SYNOVIUM

作品数：30被引量：105H指数：6
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相关领域：医药卫生更多>>
相关作者：丛锐军秦树存蒋励更多>>
相关机构：复旦大学上海市第十人民医院北京大学第三医院泰山医学院更多>>
相关期刊：《Chinese Medical Journal》《Chinese Medical Sciences Journal》《Plastic and Aesthetic Research》《Journal of Traditional Chinese Medicine》更多>>
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Corrigendum to“Synergistically targeting synovium STING pathway for rheumatoid arthritis treatment”[Bioact Mater 24(2022)37–53]
《Bioactive Materials》2024年第10期665-666,共2页Haotian Shen Lulu Jin Qiangqiang Zheng Ziqiang Ye Linxiang Cheng Yuxu Wu Honghao Wu Tae yong Jon Wenduo Liu Zongyou Pan Zhengwei Mao Yue Wang 
The authors regret that two images in Fig.3A were originally misplaced by a careless mistake.The corrected versions of these images are provided below.These corrections do not alter any findings and conclusions report...
关键词：correction finding MISTAKE 
Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling
《Protein & Cell》2024年第6期441-459,共19页Feifei Liu Yi Lu Xuebao Wang Shuhui Sun Huize Pan Min Wang Zehua Wang Weiqi Zhang Shuai Ma Guoqiang Sun Qun Chu Si Wang Jing Qu Guang-Hui Liu 
supported by the National Natural Science Foundation of China(92149301,81921006,82125011);the National Key Research and Development Program of China(2022YFA1103700,2022YFA1103800,2020YFA0804000,2020YFA0112200,2021YFF1201000,the STI2030-Major Projects-2021ZD0202400);the National Natural Science Foundation of China(92168201,91949209,92049304,92049116,32121001,82192863,82122024,82071588,32000500,82271600);CAS Project for Young Scientists in Basic Research(YSBR-076,YSBR-012);the Project for Technology Development of Beijing-affiliated Medical Research Institutes(11000023T000002036310);Youth Innovation Promotion Association of CAS(E1CAZW0401,2023092,2022083);the Informatization Plan of Chinese Academy of Sciences(CAS-WX2021SF-0301,CAS-WX2022SDC-XK14,CAS-WX2021SF-0101);New Cornerstone Science Foundation through the XPLORER PRIZE(2021-1045);Excellent Young Talents Program of Capital Medical University(12300927);Excellent Young Talents Training Program for the Construction of Beijing Municipal University Teacher Team(BPHR202203105);Young Elite Scientists Sponsorship Program by CAST(2021QNRC001).
The synovium,a thin layer of tissue that is adjacent to the joints and secretes synovial fluid,undergoes changes in aging that contribute to intense shoulder pain and other joint diseases.However,the mechanism underly...
关键词：FOXO1 DEGENERATION inflammation 
Advanced nanoparticles in osteoarthritis treatment
《Biomaterials Translational》2024年第2期95-113,共19页Qiushi Liang Zhiliang Cheng Ling Qin 
supported by National Institutes of Health,Nos.R21AR078650,R01AG067698,R01AR079875(to LQ),R01AR080820;Health Research Formula Fund from the Pennsylvania Department of Health(to ZC).
Osteoarthritis(OA)is the most prevalent degenerative joint disorder,affecting hundreds of millions of people globally.Current clinical approaches are confined to providing only symptomatic relief.Research over the pas...
关键词：CARTILAGE LIPOSOME MICELLE NANOPARTICLES OSTEOARTHRITIS SYNOVIUM 
Effect of Small Needle Knife on Autophagy and TGF-β in Synovial Fluid of KOA Rats
《Chinese Journal of Biomedical Engineering(English Edition)》2024年第1期33-39,共7页ZHENG Kang-hua LIN Zeng-ping CHEN Yong 
School Management Project of Fujian University of Traditional Chinese Medicine,grant number:No.X2018013-Platform,XB2022023;Natural Science Foundation of Fujian Province,grant number:No.2018J01873,2021J01890
Objective:To explore the effects of small needle knife on the autophagy function of synovium and the expression of TGF-βin synovial fluid of KOA rats,so as to provide a new theoretical basis for the treatment of KOA....
关键词：small needle knife knee osteoarthritis(KOA) SYNOVIUM AUTOPHAGY transforming growth factorβ(TGF-β) 
Synergistically targeting synovium STING pathway for rheumatoid arthritis treatment被引量：7
《Bioactive Materials》2023年第6期37-53,共17页Haotian Shen Lulu Jin Qiangqiang Zheng Ziqiang Ye Linxiang Cheng Yuxu Wu Honghao Wu Tae Gyong Jon Wenduo Liu Zongyou Pan Zhengwei Mao Yue Wang 
supported by the National Natural Science Foundation of China(81772382,22161132027 and 82102599);the Key Research Program in Zhejiang Province,Science Technology Department of Zhejiang Province(2020C03042);the Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study(SN-ZJU-SIAS-006).
