GLUCOSIDES

作品数：55被引量：222H指数：7
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相关领域：医药卫生理学更多>>
相关作者：郑志富周燮戴敏郑咏秋沈玉先更多>>
相关机构：南京农业大学安徽医科大学安徽中医学院中国科学院上海生命科学研究院更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金：国家自然科学基金安徽省自然科学基金国家高技术研究发展计划国家重点基础研究发展计划更多>>
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Total glucosides of paeony alleviates cGAS-STING-mediated diseases by blocking the STING-IRF3 interaction
《Chinese Journal of Natural Medicines》2024年第5期402-415,共14页XIU Ye WANG Sihao ZHANG Ping LI Chengwei WU Zhixin WEN Jincai XU Yingjie LV Guiji ZHAO Xiaomei DONG Xu CHEN Yichong LI Junjie WANG Yan ZOU Liang XIAO Xiaohe BAI Zhaofang 
This work was supported by the Natural Science Foundation of Beijing(No.7232321);the Cultivating and Improving the Service Ability of Traditional Chinese Medicine(No.2021ZY038);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202005);the State Key Program of National Natural Science of China(Nos.81930110,82230118)。
In the realm of autoimmune and inflammatory diseases,the cyclic GMP-AMP synthase(cGAS)stimulator of interferon genes(STING)signaling pathway has been thoroughly investigated and established.Despite this,the clinical a...
关键词：Total glucosides of gaeony cGAS-STING pathway Inflammation LPS/D-GalN STING inhibitor 
Total glucosides of Rhizoma Smilacis Glabrae:a therapeutic approach for psoriasis by regulating Th17/Treg balance被引量：4
《Chinese Journal of Natural Medicines》2023年第8期589-598,共10页TANG Yingzhan YU Jingyi ZHAO Wen LIU Juyan PENG Hongying ZHANG Haoran JIANG Zhenzhou YU Qinwei ZHANG Luyong 
supported by the National Natural Science Foundation of China(Nos.82074114,81973562 and 81773995),the Scholar of the 14th batch of“Six Talents Peak”highlevel talent selection(No.SWYY-094);the“Double First-Class”University project(No.CPU2018GY33).
Total glucosides of Rhizoma Smilacis Glabrae(RSG)are selective immunosuppressants that exhibit primary efficacy in the treatment of rheumatoid arthritis through targeted inhibition of activated T cells.In this study,w...
关键词：PSORIASIS Rhizoma Smilacis Glabrae Th17/Treg balance Inflammation Epithelium development 
Enzyme-like C-H Oxidation of Glucosides Promoted by Visible Light被引量：1
《CCS Chemistry》2022年第11期3599-3608,共10页Mingzhong Wu Qian Jiang Qiong Tian Tianyun Guo Feng Cai Shouchu Tang Jian Liu Xiaolei Wang 
Financial support for this work was provided by the National Science Foundation of China(grant no.22071087);the Fundamental Research Funds for the Central Universities(grant no.lzujbky-2021-ct05);the Open Projects Funds of Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology,Shandong University(grant no.2019CCG05).X.W.also thanks the Thousand Young Talents Program and Longyuan Talents Program for financial support.
To match nature’s prowess at using enzymes to make desired motifs in a regioselective fashion,we explore the use of visible light for the selective oxidation of the hydroxyl group to afford the corresponding ketosacc...
关键词：keto-saccharide selective oxidation unprotected glucoside VISIBLE-LIGHT 
Mechanism of total glucosides from Chishao(Radix Paeoniae Rubra)on proliferation and apoptosis of hepatocellular carcinoma cells via phosphatase and tensin homolog deleted on chromosome ten/phosphatidylinositol 3-kinase/protein kinase B signaling pathway
《Journal of Traditional Chinese Medicine》2021年第5期677-683,共7页FAN Bingbing LI Tianjiao MENG Xiansheng WANG Shuai BAO Yongrui WANG Fei 
Supported by National Natural Science Foundation of China:Study on the Method of Discovering Active Substance in Anti-liver Cancer of Oroxylum Indicum Based on Microfluidic Cell Biological Chip Technology(No.81874342);Supported by National Key R&D Program of China:Take Bufei Jianpi Formula as a Model to Study the Material Basis and Mechanism of Improving COPD(SQ2018YFC170161);the Project of Pnnovation Team of Liaoning Province:Innovative Team of Integrated Research on Pharmacodynamic Metabonomics and Mechanism of Traditional Chinese Medicine(No.LT2017015)。
OBJECTIVE:To investigate the possible molecular mechanism of total glycosides of Chishao(Radix Paeoniae Rubra)(TG-RPR)on proliferation and apoptosis of hepatocellular carcinoma cells.METHODS:The proliferation of TG-RP...
