OUTGROWTH

作品数：48被引量：301H指数：8
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相关领域：医药卫生生物学更多>>
相关作者：杨允段恩奎曾国庆曹宇静王新春更多>>
相关机构：哈尔滨医科大学附属第二医院中国科学院复旦大学中南大学更多>>
相关期刊：《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《Soft Nanoscience Letters》《American Journal of Molecular Biology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划上海市自然科学基金广东省自然科学基金更多>>
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Proliferative potential and angiogenic characteristics of blood outgrowth endothelial cells derived from middle-aged and older adults
《Journal of Geriatric Cardiology》2024年第11期1071-1084,共14页Xue-Juan XIA Xuan-Yu CHEN Lin-Lin XIAO 
sponsored by Shanghai Pujiang Program(23PJ1409600);Intergovernmental International Science and Technology Innovation Cooperation Key Project of Chinese National Key R&D Program(2024YFE0102600);Singapore Ministry of Education Academic Research Fund Tier 1(R160-000-A26–114).
Objectives Autologous blood outgrowth endothelial cells(BOECs)have been proposed to induce therapeutic angiogenesis for treating cardiovascular diseases(CVDs).The aim of the present study was to investigate the prolif...
关键词：HEALING PASSAGE CHARACTERISTICS 
Brassinosteroid Biosynthetic Gene CmDWF4 Regulates Bud Outgrowth in Chrysanthemum morifolium
《Phyton-International Journal of Experimental Botany》2023年第6期1681-1694,共14页Xianrong Fu Aiping Song Bo Peng Song Li Weixin Liu Lingling Zhang Jiafu Jiang Sumei Chen Fadi Chen 
This research was funded by the National Natural Science Foundation of China(31872149,32172609);China Agriculture Research System(CARS-23-A18),the“JBGS”Project of Seed Industry Revitalization in Jiangsu Province(JBGS[2021]020);the earmarked fund for Jiangsu Agricultural Industry Technology System,and a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Brassinosteroids(BRs),a class of steroid phytohormones,play a critical role in plant growth and development.The DWF4 gene encodes a cytochrome P450 enzyme(CYP90B1),which is considered a rate-limiting enzyme in BR bios...
关键词：BR axillary bud shoot branching XTHs cell elongation 
IQ67 DOMAIN protein 21 is critical for indentation formation in pavement cell morphogenesis
《Journal of Integrative Plant Biology》2023年第3期721-738,共18页Xinhua Feng Shujuan Pan Haifu Tu Junjie Huang Chuanlei Xiao Xin Shen Lei You Xinyan Zhao Yongqiang Chen Danyun Xu Xiaolu Qu Honghong Hu 
supported by funding from the National Natural Science Foundation of China (31970730, 32170721)。
In plants, cortical microtubules anchor to the plasma membrane in arrays and play important roles in cell shape. However, the molecular mechanism of microtubule binding proteins, which connect the plasma membrane and ...
关键词：IQD21 KTN1 lobe outgrowth pavement cell interdigitation transfacial microtubules 
Planar cell polarity regulators in asymmetric organogenesis during development and disease
《Journal of Genetics and Genomics》2023年第2期63-76,共14页De-Li Shi 
supported by grants from the National Natural Science Foundation of China(grant number 32070813);the French Muscular Dystrophy Association (AFM-Telethon grant number 23545);the Centre National de la Recherche Scientifique;the Sorbonne University
The phenomenon of planar cell polarity is critically required for a myriad of morphogenetic processes in metazoan and is accurately controlled by several conserved modules.Six“core”proteins,including Friz zled,Flami...
关键词：Planar cell polarity Wnt/PCP signaling Left-right asymmetry Heart and gut morphogenesis Lung and kidney branching Inner ear hair cell orientation Limb outgrowth 
Age-induced changes in lung microenvironment: from melanoma dormancy to outgrowth
《Signal Transduction and Targeted Therapy》2023年第2期333-334,共2页Juan Jin Li Li Caiyun Fu 
This work was supported by the Zhejiang Provincial Natural and Science Foundation of China under Grant No.LD22H310004.
In a recent study published in Nature,Mitchell E.Fane et al.revealed the critical role of the aged microenvironment in the reactivation of melanoma cells from dormancy.1 The authors found that age-induced lung fibrobl...
