the National Natural Science Foundation of China(31730067,31801472);the national first-class discipline program of Light Industry Technology and Engineering(LITE2018-03).
Nigerose is a kind of rare disaccharide connected by anα-1,3 glucosidic bond,which is a potential probiotic due to its antidigestive properties and beneficial functions.This study identified and characterized a novel...
supported by the European Union’s Horizon 2020 research and innovation program(GoodBerry;grant agreement number 679303);Agencia Estatal de Investigación(PID2019-111496RR-I00/AEI/10.13039/501100011033)and PR.AVA.AVA2019.034(IFAPA,FEDER funds)。
Strawberry(Fragaria×ananassa)fruits are an excellent source of L-ascorbic acid(AsA),a powerful antioxidant for plants and humans.Identifying the genetic components underlying AsA accumulation is crucial for enhancing...
Initially it was believed that phosphorylase was responsible for both glycogen breakdown and synthesis in the living cell.The discovery of glycogen synthase and McArdle's disease(lack of phosphorylase activity),togeth...
supported by the National Science Foundation of China(Grant No.3197150429).
OsPho1 in Zhonghua 11(ZH11)was edited using the clustered regularly interspaced short palindromic repeatsassociated endonuclease 9(CRISPR/Cas9)system.Two homozygous T1 mutants(cr-pho1-34 and cr-pho1-37)displayed a cha...
This work was supported by the Key Research Program of the Chinese Academy of Sciences(Grant No.ZDRW-ZS-2016-3);the National Natural Science Foundation of China(Grant No.21778073);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(Grant No.TSBICIP-KJGG-003).
Disaccharide phosphorylases(DSPs)are carbohydrate-active enzymes with outstanding potential for the biocatalytic conversion of common table sugar into products with attractive properties.They are modular enzymes that ...
the DST-SERB Major Research Project,New Delhi,India[Project File No.SB/YS/LS-109/2014]for funding this project;the Management of A.V.V.M.Sri Pushpam College(Autonomous);Poondi,and Sharmila Institute of Medicinal Products Research Academy(SIMPRA);Thanjavur,India,for providing necessary facilities and support in carrying out this work
In this study, molecular interactions of the ligands, quercetin, gallic acid, and metformin with various diabetes mellitus-related protein targets, such as glycogen phosphorylase and peroxisome proliferatoractivated r...
During exercise, phosphorylase kinase (PhK) is the key regulatory enzyme responsible for maintaining glycogenolytic flux to sustain muscle contraction. The absence of PhK in skeletal muscle results in glycogen storage...
Thymidine phosphorylase (TP) is a key enzyme that contributes to the composition and decomposition of pyrimidine nucleotides. TP seems homologous to platelet-derived endothelial cell growth factor, and its effects on ...
Purine Nucleoside Phosphorylase (PNP) deficiency is a rare autosomal recessive metabolic disorder. In PNP-deficiency disorder, the deficient enzyme leads to accumulation of toxic metabolites, especially in lymphocytes...
Background: Phosphorylase kinase (PhK) activity is induced by injurious stimuli, which is known to precipitate psoriasis. We had previously reported that elevated PhK activity in psoriatic epidermis correlated with in...