Α-GLUCOSIDASE

作品数:97被引量:175H指数:6
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相关领域:医药卫生更多>>
相关作者:陈光英郑彩娟罗由萍周通肖音更多>>
相关机构:哈尔滨工业大学中国科学院大叶大学海南师范大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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  • 学科=医药卫生—中医学x
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Antidiabetic and antioxidant properties of Fagara zanthoxyloides root-bark ethyl acetate fraction:in-vitro enzyme inhibition and GC-MS analysis
《Life Research》2025年第1期32-43,共12页Christian Amah Parker Joshua Ikechukwu Okoro Favour Iyidiegwu Chibuike Brendan Linus Nsude Ugochukwu Nweke 
The application of therapeutic herbs in treatment of common infections and diseases has gained popularity in developing nations due to its cost-effectiveness and purported lower side effects compared to synthetic drug...
关键词:Fagara zanthoxyloides α-amylase andα-glucosidase ANTI-OXIDANT GC-MS 
Study on chemical constituents and biological activities of Sanghuangporus vaninii under static magnetic field
《分子科学学报》2024年第4期353-357,共5页LIU Xuwen ZHOU Jie YE Dongyan LI Qianhui YIN Shuren ZHANG Suyi BAI Helong 
supported by the Natural Science Foundation of Jilin Province(20220402050 GH,JJKH20220826KJ);Natural Science Foundation of Changchun Normal University(2020004).
The chemical composition and biological activity of Sanghuangporus vaninii solid culture treated by static magnetic field were studied.The compounds were isolated and purified using ultrasonic extraction and semi-prep...
关键词:Sanghuangporus vaninii chemical component static magnetic field Α-AMYLASE Α-GLUCOSIDASE pancreatic lipase 
Bioassay-guided isolation of α-Glucosidase inhibitory constituents from Hypericum sampsonii
《Chinese Journal of Natural Medicines》2023年第6期443-453,共11页TAO Linlan XU Shuangyu ZHANG Zizhen LI Yanan YANG Jue GU Wei YI Ping HAO Xiaojiang YUAN Chunmao 
supported by the National Natural Science Foundation of China(No.32270413,U1812403);the Science and Technology Department of Guizhou Province(No.QKH 2020-1Z076);the 13th batch of Outstanding Young Scientific and Technological Talents in Guizhou Province(No.QKHPTRC[2021]5633);Cultivation project of National Natural Science Foundation of Guizhou Medical University(No.19NSP003);the Education Department of Guizhou Province(No.QJH KY[2021]189);the Natural Science Foundation of Guizhou Province(No.QKHZYD[2022]4015);High-level Innovative Talents in Guizhou Province(Thousand Levels of Talent for Chunmao Yuan in 2018);“Light of the West”Talent Cultivation Program of Chinese Academy of Sciences for Chunmao Yuan(No.RZ[2020]82).
This study employed the α-glucosidase inhibitory activity model as an anti-diabetic assay and implemented a bioactivity-guided isolation strategy to identify novel natural compounds with potential therapeutic propert...
关键词:Hypericum sampsonii Chemical constituents Structure elucidation Α-GLUCOSIDASE Molecular docking 
Chemical constituents from aerial parts of Scoparia dulcis
《Chinese Herbal Medicines》2023年第1期151-154,共4页Yingbo Yang Zhuzhen Han Tong Tian Qi Liao Jiaran Geng Ying Xiao 
financial supports from the National Natural Science Foundation of China (32170402, 81703682, 81874335)。
Objective: To study the chemical constituents from the aerial parts of Scoparia dulcis.Methods: Various chromatographic techniques were used to separate the constituents and their structures were elucidated using spec...
关键词:ALKALOIDS chemical constituents α-glucosidase inhibitory activity Scoparia dulcis L. 
Antioxidant,antimicrobial,and α-glucosidase inhibitory activities of saponin extracts from walnut(Juglans regia L.) leaves被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2023年第2期60-69,共10页Youssef Elouafy Adil El Yadini Salma Mortada Mohamed Hnini Hicham Harhar Asaad Khalid Ashraf NAbdalla Abdelhakim Bouyahya Khang Wen Goh Long Chiau Ming My El Abbes Faouzi Mohamed Tabyaoui 
supported by the Deanship of Scientific Research at Umm Al-Qura University(Grant code:22UQU4331128DSR77).
