ANTI-ANGIOGENIC

作品数：50被引量：145H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：赵改平王晨曦陈二云更多>>
相关机构：上海理工大学复旦大学附属肿瘤医院更多>>
相关期刊：《Science China(Life Sciences)》《Nano-Micro Letters》《Chinese Journal of Natural Medicines》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金上海市教育委员会重点学科基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Unique anti-angiogenic effects,pharmacological targets and therapeutic mechanisms of Chinese herbal medicines for endometriosis
《Genes & Diseases》2024年第5期63-65,共3页Bo Liang Rui Dong Sze Wan Hung Yiran Li Yuezhen Lin Ling Wu Tao Zhang Gene Chi Wai Man Hui Xu Jacqueline Pui Wah Chung Chi Chiu Wang 
the Strategic Seed Funding for Collaborative Research Scheme(SSFCRS)of the Chinese University of Hong Kong(CUHK,China)(No.0670/22);the National Natural Science Foundation of China(No.82260948).
Endometriosis is a common and benign angiogenesisdependent gynecological disorder,which refers to the proliferation and growth of endometrium-like tissues with neovasculature formation outside of the uterus.1 Availabl...
关键词：THERAPEUTIC ENDOMETRIOSIS HERBAL 
Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy被引量：1
《Asian Journal of Pharmaceutical Sciences》2024年第2期170-187,共18页Bao Li Haoran Niu Xiaoyun Zhao Xiaoyu Huang Yu Ding Ke Dang Tianzhi Yang Yongfeng Chen Jizhuang Ma Xiaohong Liu Keda Zhang Huichao Xie Pingtian Ding 
supported by Guangdong Basic and Applied Basic Research Foundation(2023A1515010969);Natural Science Foundation of Top Talent of SZTU(GDRC202305).
Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target ...
关键词：ANTI-ANGIOGENESIS Tumor apoptosis Nanoparticles VEGF siRNA Hypoxia inducible factor(HIF)-1 protein Phenethyl isothi ocyanate(PEITC) 
Multimodal 4-arylchromene derivatives with microtubule-destabilizing,anti-angiogenic,and MYB-inhibitory activities
《Cancer Drug Resistance》2023年第1期59-77,共19页Leonhard H.F.Kohler Sebastian Reich Maria Yusenko Karl-Heinz Klempnauer Gerrit Begemann Rainer Schobert Bernhard Biersack 
supported by the Wilhelm-Sander-Stiftung(grant 2020.071.1).
Aim:Efficient and readily available anticancer drugs are sought as treatment options.For this reason,chromene derivatives were prepared using the one-pot reaction and tested for their anticancer and anti-angiogenic pr...
关键词：CHROMENE PYRAN anticancer drugs MICROTUBULE angiogenesis MYB inhibition 
Angiogenesis in hepatocellular carcinoma:mechanisms and anti-angiogenic therapies被引量：21
《Cancer Biology & Medicine》2023年第1期25-43,共19页Changyu Yao Shilun Wu Jian Kong Yiwen Sun Yannan Bai Ruhang Zhu Zhuxin Li Wenbing Sun Lemin Zheng 
supported by the National Key Research and Development Program of China(Grant No.2020YFA0803700);the National Natural Science Foundation of China(Grant Nos.91639108,81770272,and 81970425);the Beijing Natural Science Foundation(Grant No.7212044);the Beijing Hospital Authority Youth Program(Grant No.QML20190306)。
Hepatocellular carcinoma(HCC)is the fourth leading cause of cancer-associated death worldwide.Angiogenesis,the process of formation of new blood vessels,is required for cancer cells to obtain nutrients and oxygen.HCC ...
关键词：ANGIOGENESIS hepatocellular carcinoma pro-angiogenic factors tumor microenvironment anti-angiogenic therapy 
Treatment-related adverse events of combined anti-angiogenic and immune checkpoint inhibitors:systematic review and meta-analysis
《Oncology and Translational Medicine》2022年第6期301-310,共10页Lian Chen Ling Wu Zhang Lu Qin Huang Liu Huang 
Objective Immune checkpoint inhibitor(ICI)plus angiogenesis inhibitor(AI)combination therapy is a novel treatment model for multiple cancers that normalizes vascular-immune crosstalk to potentiate cancer immunity.In t...