关键词：carcinoma hepatocellular GLYCOSIDES PTEN phosphohydrolase phosphatidylinositol 3-kinase proto-oncogene proteins c-akt Chishao(Radix Paeoniae Rubra) 
Termitomenins F and G,Two New Lignan Glucosides from Terminalia chebula var.tomentella(Kurz)C.B.Clarke被引量：1
《Natural Products and Bioprospecting》2021年第5期565-572,共8页Jun Yin Hong‑Tao Zhu Man Zhang Dong Wang Chong‑Ren Yang Ying‑Jun Zhang 
The extensive chemical investigation on the branches and leaves of Terminalia chebula var.tomentella(Combretaceae)led to the isolation of two new lignan glucosides with a furofuran skeleton,termitomenins F(1)and G(2)....
关键词：Terminalia chebula var.tomentella Lignan glucosides Hydrolyzable tannins α-Glucosidase inhibitory activity Calculated ECD 
Chemical Constituents from the Whole Plant of Cuscuta reflexa
《Natural Products and Bioprospecting》2020年第5期337-344,共8页Tin Thu Thu Aung Meng-Yuan Xia Pyae Phyo Hein Rong Tang Dong-Dong Zhang Jun Yang Xue-Fei Yang Dong-Bao Hu Yue-Hu Wang 
supported by the Southeast Asia Biodiversity Research Institute,Chinese Academy of Sciences(Grant Nos.2015CASEABRIRG001 and Y4ZK111B01);the International Partnership Program of Chinese Academy of Sciences(Grant No.153631KYSB20160004);the National Natural Science Foundation of China(31960480);the Joint Special Project of Local Undergraduate Universities in Yunnan Province,China(Grant No.2018FH001-024);the Second Tibetan Plateau Scientific Expedition and Research(STEP)Program of Ministry of Science and Technology of the People’s Republic of China(Grant No.2019QZKK0502).
Two new 2H-pyran-2-one glucosides,cuscutarosides A(1)and B(2),and one new steroidal glucoside,7β-methoxy-β-sitosterol 3-O-β-glucopyranoside(3),together with 12 known compounds(4-15)were isolated from the whole plan...
关键词：Cuscuta reflexa Porcine pancreatic lipase Platelet aggregation 2H-pyran-2-one glucosides Steroidal glucosides 
Erratum to:Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae
《Current Medical Science》2020年第3期596-596,共1页Wen-jing WANG Chong DAI Jian-ping WANG Hu-cheng ZHU Chun-mei CHEN Yong-hui ZHANG 
The article“Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae”,written by Wen-jing WANG,Chong DAI,Jian-ping WANG,Hu-cheng ZHU,Chun-mei CHEN,Yong-hui ZHANG,was originally published elec...
关键词：SUBSTITUTED LICENSE CHONG 
Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae
《Current Medical Science》2020年第2期232-238,共7页Wen-jing WANG Chong DAI Jian-ping WANG Hu-cheng ZHU Chun-mci CHEN Yong-hui ZHANG 
This work was financially supported by the Program for Changjiang Scholars of Ministry of Education of the People's Republic of China(No.T2016088);the National Natural Science Foundation for Distinguished Young Scholars(No.81725021);the National Natural Science Foundation of China(No.31900288);the Program from the(hina Postdoctoral Science Foundation(No.2019M652660);the Integrated Innovative Team for Major Human Diseases Program of Tongji Medical College(HUST,China).
MetarhizosidesA-G(1-7),seven new polysubstituted phenyl glucosides,were isolated from the extracts of solid rice medium of a marine-derived fungus Metarrhizium anisopliae.Compounds 1-7 all contain a polysubstituted ph...
关键词：marine-derived fungus GLUCOSIDES Metarrhizium anisopliae ANTI-INFLAMMATION cytotoxicities 
Effect of total glucosides of peony on the proliferation,differentiation,and mineralization of MC3T3-E1 osteoblastic cells
《China Medical Abstracts(Internal Medicine)》2019年第4期198-198,共1页ZHAO Xiangrong 
Objective To observe the effect of total glucosides of peony(TGP)on the proliferation,differentiation,and mineralization of MC3 T3-E1 osteoblastic cells.Methods The effects of TGP on the proliferation and cell cycle o...
关键词：EFFECT TOTAL GLUCOSIDES 
Nickel-catalyzed reductive coupling of glucosyl halides with aryl/vinyl halides enabling β-selective preparation of C-aryl/vinyl glucosides
《Science China Chemistry》2019年第11期1492-1496,共5页JiANDong Liu Chuanhu Lei Hegui Gong 
supported by the National Natural Science Foundation of China(21871173,21572140,21372151)
This work describes stereoselective preparation ofβ-C-aryl/vinyl glucosides via mild Ni-catalyzed reductive arylation and vinylation of C1-glucosyl halides with aryl and vinyl halides.A broad range of aryl halides an...
关键词：NICKEL-CATALYZED reductive coupling β-selective PREPARATION C-aryl/vinyl GLUCOSIDES 
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