Objective:To investigate the relationship between triterpenoid saponin content and antioxidant,antimicrobial,and α-glucosidase inhibitory activities of 70%ethanolic,butanolic,aqueous,supernate and precipitate extract...
关键词:Juglans regia leaves Triterpenoid saponin Antioxidant activity DPPH ABTS Antidiabetic activity Α-GLUCOSIDASE Antimicrobial activity 
New flavanone-monoterpene hybrids as α-glucosidase inhibitors from the root bark of Morus alba
《TMR Modern Herbal Medicine》2022年第4期37-41,共5页Lin-Lin Tian Hua Zhang 
Financial support is from the Natural Science Foundation of Shandong Province for Distinguished Young Scholars(No.JQ201721).
Objective The Morus alba root bark is a well-known Chinese herbal medicine called Sang-Bai-Pi and has often been used to relieve the hyperglycemic symptom of diabetes patients.The current work aims to further explore ...
关键词:Morus alba Flavanone Regio-isomerization ENANTIOMERIZATION α-Glucosidase inhibition 
Rapid identification of stigmastane-type steroid saponins from Vernonia amygdalina leaf based onα-glucosidase inhibiting activity and molecular networking
《Chinese Journal of Natural Medicines》2022年第11期846-853,共8页GAO Juanjuan ZHAO Mengling SHAN Shujun LI Yongyi LUO Jun LI Yi 
supported by the National Natural Science Foundation of China(No.81573550)。
Steroid saponins are secondary metabolites with multiple medicinal values that are found in large quantities in natural medicines,especially Vernonia amygdalina,a famous nature medicine for the treatment of tonsilliti...
关键词:Δ^(7 9(11))Stigmastane-type steroid saponins α-Glucosidase inhibitory activity Fragmentation pathways Diagnostic ions Molecular networking 
Termitomenins F and G,Two New Lignan Glucosides from Terminalia chebula var.tomentella(Kurz)C.B.Clarke被引量:1
《Natural Products and Bioprospecting》2021年第5期565-572,共8页Jun Yin Hong‑Tao Zhu Man Zhang Dong Wang Chong‑Ren Yang Ying‑Jun Zhang 
The extensive chemical investigation on the branches and leaves of Terminalia chebula var.tomentella(Combretaceae)led to the isolation of two new lignan glucosides with a furofuran skeleton,termitomenins F(1)and G(2)....
关键词:Terminalia chebula var.tomentella Lignan glucosides Hydrolyzable tannins α-Glucosidase inhibitory activity Calculated ECD 
Screening and functional evaluation of the glucose-lowering active compounds of total saponins of Baibiandou(Lablab Semen Album)被引量:3
《Digital Chinese Medicine》2021年第3期229-240,共12页HAN Jun ZHENG Qinfang FANG Liangzi HUANG Xiaolong 
funding support from the Program of the Educational Commission of Hunan Province of China(No.20B418)。
Objective To screen forα-glucosidase inhibitor active compounds in the total saponins of Baibiandou(Lablab Semen Album)based on UHPLC-Q-Exactive Orbitrap MS technology and to evaluate its hypoglycemic activity in viv...
关键词:Baibiandou(Lablab Semen Album) Total saponins UHPLC-Q-Exactive Orbitrap MS Α-GLUCOSIDASE Molecular docking Type 2 diabetic mice Chikusetsusaponin IVa 
Inhibitive efficacy of Nymphoides indica rhizome extract onα-glucosidase, and cross-link formation of advanced glycation end products
《Journal of Traditional Chinese Medicine》2021年第3期376-380,共5页Muhammad Hanif Muzammil Ahmad Khan Muhammad Ramzan Abdul Rafey Ali Zaman Imran Aziz Ama'null'ah Adnan Amin 
OBJECTIVE: To investigate the inhibitive efficacy of Nymphoides Indica(L.) Kuntze rhizome extract onα-glucosidase and on cross-link formation of advanced glycation end products(AGEs).METHODS: The plant extracts were ...
关键词:Nymphoides Indica alpha-glucosidases glycation end products advanced protein cross links antiglycation 
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