Α-GLUCOSIDASE

作品数:97被引量:175H指数:6
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相关领域:医药卫生更多>>
相关作者:陈光英郑彩娟罗由萍周通肖音更多>>
相关机构:哈尔滨工业大学中国科学院大叶大学海南师范大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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Antidiabetic and antioxidant properties of Fagara zanthoxyloides root-bark ethyl acetate fraction:in-vitro enzyme inhibition and GC-MS analysis
《Life Research》2025年第1期32-43,共12页Christian Amah Parker Joshua Ikechukwu Okoro Favour Iyidiegwu Chibuike Brendan Linus Nsude Ugochukwu Nweke 
The application of therapeutic herbs in treatment of common infections and diseases has gained popularity in developing nations due to its cost-effectiveness and purported lower side effects compared to synthetic drug...
关键词:Fagara zanthoxyloides α-amylase andα-glucosidase ANTI-OXIDANT GC-MS 
Neuroprotective and antidiabetic lanostane-type triterpenoids from the fruiting bodies of Ganoderma theaecolum
《Chinese Journal of Natural Medicines》2025年第2期245-256,共12页Jiaocen Guo Li Yang Luting Dai Qingyun Ma Jiaoyang Yan Qingyi Xie Yougen Wu Haofu Dai Youxing Zhao 
supported by the National Natural Science Foundation of China (No.81973568);the Earmarked Fund for China Agriculture Research System (No.CARS-21);the Special Financial Project of the Ministry of Agriculture and Rural Areas (No.NFZX2024)。
Eight previously undescribed lanostane triterpenoids,including five nortriterpenoids with 26carbons,ganothenoids A-E(1-5),and three lanostanoids,ganothenoids F-H(6-8),along with 24 known ones(9-32),were isolated from ...
关键词:Ganoderma theaecolum Lanostane nortriterpenoids Neuroprotective effects PTP1B Α-GLUCOSIDASE 
Study on chemical constituents and biological activities of Sanghuangporus vaninii under static magnetic field
《分子科学学报》2024年第4期353-357,共5页LIU Xuwen ZHOU Jie YE Dongyan LI Qianhui YIN Shuren ZHANG Suyi BAI Helong 
supported by the Natural Science Foundation of Jilin Province(20220402050 GH,JJKH20220826KJ);Natural Science Foundation of Changchun Normal University(2020004).
The chemical composition and biological activity of Sanghuangporus vaninii solid culture treated by static magnetic field were studied.The compounds were isolated and purified using ultrasonic extraction and semi-prep...
关键词:Sanghuangporus vaninii chemical component static magnetic field Α-AMYLASE Α-GLUCOSIDASE pancreatic lipase 
Surface engineering of carbon dots for highly sensitive α-glucosidase assay and inhibition evaluation被引量:1
《Chinese Chemical Letters》2024年第3期193-197,共5页Meijuan Liang Gege Song Yeqing Wan Yingying Chen Fuan Wang Xiaoqing Liu 
supported by National Natural Science Foundation of China(Nos.32202171,22274121 and 22274123)。
Monitoringα-glucosidase(α-Glu)activity is of great significance for the early diagnosis of typeⅡdiabetes.Here the blue fluorescent carbon dots(CDs)were integrated with two different recognizing molecules,β-cyclode...
关键词:Α-GLUCOSIDASE Carbon dots Fluorescent sensor INHIBITOR Β-CYCLODEXTRIN 
Bioassay-guided isolation of α-Glucosidase inhibitory constituents from Hypericum sampsonii
《Chinese Journal of Natural Medicines》2023年第6期443-453,共11页TAO Linlan XU Shuangyu ZHANG Zizhen LI Yanan YANG Jue GU Wei YI Ping HAO Xiaojiang YUAN Chunmao 
supported by the National Natural Science Foundation of China(No.32270413,U1812403);the Science and Technology Department of Guizhou Province(No.QKH 2020-1Z076);the 13th batch of Outstanding Young Scientific and Technological Talents in Guizhou Province(No.QKHPTRC[2021]5633);Cultivation project of National Natural Science Foundation of Guizhou Medical University(No.19NSP003);the Education Department of Guizhou Province(No.QJH KY[2021]189);the Natural Science Foundation of Guizhou Province(No.QKHZYD[2022]4015);High-level Innovative Talents in Guizhou Province(Thousand Levels of Talent for Chunmao Yuan in 2018);“Light of the West”Talent Cultivation Program of Chinese Academy of Sciences for Chunmao Yuan(No.RZ[2020]82).
