MICROARRAY

作品数:440被引量:1533H指数:15
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相关领域:医药卫生生物学更多>>
相关作者:范保星吴德昌张开泰石磊黄圆更多>>
相关机构:清华大学复旦大学军事医学科学院北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>
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  • 期刊=World Journal of Gastroenterologyx
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Dysregulation of microRNA in cholangiocarcinoma identified through a meta-analysis of microRNA profiling
《World Journal of Gastroenterology》2020年第29期4356-4371,共16页Somsak Likhitrattanapisal Supeecha Kumkate Pravech Ajawatanawong Kanokpan Wongprasert Rutaiwan Tohtong Tavan Janvilisri 
Supported by the Thailand Research Fund,No.DBG5980006;UK-Thailand Research Collaborations(Newton Fund),No.MR/N01247X/1.
BACKGROUND In the past decades,the potential of microRNA(miRNA)in cancer diagnostics and prognostics has gained a lot of interests.In this study,a meta-analysis was conducted upon the pooled miRNA microarray data of c...
关键词:CHOLANGIOCARCINOMA MICROARRAY MICRORNA META-ANALYSIS 
lncRNACNN3-206 activates intestinal epithelial cell apoptosis and invasion by sponging miR-212, an implication for Crohn’s disease被引量:6
《World Journal of Gastroenterology》2020年第5期478-498,共21页Na Li Rui-Hua Shi 
Supported by Postgraduate Research and Practice Innovation Program of Jiangsu Province,No.KYCX18_0174
BACKGROUND Statistics indicate that the incidence of Crohn’s disease(CD)is rising in many countries.The poor understanding on the pathological mechanism has limited the development of effective therapy against this d...
关键词:Crohn’s disease MICROARRAY lncRNACNN3-206 Gene regulation Cell migration and invasion miR-212 
Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine被引量:1
《World Journal of Gastroenterology》2017年第41期7369-7386,共18页Finbarr O’Sullivan Joanne Keenan Sinead Aherne Fiona O’Neill Colin Clarke Michael Henry Paula Meleady Laura Breen Niall Barron Martin Clynes Karina Horgan Padraig Doolan Richard Murphy 
Supported by A Strategic Alliance Programme between Alltech Ltd. and DCU and also Enterprise Ireland Innovation Partnership Grant(IP 2015 0375)
AIM To identify mi RNA-regulated proteins differentially expressed between Caco2 and HT-29: two principal cell line models of the intestine.METHODS Exponentially growing Caco-2 and HT-29 cells were harvested and prepa...
关键词:CACO-2 HT-29 MICROARRAY PROTEOMICS miRNA Targetscan Gene ontology 
hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma被引量:3
《World Journal of Gastroenterology》2017年第9期1568-1575,共8页Sumadi Lukman Anwar Till Krech Britta Hasemeier Elisa Schipper Nora Schweitzer Arndt Vogel Hans Kreipe Reena Buurman Britta Skawran Ulrich Lehmann 
Supported by the Deutsche Forschungsgemeinschaft,No.(DFG) SFB-TRR77 “Liver cancer”(Project B1)
To screen clinically relevant microRNAs (miRNAs) silenced by DNA methylation in human hepatocellular carcinoma (HCC).METHODSKnockdown of DNA methyltransferases (DNMTs) using siRNAs and miRNA profiling in HCC cell line...
关键词:hsa-miR-183 DNA methylation DNMT knockdown microRNA microarray 
Dysregulation of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901
《World Journal of Gastroenterology》2017年第7期1189-1202,共14页Xiao-Que Xie Qi-Hong Zhao Hua Wang Kang-Sheng Gu 
Supported by Projects of Foreign Science and Technology Cooperation of Anhui Province of Anhui Province,No.1604b0602027;New Century Excellent Talents in University,Ministry of Education of China,No.NCET-13-0644;Wanjiang Scholars Program of Anhui Province of China
AIM To explore novel therapeutic target of cisplatin resistance in human gastric cancer.METHODS The sensitivity of SGC7901 cells and cisplatin-resistant SGC7901 cells(SGC7901/DDP) for cisplatin were detected by 3-(4,5...
