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作品数：66被引量：84H指数：5
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相关领域：医药卫生更多>>
相关作者：张勤刘贵秋张传山王坚马喆更多>>
相关机构：复旦大学附属肿瘤医院天津市第三中心医院桂林医学院附属医院上海长征医院更多>>
相关期刊：《Surgical Science》《中国实用医药》《Chinese Medical Journal》《World Journal of Integrated Traditional and Western Medicine》更多>>
相关基金：国家自然科学基金国家教育部博士点基金更多>>
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Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment
《International Journal of Oral Science》2025年第1期66-81,共16页Wenxiu Yuan Jiaqi Liu Zhenzhen Zhang Chengxinyue Ye Xueman Zhou Yating Yi Yange Wu Yijun Li Qinlanhui Zhang Xin Xiong Hengyi Xiao Jin Liu Jun Wang 
supported by National Natural Science Foundation of China(Nos.82271019,82472149,82471024);Sichuan Science and Technology Program(No.24ZDYF0099);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD-03-202101)to J.W.
The ambiguity of etiology makes temporomandibular joint osteoarthritis(TMJOA)“difficult-to-treat”.Emerging evidence underscores the therapeutic promise of exosomes in osteoarthritis management.Nonetheless,challenges...
关键词：OSTEOARTHRITIS ELEVATED LOADING 
Nature's lubrication solutions
《Friction》2025年第1期3-9,共7页Jacob Klein 
Support of this work by the European Research Council(advanced grant CartiLube 743016);the McCutchen Foundation,the Israel Science Foundation–National Natural Science Foundation of China Joint Research Program(No.3618/21);the Israel Science Foundation(No.1229/20)is gratefully acknowledged.
We briefly review the organizing principles that nature has selected to reduce friction between sliding tissues in the body to maintain their well-being.This is of especial relevance where large stresses are involved,...
关键词：biolubrication BIOTRIBOLOGY articular cartilage lubrication hydration lubrication boundary lubrication lipid boundary layers synovial lipids 
Arthroscopic synovectomy for synovial hyperplasia in chronic knee gouty arthritis:A case report
《World Journal of Orthopedics》2024年第11期1101-1108,共8页Ghuna A Utoyo Calvin Calvin 
BACKGROUND Chronic synovitis due to chronic knee gouty arthritis(KGA)resulting in synovial hyperplasia has not been documented in the current literature,and thus the optimal management for this condition remains uncle...
关键词：Chronic knee gouty arthritis Recurrent knee effusion Synovial hyperplasia Arthroscopic synovectomy Case report 
Small moleculeα-methylene-γ-butyrolactone,an evolutionarily conserved moiety in sesquiterpene lactones,ameliorates arthritic phenotype via interference DNA binding activity of NF-κB
《Acta Pharmaceutica Sinica B》2024年第8期3561-3575,共15页Kegang Linghu Wenqing Cui Taiqin Li Yueting Tuo Dasong Wang Huiqi Pan Tian Zhang Ligen Lin Hua Yu Xiaoxia Hu Haiyang Li Xiangchun Shen 
support by the National Natural Science Foundation of China(82260801);China Postdoctoral Science Foundation(2023M730815,China);Excellent Young Talents Plan of Guizhou Medical University(2023110,China);the Guizhou Provincial Scientific and Technologic Innovation Base([2023]003,China);the High Level Innovation Talents(GCC[2023]048,China);Science and Technology Development Fund,Macao SAR(0159/2020/A3,China);Guizhou Provincial Science and Technology Project(ZK[2024]152,China);Guizhou Provincial Health Commission Science and Technology Foundation(gzwkj2023-153,China)are gratefully acknowledged.
Rheumatoid arthritis(RA)is an inflammatory disease accompanied by abnormal synovial microenvironment(SM).Sesquiterpene lactones(SLs)are the main anti-inflammatory ingredients of many traditional herbs utilized in RA t...
关键词：a-Methylene-gbutyrolactone Rheumatoid arthritis NF-κB p65 Synovial microenvironment Sesquiterpene lactones 
Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis被引量：1
《Bioactive Materials》2024年第6期83-95,共13页Peng Hua Ruifeng Liang Suleixin Yang Yanbei Tu Meiwan Chen 
supported by the Science and Technology Development Fund,Macao SAR(File no.0124/2019/A3);the University of Macao(File no.MYRG2022-00203-ICMS,MYRG-GRG2023-00134-ICMS-UMDF).
Abnormal proliferation of aggressive fibroblast-like synoviocytes(FLS)and perpetuate synovial inflammation can inevitably accelerate the progression of rheumatoid arthritis(RA).Herein,a strategy of simultaneously prom...
关键词：Rheumatoid arthritis PUMA CELASTROL ANTI-INFLAMMATION Fibroblast-like synoviocyte apoptosis 
Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis被引量：2
《Bone Research》2024年第1期215-226,共12页Yuhang Liu Ruihan Hao Jia Lv Jie Yuan Xuelei Wang Churong Xu Ding Ma Zhouyi Duan Bingjun Zhang Liming Dai Yiyun Cheng Wei Lu Xiaoling Zhang 
This work was supported by grants from National Natural Science Foundation of China(81830078,82071868,32370892);Science and Technology Commission of Shanghai Municipality(23141901200);Health Commission of Shanghai Municipality(2022JC029);Biomaterials and Regenerative Medicine Institute Cooperative Research Project,Shanghai Jiaotong University School of Medicine(2022LHA11);Shanghai Key Laboratory of Orthopedic Implant(No.KFKT202206).