关键词：combination therapy immune checkpoint inhibitor angiogenesis inhibitor treatment-related adverse events systematic review META-ANALYSIS 
Anti-Angiogenic and Anti-Metastatic Effects of Biogenic Silver Nanoparticles Synthesized Using Azadirachta indica
《Advances in Bioscience and Biotechnology》2022年第4期188-206,共19页Shedrack Reuben Kitimu Peter Kirira Ahmed A. Abdille Judith Sokei Dominic Ochwang’i Peter Mwitari Andrew Makanya Naomi Maina 
Background: Nanotechnology symbolizes a broad discipline with enormous potential in cancer treatment bridging one of the bottlenecks of traditional approaches in cancer therapy which is an inability to deliver adequat...
关键词：Biogenic AgNPs Cancer ANGIOGENESIS METASTASIS CAM 
Anti-Inflammatory and Anti-Angiogenic Properties of VitD3 in Ovarian Cancer
《Proceedings of Anticancer Research》2022年第2期1-5,共5页Nafiseh Saghafi Elham Abdollahi Mahsa Khajouee 
Ovarian malignancies are the most complicated type among all gynecological cancers.Their etiology is yet unknown;however,they are a heterogeneous,rapidly growing,and very fatal group of cancers.Chronic inflammation an...
关键词：VITD3 Ovarian cancer INFLAMMATION ANGIOGENESIS 
Characterization and validation of a chronic retinal neovascularization rabbit model by evaluating the efficacy of anti-angiogenic and anti-inflammatory drugs
《International Journal of Ophthalmology(English edition)》2022年第1期15-22,共8页Sandeep Kumar John Quach Nicholas Cook Glenwood Gum Vatsala Naageshwaran 
AIM:To establish a rabbit model with chronic condition of retinal neovascularization(RNV)induced by intravitreal(IVT)injection of DL-2-aminoadipic acid(DL-AAA),a retinal glial(Mül er)cell toxin,extensive characteriza...
关键词：DL-2-aminoadipic acid chronic wet agerelated macular degeneration retinal neovascularization animal model anti-vascular endothelial growth factor drugs fluorescein angiography 
Research Progress of Anti-Tumor Angiogenesis in Traditional Chinese Medicine被引量：1
《Proceedings of Anticancer Research》2021年第6期30-33,共4页Tao Gou Hailong Si 
In recent years,seeking effective anti-angiogenic components and therapeutic methods from traditional Chinese Medicine(TCM)has been a hot spot in the treatment of malignant tumors.In particular,the active ingredients ...
关键词：Traditional Chinese medicine TUMOR ANTI-ANGIOGENIC OVERVIEW 
Synthetic anti-angiogenic genomic therapeutics for treatment of neovascular age-related macular degeneration
《Asian Journal of Pharmaceutical Sciences》2021年第5期623-632,共10页Jing Wang Xiang Shi Qiyu Bo Hong Wang Fang Wei Jun Liu Hao Wang Liuwei Zhang Yan Qi Zhen Li Qixian Chen Xiaodong Sun 
funded by National Natural Science Foundation of China(81900869,81730026,81802482);National Key R&D Program(2019YFC0840607,2017YFA0105301);Science and Technology Commission of Shanghai Municipality(17411953000,19495800700);Shanghai Sailing Program(19YF1439500);Talent Project of Revitalizing Liaoning(XLYC1807184);Dalian Science&Technology Innovation Fund(2020JJ26SN050)。
In light of the intriguing potential of anti-angiogenic approach in suppressing choroidal neovascularization, we attempted to elaborate synthetic gene delivery systems encapsulating anti-angiogenic plasmid DNA as alte...
关键词：Age-related macular degeneration ANTI-ANGIOGENESIS Gene therapy Polymer Vascular endothelial growth factor 
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