1608283,81603186)
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam,renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats.A b...
Supported by Education Department of Henan Province Item(2006230004);Henan Science and Technology Agency Item(072102130009)~~
[Objective] Ceftiofur was as the substrate to induce the standard strain of Escherichia coli(E.coli)to be the drug-resistance one.The resistant mechanism of E.coli to ceftiofur was studied.[Method] The sub-inhibitor...
A reversed-phase high performance liquid chromatographic (RP-HPLC) method wasdeveloped and validated for the simultaneous deteimination of ceftazidime and tazobactam ininject-able powder. Methods Chromatography was ca...
Tazobactam,β lactamase inhibitor, was synthesized from 6 aminopenicillanic acid through eleven steps, including diazotization, bromination, oxidation, chlorization, cyclization, deprotection and so on. The designed...