This study employed the α-glucosidase inhibitory activity model as an anti-diabetic assay and implemented a bioactivity-guided isolation strategy to identify novel natural compounds with potential therapeutic propert...
关键词:Hypericum sampsonii Chemical constituents Structure elucidation Α-GLUCOSIDASE Molecular docking 
Ethanol extract of Annona muricata Linn fruit perform antidiabetic effect on type 2 diabetic mice through α-glucosidase inhibition
《Journal of Hainan Medical University》2023年第7期1-7,共7页QIN Hai-long YAO Jia-hui WANG Yan XU Qi-peng LIU Zheng LI You-bin GONG Jing-wen 
supported by 2020 College Students Innovation and Entrepreneurship Training Program(X202011810069);the National Natural Science Foundation of China(81460591)。
Objective:To explore the anti-diabetic effects and its underlying mechanism of Annona muricata Linn fruit ethanol extract(AME).Methods:Streptozotocin-induced type 2 diabetic(T2DM)mouse model was constructed.Those diab...
关键词:Annona muricata Linn Type 2 diabetes mellitus Α-GLUCOSIDASE Postprandial blood glucose 
Chemical constituents from aerial parts of Scoparia dulcis
《Chinese Herbal Medicines》2023年第1期151-154,共4页Yingbo Yang Zhuzhen Han Tong Tian Qi Liao Jiaran Geng Ying Xiao 
financial supports from the National Natural Science Foundation of China (32170402, 81703682, 81874335)。
Objective: To study the chemical constituents from the aerial parts of Scoparia dulcis.Methods: Various chromatographic techniques were used to separate the constituents and their structures were elucidated using spec...
关键词:ALKALOIDS chemical constituents α-glucosidase inhibitory activity Scoparia dulcis L. 
Antioxidant,antimicrobial,and α-glucosidase inhibitory activities of saponin extracts from walnut(Juglans regia L.) leaves被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2023年第2期60-69,共10页Youssef Elouafy Adil El Yadini Salma Mortada Mohamed Hnini Hicham Harhar Asaad Khalid Ashraf NAbdalla Abdelhakim Bouyahya Khang Wen Goh Long Chiau Ming My El Abbes Faouzi Mohamed Tabyaoui 
supported by the Deanship of Scientific Research at Umm Al-Qura University(Grant code:22UQU4331128DSR77).
Objective:To investigate the relationship between triterpenoid saponin content and antioxidant,antimicrobial,and α-glucosidase inhibitory activities of 70%ethanolic,butanolic,aqueous,supernate and precipitate extract...
关键词:Juglans regia leaves Triterpenoid saponin Antioxidant activity DPPH ABTS Antidiabetic activity Α-GLUCOSIDASE Antimicrobial activity 
Structural characterizations andα-glucosidase inhibitory activities of four Lepidium meyenii polysaccharides with different molecular weights
《Natural Products and Bioprospecting》2023年第1期568-576,共9页Luan Wen Zhou-Wei Wu Li-Wu Lin Abdulbaset Al-Romaima Xing-Rong Peng Ming-Hua Qiu 
the National Natural Science Foundation of China(No.31872675);the Cooperation Project with DR PLANT Company(2023).
Four polysaccharides(MCPa,MCPb,MCPc,MCPd)were obtained from Lepidium meyenii Walp.Their structures were characterized by chemical and instrumental methods including total sugar,uronic acid and protein content determi-...
关键词:Lepidium meyenii POLYSACCHARIDE Molecular weight Structural characterization α-Glucosidase inhibition 
New flavanone-monoterpene hybrids as α-glucosidase inhibitors from the root bark of Morus alba
《TMR Modern Herbal Medicine》2022年第4期37-41,共5页Lin-Lin Tian Hua Zhang 
Financial support is from the Natural Science Foundation of Shandong Province for Distinguished Young Scholars(No.JQ201721).
Objective The Morus alba root bark is a well-known Chinese herbal medicine called Sang-Bai-Pi and has often been used to relieve the hyperglycemic symptom of diabetes patients.The current work aims to further explore ...
关键词:Morus alba Flavanone Regio-isomerization ENANTIOMERIZATION α-Glucosidase inhibition 
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