NUCLEOBASE

作品数：20被引量：38H指数：3
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相关作者：王一涛李绍平王静张礼和余沛霖更多>>
相关机构：澳门大学北京大学首都师范大学更多>>
相关期刊：《Regenerative Biomaterials》《Chemical Research in Chinese Universities》《Journal of Energy Chemistry》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划重庆市自然科学基金更多>>
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Functional nucleic acids with synthetic sugar or nucleobase moieties被引量：1
《Advanced Agrochem》2023年第3期236-245,共10页Ze Zhang Siqi Chen Zhe Li Hanyang Yu 
the National Key Research and Development Program of China(2019YFA0904000 and 2021YFF1200203);the National Natural Science Foundation of China(21977046 and 22277049);the Fundamental Research Funds for the Central Universities(0213–14380192);the Program for Innovative Talents and Entrepreneur in Jiangsu is gratefully acknowledged.
Functional nucleic acids including aptamers and DNAzymes are a class of valuable molecular tool for biotechnology.However,DNA and RNA aptamers and catalysts suffer from low biological stability and limited chemical di...
关键词：properties. SUGAR BASE 
Constructing Artificial Nucleobase Compilation to Enable Precise Molecular Medicine
《Chinese Journal of Chemistry》2023年第11期1385-1398,共14页Jingqi Chen Bo Liu Xuan Wang Xueliang Liu Dandan Yang Yu Yang 
supported by grants from the National Natural Science Foundation of China(Nos.22277072 and 22107065);"Clinic Plus"Outstanding Project(Nos.2021ZYB009 and 2021ZYB003)from Shanghai Key Laboratory for Nucleic Acid Chemistry Nanomedicine;Innovative research team of high-level local universities in Shanghai.
Nucleic acids are the hereditary information storage medium of life. Due to its high programmability and good biocompatibility, the applications of nucleic acids are not limited to their natural function. However, the...
关键词：NUCLEOBASES OLIGONUCLEOTIDES Biological activity APTAMER Drug delivery 
Supramolecular Nanofibers/Hydrogels of the Conjugates of Nucleobase,Saccharide,and Amino Acids
《Chinese Journal of Chemistry》2014年第4期313-318,共6页Dongdong Wu Xuewen Du Junfeng Shi Jie Zhou Bing Xu 
This work was supported by National Institutes of Health(No.NIH R01CA142746).
Three new hydrogelators based on the conjugates of three naturally occurring biological building blocks:nu-cleobase,saccharide,and amino acids,were explored.Being synthesized via a facile solid phase peptide synthesis...
关键词：HYDROGELATOR NUCLEOSIDE peptide nanofiber 
Analysis of the bioactive components from different growth stages of Fritillaria taipaiensis P. Y. Li被引量：12
《Acta Pharmaceutica Sinica B》2013年第3期167-173,共7页Rui Peng Peng Ma Rangyu Mo Nianxi Sun 
support from the Natural Science Foundation of Chongqing Municipality,China(CSTC,2011BA 5034);funded by the Chongqing Municipal Health Bureau,China(No.2009-1-12).
High-performance liquid chromatography(HPLC)coupled with an evaporative light scattering detector(ELSD)or a diode array detector(DAD)were utilized for the quantitative analysis of 4 alkaloids(peimisine,sipeimine,peimi...
关键词：Fritillaria taipaiensis P.Y.Li HPLC ELSD DAD Alkaloid NUCLEOSIDE NUCLEOBASE Quality control 
Preparation of Platinum(II) Complexes with 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide and its Deoxy-analogue被引量：7
《Chinese Chemical Letters》2001年第6期559-562,共4页Wen PEI Kobe JOZE 
The platinum (II) complexes of the [Pt (N4,N7-Ribavirin) (DMSO) Cl], [Pt (N4,N7-De-oxyribavirin) (DMSO) Cl] were obtained by the reactions of cis-[Pt (DMSO)2 Cl2] and K[Pt (DMSO) Cl3] with 1-??-D-ribofuranosyl-1,2,4-t...
关键词：Platinum(II) complexes ribavirin and deoxyribavirin nucleobase platination complexation reaction antitumor agents 
Synthesis of Conformationally LockedIsonucleosides: 2'-Deoxy-2'-nucleobase-5'-deoxy-1', 4' : 3' , 6'-dianhydro-D-mannitol
《Chemical Research in Chinese Universities》2001年第2期178-185,共9页TIAN Xiao-bing, ZHANG Ling, MIN Ji-mei and ZHANG Li-he (School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083, P. R. China) LU Yang, JIANG Reng-wang and ZHENG Qi-tai (Institute of Materia Medica, Peking Union Medical College &. Ch 
the National Natural Science Foundation of China.
Novel bicyclic isonucleosides, 2′-deoxy-2′ -nucleobase-5′-deoxy-1′ , 4′ : 3′ , 6′ -dianhydro- D-mannitol 10a-10c, were synthesized from D-glucose. The computer-assisted molecular simu- lation indicated that the...
关键词：Bicyclic isonucleoside Locked conformation SYNTHESIS 
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