关键词:Gastric cancer Dysregulate Cisplatin resistance MICROARRAY BIOLOGY 
Plasma long noncoding RNA expression profile identified by microarray in patients with Crohn's disease被引量:5
《World Journal of Gastroenterology》2016年第19期4716-4731,共16页Dong Chen Jiang Liu Hui-Ying Zhao Yi-Peng Chen Zun Xiang Xi Jin 
Supported by National Natural Science Foundation of China,No.81370008 and No.81000169;Natural Science Foundation of Zhejiang Province,No.R2110159,No.LY15H030006 and No.LY16H030003;Science Technology Project of Zhejiang Province,No.2014C33205
AIM: To investigate the expression pattern of plasma long noncoding RNAs (lncRNAs) in Chrohn’s disease (CD) patients.METHODS: Microarray screening and qRT-PCR verification of lncRNAs and mRNAs were performed i...
关键词:Crohn’ s disease Long noncoding RNA Inflammatory bowel disease PLASMA MICROARRAY 
Changes in gene expression in liver tissue from patients with fulminant hepatitis E被引量:2
《World Journal of Gastroenterology》2015年第26期8032-8042,共11页Anshu Naik Amit Goel Vinita Agrawal Aditya N Sarangi Nanda Chhavi Vineeta Singh Shahid Jameel Rakesh Aggarwal 
Supported by National Institutes of Health,Bethesda,United States,No.5R01AI076192
AIM: To study host gene expression and numberof immune cells in liver tissues from patients with fulminant hepatitis E(FH-E).METHODS: Microarray-based expression profiling was done using Illumina Human WG-6_v3_Bead Ch...
关键词:CYTOTOXIC T CELLS Gene expression HepatitisE Hepatitis E virus Immune response Liver BIOPSY MICROARRAY Natural KILLER CELLS Pathogenesis 
Expression of pyruvate dehydrogenase is an independent prognostic marker in gastric cancer被引量:4
《World Journal of Gastroenterology》2015年第17期5336-5344,共9页Xu-Ren Sun Zhe Sun Zhi Zhu Hai-Xia Guan Chen-Yan Li Jun-Yan Zhang Yi-Ning Zhang Huan Zhou Hui-Jing Zhang Hui-Mian Xu Ming-Jun Sun 
Grants from the research projects in Liaoning Province Science and Technology Department,No.2007225017,No.2009225011-2 and No.2011415052;Science and Technology projects in Shenyang City,No.F11-264-1-19
AIM:To investigate the expression and prognostic role of pyruvate dehydrogenase(PDH) in gastric cancer(GC).METHODS:This study included 265 patients(194 male,71 female,mean age 59 years(range,29-81 years) with GC who u...
关键词:PYRUVATE DEHYDROGENASE GASTRIC CARCINOMA Tissue MICROARRAY Prognosis Immunohistochemicalanalysis 
Expression profile of microRNAs in gastrointestinal stromal tumors revealed by high throughput quantitative RT-PCR microarray被引量:3
《World Journal of Gastroenterology》2015年第19期5843-5855,共13页Han-Xing Tong Yu-Hong Zhou Ying-Yong Hou Yong Zhang Yuan Huang Bin Xie Jiong-Yuan Wang Quan Jiang Jun-Yi He Ye-Bo Shao Wu-Mei Han Ruo-Ying Tan Jun Zhu Wei-Qi Lu 
Supported by Grants from the Ministry of Health of the China,No.W2012RQ02;Shanghai Science and Technology Committee,No.12nm0501402;Shanghai Education Committee,No.120311
AIM: To investigate the microRNA(miRNA) expression profile in gastrointestinal stromal tumor(GIST) tissues that could serve as a novel diagnostic biomarker for GIST detection.METHODS: We performed a quantitative real-...
关键词:GASTROINTESTINAL STROMAL tumors MICRORNAS MICROARRAY analysis Real-time POLYMERASE chainreaction Diagnosis 
miR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis被引量:16
《World Journal of Gastroenterology》2014年第46期17439-17447,共9页Juan Xie Zhi-Hui Tan Xia Tang Ming-Shu Mo Yan-Ping Liu Run-Liang Gan Yi Li Li Zhang Guo-Qing Li 
Supported by National Natural Science Foundation of China,No.81071965
AIM: To profile expression of microRNAs (miRNAs) in gastric cancer cells and investigate the effect of miR-374b-5p on gastric cancer cell invasion and metastasis.
关键词:Gastric cancer microRNAs microarray miR-374b-5p RECK Invasion and metastasis 
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