supported by grants from the National Natural Science Foundation of China(82090033,82288101,U20A6005,32200801,and 32200967);China Postdoctoral Science Foundation(2021M700851,2023T160117,and 2023M740708).
The nucleus accumbens(NAc)plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness.However,the neural mechanisms underlying the relationship between arousal and emoti...
supported by the Corbett Estate Fund(62285-531021-41800,to EW);the Helen Vosburg McCrillus Plummer and Robert Edward Lee Plummer,Jr.Chair Fund(to JHH).
Neuron-astrocyte interactions are vital for the brain’s connectome.Understanding astrocyte activities is crucial for comprehending the complex neural network,particularly the population-level functions of neurons in ...
We thank research center“Symbiosis”and immunochemistry laboratory IBPPM RAS for their support with immunofuorescence analysis and confocal microscopy within Project No.GR 121031100266-3;SGO,FI,SA,BI,TA,DA,ZM,ED,AV,EA,VV,TA,KV,MM,and MA were supported by grant(No.23-75-30001);the Russian Science Foundation,DA and ED were supported by Grant(No.21-75-10088);the Russian Science Foundation and by Grant from the Russian Ministry of Science and High Education(No.075-15-2022-1094).
With the increase in the aging population,the global number of people with Alzheimer’s disease(AD)progressively increased worldwide.The situation is aggravated by the fact that there is no the efective pharmacologica...
supported by the University of Michigan startup funds and the NIH Grants R01 AT011652 and R01 HL156989.
The parabrachial nucleus(PBN)integrates interoceptive and exteroceptive information to control various behavioral and physiological processes including breathing,emotion,and sleep/wake regulation through the neural ci...
Sleep is a critical part of our daily routine.It impacts every organ and system of our body,from the brain to the heart and from cellular metabolism to immune function.A consistent daily schedule of quality of sleep m...
supported by the Scientific and Technological Innovation 2030 Program of China(2021ZD0203003)。
High-fat diet(HFD)-induced obesity is a growing epidemic and major health concern.While excessive daytime sleepiness(EDS)is a common symptom of HFD-induced obesity,preliminary findings suggest that reduced wakefulness...
supported by“the Fundamental Research Funds for the Central Universities”Starting fund(grant 71013Y2156)to Hong Jiang.
Gamma-aminobutyric acid(GABAergic)neuron,as one of important cell types in synaptic transmission,has been widely involved in central nervous system(CNS)regulation of organismal physiologies including cognition,emotion...
Objective: To determine whether patients with unresponsive wakefulness syndrome respond to auditory stimuli based on changes in facial expressions. Participants: Six patients diagnosed with disorders of consciousness ...
Neuropeptide S(NPS)is a neuromodulator that concentratively expressed in the Kolliker Fuse nucleus(KF)and pericoerulear area(Peri-LC)in mice.NPS and its receptor(NPSR)system participates multiple biological effects.Th...
supported by the Department of Science and Technology-Cognitive Science Initiative project funded to Sushil K Jha;support from Department of Biotechnology (DBT), Department of Science and Technology(PURSE), Universities for Potential of Excellence (UPOE Ⅱ) and University Grants Commission-Special Assistance Programme);JNU funds to Sushil K Jha。
The locus coeruleus(LC) is one of the essential chemoregulatory and sleep–wake(S–W) modulating centers in the brain. LC neurons remain highly active during wakefulness, and some implicitly become silent during rapid...