Osteoarthritis(OA)is a common degenerative disease worldwide and new therapeutics that target inflammation and the crosstalk between immunocytes and chondrocytes are being developed to prevent and treat OA.These attem...
关键词：OSTEOARTHRITIS METABOLISM inhibited 
Efficacy of electroacupuncture stimulating Zusanli(ST36)and Xuanzhong(GB39)on synovial angiogenesis in rats with adjuvant arthritis被引量：2
《Journal of Traditional Chinese Medicine》2023年第5期955-962,共8页JIANG Jianzhen ZHANG Xin LUO Zhenguo SU Chengguo ZHOU Haiyan JIANG Yuqing XIAO Xianjun CHEN Yunfei ZHU Jun 
Natural Science Foundation-funded Project:Study of Electroacupuncture on the Angiogenesis in Rheumatoid Arthritis Rats by HIF-1α/MDM2/p53 Signaling Pathway(No.81704152);Study on Immune Mechanisms of Macrophage M1/M2 Polarization in the Treatment of Rheumatoid Arthritis by Moxibustion“trengthening Body Resistance and Eliminating Evil”(No.81973959);Foundation of Science and Technology Department of Sichuan Province:Study of Electroacupuncture on the Punnus in Rheumatoid Arthritis Rats by HIF-1α,STAT3,Noth1 Signaling Pathway(No.2019YJ0491)。
OBJECTIVE:To investigate the efficacy of electroacupuncture(EA)stimulating Zusanli(ST36)and Xuanzhong(GB39)on synovial angiogenesis in rats with adjuvant arthritis(AA).METHODS:AA models were established by bilateral i...
关键词：ELECTROACUPUNCTURE ARTHRITIS experimental synovial angiogenesis receptor Notch1 signal transduction 
Tppp3~+synovial/tendon sheath progenitor cells contribute to heterotopic bone after trauma被引量：1
《Bone Research》2023年第3期548-559,共12页Ji-Hye Yea Mario Gomez-Salazar Sharon Onggo Zhao Li Neelima Thottappillil Masnsen Cherief Stefano Negri Xin Xing Qizhi Qin Robert Joel Tower Chen-Ming Fan Benjamin Levi Aaron W.James 
funded by the NIH/NIAMS (R01 AR070773,R01 AR068316,R01 DE031028,R21 AR078919);USAMRAA through the Peer Reviewed Medical Research Program (W81XWH-18-1-0121,W81XWH-18-1-0336);the Peer Reviewed Orthopaedic Research Program (W81XWH-20-10795);Broad Agency Announcement (W81XWH-1810613);the American Cancer Society (Research Scholar Grant,RSG-18-027-01-CSM);the Maryland Stem Cell Research Foundation;funded by the NIH (R01 AR079171,R01 AR078324,and R01 AR071379)。
Heterotopic ossification(HO)is a pathological process resulting in aberrant bone formation and often involves synovial lined tissues.During this process,mesenchymal progenitor cells undergo endochondral ossification.N...
关键词：PROGENITOR TENDON REPORTER 
复发性咽部原发滑膜肉瘤1例
《中国耳鼻咽喉头颈外科》2022年第11期740-741,共2页陶绮蕾 朱雅静 李力 吴建 
1 临床资料 患者,女,37岁,因“确诊口咽滑膜肉瘤5年,吞咽异物感4个月余”于2021-11-14日入院。患者5年前于海军军医大学第二附属医院耳鼻咽喉科在全麻下行“左侧扁桃体新生物切除术”,术后病理:梭形细胞滑膜肉瘤。后在我院肿瘤科行“吡...
关键词：肉瘤 滑膜(Sarcoma Synovial) 咽(Pharynx) 肿瘤复发 局部(Neoplasm Recurrence Local) 
Primary tuberculosis of the left greater trochanter of femur:a case report
《Clinical Research Communications》2022年第2期29-32,共4页Zhuang Liang Bo Dong Pu-Wei Yuan Feng Yang Xun Li De-Yu Liu Zhan-Kui Wang Wu-Lin Kang 
was funded by Key Research And Development Project of Science and Technology Department of Shaanxi Province(No.2021SF419);Key Research And Development Program of Social Development of Xianyang Science and Technology Bureau(No.2020K02-109);Discipline Construction Innovation Team of Shaanxi University of Traditional Chinese Medicine(No.2019YL-02);Shaanxi University of Traditional Chinese Medicine Graduate Student Innovation Project of Universal-level scientific Research Project(Study on the mechanism of acupotomy in the treatment of femoral head necrosis 2021CX12)。
Tuberculosis of the greater trochanter of the femur is caused by mycobacterium tuberculosis directly or indirectly invading the greater trochanter of the femur.The clinical manifestations are intermittent pain on the ...
关键词：femoral greater trochanter TUBERCULOUS synovial capsule bone type 
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