Rheumatoid arthritis(RA)is a common autoimmune disease leading to pain,disability,and even death.Although studies have revealed that aberrant activation of STING was implicated in various autoimmune diseases,the role ...
关键词：Mesoporous nanoparticles STING INFLAMMATION Drug delivery Rheumatoid arthritis 
Tetrahedral framework nucleic acids promote the biological functions and related mechanism of synovium-derived mesenchymal stem cells and show improved articular cartilage regeneration activity in situ被引量：5
《Bioactive Materials》2022年第3期411-427,共17页Liwei Fu Pinxue Li Junyao Zhu Zhiyao Liao Cangjian Gao Hao Li Zhen Yang Tianyuan Zhao Wei Chen Yu Peng Fuyang Cao Chao Ning Xiang Sui Quanyi Guo Yunfeng Lin Shuyun Liu 
This study was supported by the National Key R&D Program of China(2019YFA0110600).
Many recent studies have shown that joint-resident mesenchymal stem cells(MSCs)play a vital role in articular cartilage(AC)in situ regeneration.Specifically,synovium-derived MSCs(SMSCs),which have strong chondrogenic ...
关键词：Tetrahedral framework nucleic acids Articular cartilage regeneration Mesenchymal stem cells Chondrogenic differentiation 
Metabolomics study of biochemical changes in the serum and articular synovium tissue of moxibustion in rats with collagen-induced arthritis被引量：4
《World Journal of Acupuncture-Moxibustion》2021年第1期30-43,共14页Xiang-tian PANG Yong-yi ZHANG Yu-fei LENG Yao YAO Rui Zhang Dan-wen WANG Xiao XU Zhi-ling SUN 
National Natural Science Foundation of China:81774383,81904274;supported by"Nursing Advantageous Discipline Construction Project in Jiangsu Universities"of Nanjing University of Chinese medicine:2019YSHL008,2019YSHL021。
Objective:To demonstrate the rheumatoid arthritis(RA)mechanisms by determining the biochemical changes.To investigate the therapeutic mechanism of moxibustion in RA-model rats using a gas chromatography-mass spectrome...
关键词：Gas chromatography-mass spectrometry Metabolomics MOXIBUSTION Rheumatoid arthritis Collagen-induced arthritis 
Effect of moxibustion on PI3K/Akt/mTOR signaling pathway in foot-pad synovium in rats with rheumatoid arthritis
《China Medical Abstracts(Internal Medicine)》2021年第1期9-9,共1页HAO Feng 
Objective To observe the effect of moxibustion on phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin protein (PI3K/Akt/mTOR) signaling pathway in the foot-pad synovial tissue in rats with rhe...
关键词：PI3K/AKT/MTOR MOXIBUSTION RATS 
Diagnostic value of serum Interleukin-6 combined with synovial IL-6 and C-reactive protein for prosthesis joint infection in patients after joint arthroplasty
《Journal of Hainan Medical University》2021年第4期40-44,共5页Ze-Xiao Huang Bo Xing 
Natural science fund project of Hainan Province(No.819MS128)。
Objective:To explore the diagnostic value of serum Interleukin-6(IL-6)combined with synovial IL-6 and C-reactive protein for prosthesis joint infection(PJI)in patients after joint arthroplasty.Methods:A total of 253 p...
关键词：INTERLEUKIN-6 C-reactive protein SYNOVIUM Prosthesis joint infection Joint arthroplasty DIAGNOSIS 
Effect of Wenhua Juanbi Recipe(温化蠲痹方) on Expression of Receptor Activator of Nuclear Factor Kappa B Ligand,Osteoprotegerin,and Tumor Necrosis Factor Receptor Superfamily Member 14 in Rats with Collagen-Induced Arthritis被引量：2
《Chinese Journal of Integrative Medicine》2017年第3期208-214,共7页LIU Xi-de WANG Yun-qing CAI Long YE Li-hong WANG Fang FENG Ying-ying 
Supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY12H29008);the Zhejiang Provincial Project of Traditional Chinese Medicine Science and Technology Plan(No.2008CA086,2009CB195,2012ZB121,2015ZA143);the Hangzhou Health Science and Technology Plan(No.2010B027,No.2014A37);the Hangzhou Social Development Plan(No.20120633B12,No.20160533B45)
Objective： To study the effect of Wenhua Juanbi Recipe（温化蠲痹方, WJR） on expression of receptor activator of nuclear factor kappa B ligand（RANKL）, osteoprotegerin（OPG）, and tumor necrosis factor receptor supe...
关键词：Wenhua Juanbi Recipe collagen-induced arthritis receptor activator of nuclear factor kappa B ligand osteoprotegerin tumor necrosis factor receptor superfamily member 14 synovium peripheral blood Chinese medicine 
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