关键词：MELANOMA LUNG MICROENVIRONMENT 
Additive-lathe 3D bioprinting of bilayered nerve conduits incorporated with supportive cells被引量：5
《Bioactive Materials》2021年第1期219-229,共11页Jingyi Liu Bin Zhang Liang Li Jun Yin Jianzhong Fu 
the National Key Research and Development Program of China(Grant No.2018YFA0703000);the Key Research and Development Program of Zhejiang Province(Grants No.2017C01063,No.2017C01054);the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(Grant No.51821093);the Fundamental Research Funds for the Central Universities(Grant Nos.2019XZZX003‐02 and 2019FZA4002).
Nerve conduits have been identified as one of the most promising treatments for peripheral nerve injuries,yet it remains unsolved how to develop ideal nerve conduits with both appropriate biological and mechanical pro...
关键词：Nerve conduit Mesenchymal stem cells Additive-lathe 3D bioprinting Gelatin methacrylate Neuron outgrowth 
Physical understanding of axonal growth patterns on grooved substrates:groove ridge crossing versus longitudinal alignment被引量：3
《Bio-Design and Manufacturing》2020年第4期348-360,共13页Deming Zhang Hairui Suo Jin Qian Jun Yin Jianzhong Fu Yong Huang 
This study was partially supported by the National Key Research and Development Program of China(Grant No.2018YFA0703000);the Key Research and Development Program of Zhejiang Province(Grant No.2017C01063);the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(Grant No.51821093);the National Natural Science Foundation of China(Grant Nos.U1609207,11672268);ZJU Scholarship for Outstanding Doctoral Candidates and Scholarship Program supported by China Scholarship Council(No.201906320187).
Surface topographies such as micrometric edges and grooves have been widely used to improve neuron outgrowth.However,finding the mechanism of neuron–surface interactions on grooved substrates remains a challenge.In t...
关键词：Grooved substrates Neuron outgrowth Axonal outgrowth model Axonal crossing 
Safflower Yellow Compounds Alleviate Okadaic Acid-Induced Impairment of Neurite Outgrowth in Differentiated SH-SY5Y Cells被引量：1
《Biomedical and Environmental Sciences》2020年第10期812-816,共5页WANG Zhen Hua SHI Xiao Bing LI Gang HAO Xue Yan YUAN Zhen Zhen CAO Xiao Hai WANG Hong Lun LI Ji MA Cheng Jun 
supported by the National Science Foundation of China[31870333];the Taishan Scholar Program of Shandong Province[tshw201502046];Shandong Provincial Science Foundation[ZR2019MH094];Yantai ShuangBai Scholar Program;Qinghai Province Applied Basic Research Project[2020-ZJ-905];the Open Project of State Key Laboratory of Plateau Ecology and Agriculture,Qinghai University[2018-KF-05]。
The dynamic assembly of microtubules plays a key role in maintaining structural and functional integrity of eukaryotic cel s,especial y with regard to neuronal differentiation or neurite outgrowth and synaptic plastic...
关键词：OUTGROWTH formation. INTEGRITY 
Role of miR-124 in the regulation of retinoic acid-induced Neuro-2A cell differentiation被引量：4
《Neural Regeneration Research》2020年第6期1133-1139,共7页Qun You Qiang Gong Yu-Qiao Han Rou Pi Yi-Jie Du Su-Zhen Dong 
supported by the Natural Science Foundation of Shanghai of China,No.16ZR1410500(to SZD)
Retinoic acid can cause many types of cells,including mouse neuroblastoma Neuro-2 A cells,to differentiate into neurons.However,it is still unknown whether microRNAs(miRNAs)play a role in this neuronal differentiation...
关键词：IMMUNOFLUORESCENCE MAP2 micro RNA mi R-124 Neuro-2A cells NEURITE OUTGROWTH neuronal differentiation OVEREXPRESSION real-time PCR RETINOIC acid 
Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage被引量：8
《Neural Regeneration Research》2020年第6期1071-1078,共8页Rais Reskiawan Abdulkadir Mansour Alwjwaj Othman Ahmad Othman Kamini Rakkar Ulvi Bayraktutan 
Part of this study has been supported by a grant to Dr Bayraktutan from The Dunhill Medical Trust(R459/0216)
Breakdown of blood-brain barrier,formed mainly by brain microvascular endothelial cells(BMECs),represents the major cause of mortality during early phases of ischemic strokes.Hence,discovery of novel agents that can e...
关键词：cell-based therapy ENDOTHELIAL progenitor CELLS ENDOTHELIUM ischemic stroke neurodegeneration novel therapeutics OUTGROWTH ENDOTHELIAL CELLS regenerative MEDICINE stem CELLS translational MEDICINE 
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