supported by the Priority Academic Program Development of Jiangsu Higher Education Institutes of China(PAPD);the Science and Technology Plan Project of Nantong of China,No.JC2020026(to JW);the National Science Research of Jiangsu Higher Education Institutions of China,No.19KJB310012(to RYY)。
The rapid formation of a glial/fibrotic scar is one of the main factors hampering axon growth after spinal cord injury. The bidirectional Eph B2/ephrin-B2 signaling of the fibroblast-astrocyte contact-dependent intera...
Peripheral nerve fibroblasts play an important role in the process of nerve development and regeneration.The present study revealed that fibroblasts with different tissue sources,such as peripheral nerve fibroblasts(N...
supported by the United States National Institute of Health grant 1K08DC012535(to MJB);Program for Neurology Research and Discovery;the Sinai Medical Staff Foundation Neuroscience Scholar Fund(to ELF)
The intricate anatomy and physiology of cranial nerves have inspired clinicians and scientists to study their roles in the nervous system. Damage to motor cranial nerves may result from a variety of organic or iatroge...
mainly supported by the Ministerio de Economíay Competitividad of Spain(#SAF 2014-59701)(to CC)
Peripheral nerve injuries caused by accidents may lead to paralysis,sensory disturbances,anaesthesia,and lack of autonomic functions.Functional recovery after disconnection of the motoneuronal soma from target tissue ...
supported in part by the National Natural Science Foundation of China,No.61361160415,81271684,81501570;the Major State Basic Research Development of China(973 Program),No.2011CB013304;the Medicine-Engineering Interdisciplinary Research Grant from Shanghai Jiao Tong University in China,No.YG2014ZD09;a grant from the Youth Eastern Scholar Program at Shanghai Institutions of Higher Learning in China,No.QD2015007
Essential tremor, also referred to as familial tremor, is an autosomal dominant genetic disease and the most common movement disorder. It typically involves a postural and motor tremor of the hands, head or other part...
supported by a grant from National Institute of Health(NIH);Grant No.NS040433
Amyotrophic lateral sclerosis is a motoneuron degenerative disease that is challenging to diagnose and presents with considerable variability in survival.Early identification and enhanced understanding of symptomatic ...
Spinal root avulsion is an excellent model for studying the re- sponse of motoneurons to severe injury to their axons (Koliat- sos et al., 1994). In this model (‘Avulsion Model'), spinal roots are torn off from ...
Nicotinic acetylcholine receptors (nAChRs) are expressed in brainstem and spinal cord regions involved in the control of breathing. These receptors mediate central cholinergic regulation of respiration and effects o...
Objective: To explore the mechanism of neurotropism in peripheral nerve regeneration by assessing the bioactivity of regeneration microcircumstance on motoneurons. Methods The motor branch Of femoral nerve to quadrice...
This study was supported by the grant from ClimbingProgram of Chinese Committee of Science
BZ]Dendro dendritic and dendro somatic projections are common between spinal motoneurons. We attempted to clarify whether there are functional connections through these projections. Methods. Motoneurons were antidromi...