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作品数：102被引量：184H指数：7
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Protective effect of marine animal hydrolysis-peptides on adjuvant-induced arthritis in mice by gut microbiota and short-chain fatty acids
《Food Science and Human Wellness》2025年第1期361-370,共10页Zhen Zhang Shasha Tang Ziyan Wang Jiaojiao Han Jun Zhou Chenyang Lu Bin Liu Xiaoling Sun Rongxian Yu Rixin Wang Xiurong Su 
sponsored by the National Key R&D Program of China(2019YFD0900101);One Health Interdisciplinary Research Project,Ningbo University,KC Wong Magna Fund in Ningbo University;the National Natural Science Foundation of China(42106122);the Natural Science Foundation of Zhejiang Province(LGC22C190002)。
Marine fauna provides a plentiful repository of peptides and bioactive proteins.Peptides and proteins isolated from marine animals have been studied and applied in the development of food supplements,drugs,and cosmece...
关键词：Marine animals-derived peptides Adjuvant-induced arthritis Gut flora Short-chain fatty acid 
αB-crystallin mini-peptides support corneal healing in vitro and in vivo in rabbit model
《International Journal of Ophthalmology(English edition)》2024年第10期1772-1779,共8页Namrata Maity Aditya Konar Sarbani Hazra 
Supported by the DST Nano-mission,Govt of India,Grant No DST No.SR/NM/NS-1067/2016;Facilities were provided by the West Bengal University of Animal&Fishery Sciences and CSIR-IICB for conducting this research。
AIM:To evaluate if topical use of αB-crystallin minipeptides supports corneal healing following flap surgery.METHODS:Cultured corneal cells were treated with fluorescent taggedαB-crystallin mini-peptides to assess i...
关键词：corneal healing αB-crystallin CYTOPROTECTION NEUROPROTECTION 
Carrier-free cryptotanshinone-peptide conjugates self-assembled nanoparticles:An efficient and low-risk strategy for acne vulgaris
《Asian Journal of Pharmaceutical Sciences》2024年第4期85-102,共18页Quanfu Zeng Hongkai Chen Zhuxian Wang Yinglin Guo Yufan Wu Yi Hu Peiyi Liang Zeying Zheng Tao Liang Dan Zhai Yaling Guo Li Liu Chunyan Shen Cuiping Jiang Qun Shen Yankui Yi Qiang Liu 
Acne vulgaris ranks as the second most prevalent dermatological condition worldwide,and there are still insufficient safe and reliable drugs to treat it.Cryptotanshinone(CTS),a bioactive compound derived from traditio...
关键词：Carrier-free CRYPTOTANSHINONE Self-assembly ACNE 
Pull the fuzes:Processing protein precursors to generate apoplastic danger signals for triggering plant immunity
《Plant Communications》2024年第8期113-136,共24页Daniele Del Corpo Daniele Coculo Marco Greco Giulia De Lorenzo Vincenzo Lionetti 
supported by Sapienza University of Rome,grants RM120172 B78CFDF2,RM11916B7A142CF1,RM122181424F1F42,and RG12117 A898EABE0;by the European Union“NextGenerationEU”program“Project ECS 0000024 Rome Technopole”-CUP B83C22002820006,PNRR Missione 4 Componente 2 Investimento 1.5;by the Italian Ministry for Education,University and Research(MUR)with the project REACH-XY:CUP B93C22001920001.
The apoplast is one of the first cellular compartments outside the plasma membrane encountered by phytopathogenic microbes in the early stages of plant tissue invasion.Plants have developed sophisticated surveillance ...
关键词：APOPLAST immunity activation post-translational processing cell wall proteases pro-peptides proenzymes phytocytokines cell-wall remodeling enzymes phytopathogenic microbes plant immunity 
Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing被引量：1
《Cellular & Molecular Immunology》2024年第4期362-373,共12页Zeguang Wu Qiezhong Lamao Meichao Gu Xuanxuan Jin Ying Liu Feng Tian Ying Yu Pengfei Yuan Shuaixin Gao Thomas S.Fulford Adam P.Uldrich Catherine C.L Wong Wensheng Wei 
funding from the National Science Foundation of China(31930016);the Peking-Tsinghua Center for Life Sciences;ZW received funding from the State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases(2024KF00001);the National Science Foundation of China(82350119);CCW received funding from the Talent Introduction Funds from the Chinese Academy of Medical Science(2022-RC310-10);the National Science Foundation of China(32150005);the Research Funds from Health@InnoHK Program,launched by the Innovation Technology Commission of the Hong Kong Special Administrative Region.
