We thank Dr.Xianzhu Xia(Academy of Military Medical Sciences)for providing the CVS-11 virus.We thank Dr.Zhenfang Fu(Huazhong Agricultural University)for providing the CVS-24 virus.This work was supported by the National Key Research and Development Program of China(2016YFD0500400);National Natural Science Foundation of China(31772742);Natural Science Foundation of Guangdong(2015A03031103).
Rabies is caused by infection of rabies virus(RABV)and remains a serious threat to the global public health.Except for the requirement for cold chain and high cost of human rabies immune globulin,no small molecule dru...
Award Number NIH-2R15AT008277-02(USA)from the National Center for Complementary and Integrative Health that provided funding to Pamela Weathers for some of the artemisinin bioavailability studies described and cited herein
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world.Despite considerable research,few therapies have proven effective and bee...
This project was supported by grants from the National Natural Science Foundation of China(81503094,81573410,and 81603071);the China Postdoctoral Science Foundation(2016M600524);and the Qingdao Postdoctoral Applied Research Project(2016072,Jian-jun Gao,Qingdao University).
Sorafenib is currently the standard chemotherapy drug for treatment of advanced hepatocellular carcinoma(HCC).But its efficacy requires improvement,it is imperative to seek therapeutic strategies that combine sorafeni...
Supported by the National Natural Science Foundation of China(No.81570104);Key Research and Development Project of Shandong Province(No.2015GSF118025,2015GSF118058,2016GSF201026)。
Although current therapeutic methods against hematological malignancies are effective in the early stage,they usually lose their effectiveness because of the development of drug resistances.Seeking new drugs with sign...
All the original references were provided by the Nobel Laureate Youyou Tu. The publication process involving the discovery of artemisinin was collected and sorted by her first Ph D student, Associate Professor Man-Yua...
Discovered by Youyou Tu, one of the 2015 Nobel Prize winners in Physiology or Medicine, together with many other Chinese scientists, artemisinin, artemether and artesunate, as well as other artemisinins, have brought ...
supported by a Swiss Pharma Nigeria PLC Grant given to AS,and by World Bank Malaria Booster Project and the Global Fund for Malaria to Federal Ministry of Health,Abuja,Nigeria through Drug Therapeutic Efficacy Testing in Nigeria.
Background:Artemisinin-based combination therapies are recommended as first-line treatments for uncomplicated falciparum malaria,but there is little evaluation of their efficacy and effects on uncomplicated malaria-as...
supported by grants to Zeng Qing Ping from National Natural Science Foundation of China(81273620)
Calorie restriction(CR) promotes longevity among distinct organisms from yeast to mammals. Although CR-prolonged lifespan is believed to associate with enhanced respiratory activity, it is apparently controversial for...