Vγ9Vδ2 T cells are specialized effector cells that have gained prominence as immunotherapy agents due to their ability to target and kill cells with altered pyrophosphate metabolites.In our effort to understand how ...
关键词：BUTYROPHILIN Vγ9Vδ2 T-cell Cancer-specific immune evasion Glutaminyl-peptide cyclotransferase-like Pyrophosphate metabolite Immunotherapy 
Glucagon-like-peptide-1 receptor agonists and the management of type 2 diabetes-backwards and forwards
《World Journal of Diabetes》2024年第3期326-330,共5页Michael Horowitz Lu Cai Md Shahidul Islam 
This editorial is stimulated by the article by Alqifari et al published in the World Journal of Diabetes(2024).Alqifari et al focus on practical advice for the clinical use of glucagon-like-peptide-1(GLP-1)receptor ag...
关键词：Glucagon-like-peptide-1 Glucose-dependent insulinotropic peptide Gastric emptying Type 2 diabetes 
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein(QPCTL)with antitumor efficacy
《Signal Transduction and Targeted Therapy》2024年第1期44-46,共3页Lei Yu Pengcheng Zhao Yaoliang Sun Zening Zheng Wenhao Du Lishan Zhang Yaxu Li Longyan Xie Shilin Xu Ping Wang 
was supported by grants from the National Natural Science Foundation of China(2220708,82341028,82103973);Shanghai Sailing Program(22YF1433500,22YF1457500);Key R&D Projects in Ningxia Hui Autonomous Region(2021BFH03001).
Dear Editor,Immune checkpoint therapies manipulating the immune system to eliminate tumor cells have shown remarkable clinical efficacy in treating various cancers.CD47,an emerging efficient immune checkpoint,is cruci...
关键词：ANEMIA OVERCOME eliminate 
Host-Defense-Peptide-Mimickingβ-Peptide Polymer Acting as a Dual-Modal Antibacterial Agent by Interfering Quorum Sensing and Killing Individual Bacteria Simultaneously被引量：3
《Research》2023年第4期245-261,共17页Wanlin Li Ximian Xiao Yuchen Qi Xiuhui Lin Huiqun Hu Minqi Shi Min Zhou Weinan Jiang Longqiang Liu Kang Chen Kai Wang Runhui Liu Min Zhou 
This work was supported by the National Natural Science Foundation of China(nos.81971667,22075078,and 21861162010);the National Natural Science Foundation of China for Innovative Research Groups(no.51621002);the Key Research and Development Project of Zhejiang Province(no.2020C03035);the Fundamental Research Funds for the Zhejiang Provincial Universities,China(no.2021XZZX034).
Host defense peptides(HDPs)are one of the potentially promising agents for infection diseases due to their broad spectrum and low resistance rate,but their clinical applications are limited by proteolytic instability,...
关键词：process KILLING MODAL 
Atligator Web:A Graphical User Interface for Analysis and Design of Protein-Peptide Interactions
《BioDesign Research》2023年第1期80-85,共6页Josef Paul Kynast Birte Höcker 
the European Research Council H2020-FETopenRIA grant 764434“PRe-ART”and the EIC Transition grant 10105802“PRe-ART-2T”.
A key functionality of proteins is based on their ability to form interactions with other proteins or peptides.These interactions are neither easily described nor fully understood,which is why the design of specific p...
关键词：WEB SERVER intuitive 
Formulated nano-liposomes for reversal of cisplatin resistance in NSCLC with nucleus-targeting peptide
《Nano Research》2023年第11期12864-12879,共16页Minxian Li Mei Jiang Mengting Chen Lilusi Ma Xiaocui Fang Yanlian Yang Chen Wang 
supported by the National Natural Science Foundation of China(Nos.32101130,21721002,and 31971295);Financial support from Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000)is also gratefully acknowledged.
Cell membrane-engineered nano-delivery systems have evolved as a promising strategy to enhance drug bioavailability,offering an alternative for reversing drug resistance in cancer therapy.Herein,a formulated nano-lipo...
关键词：formulated liposome tumor homing cisplatin resistance nucleus-peptide cancer therapy 
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