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GUANINE: 作品数：49被引量：54H指数：4; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：杨仪刘增礼杨君杨君唐军更多>>; 相关机构：浙江大学医学院附属第一医院苏州大学附属第二医院中国人民解放军北京师范大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金福建省自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>

Developing guanine base editors for G-to-T editing in rice: 《Journal of Integrative Plant Biology》2024年第8期1557-1560,共4页Lang Liu Zhongming Zhang Chenyang Wang Fang Yan Wenxian Sun Xueping Zhou Weiguo Miao Huanbin Zhou; supported by the Biological Breeding-Major Projects (2023ZD04074);the Nanfan special project of the Chinese Academy of Agricultural Sciences (YBXM2313);the Hainan Seed Industry Laboratory (B23CJ0208);the Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences。; Single nucleotide polymorphisms (SNPs) are widely present and related to desirable agronomic traits in crops.clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated nuclease 9 (Cas9)-mediated bas...; 关键词：alleles AGRONOMIC BASE

Guanine-derived F,N co-doped carbon-shell encapsulated iron carbide nanoparticles for enhanced CO_(2)electroreduction activity被引量：1: 《Nano Research》2024年第6期4744-4752,共9页Shuo Chen Lishun Pei Ying Peng Xuefei Zhang Zailai Xie; the financial support from the National Natural Science Foundation of China(Nos.22072018 and 22372039);the Natural Science Foundation of Fujian Province of China(No.2021J06010).; The development of highly selective,cost-effective,and energy-efficient electrocatalysts is critical for carbon dioxide reduction reaction(CO_(2)RR)to produce high-value products.Herein,we propose a facile strategy to...; 关键词：GUANINE F N co-doped carbon dioxide reduction reaction(CO_(2)RR) Fe-based catalyst

A tetrahedral framework nucleic acid based multifunctional nanocapsule for tumor prophylactic mRNA vaccination被引量：2: 《Chinese Chemical Letters》2023年第7期169-175,共7页Yuhao Liu Songhang Li Shiyu Lin Sirong Shi Taoran Tian Bowen Zhang Tao Zhang Yunfeng Lin; supported by National Key R&D Program of China (No. 2019YFA0110600);National Natural Science Foundation of China (No. 81970916);Sichuan Province Youth Science and Technology Innovation Team (No. 2022JDTD0021);Research Funding from West China School/Hospital of Stomatology Sichuan University (No. RCDWJS2021-20);China Postdoctoral Science Foundation (No. 2022TQ0381)。; Synthetic antigen-encoding mRNA plays an increasingly significant role in tumor vaccine technology owing to its antigen-specific immune-activation. However, its immune efficacy is challenged by inferior delivery effic...; 关键词：Tetrahedral framework nucleic acid(tFNA) RNA nanovaccine Cytosine-phosphate-guanine(CpG)motifs Murineβ-defensin 2(mDF2β) Tumor immunotherapy

Hierarchical Self-assembly of G-Quadruplexes Based Hydrogel Consisting of Guanine and Peptide Epitope被引量：1: 《Chinese Journal of Chemistry》2023年第14期1727-1732,共6页Hongyue Zhang Xuejiao Yang Juan Liang Kaihua Chen Huaimin Wang; supported by the National Natural Science Foundation of China(82022038)。; Guanosine-based hydrogels have attracted considerable attention because of their simplicity and easy preparation.However,the sugar moiety limits its further applications because of the necessity of sugar in the hydrog...; 关键词：G-QUADRUPLEXES Peptides NUCLEOBASES SELF-ASSEMBLY HYDROGELS Cell culture

Guanine-regulated proton transfer enhances CO_(2)-to-CH_(4) selectivity over copper electrode: 《Chinese Journal of Catalysis》2022年第12期3101-3106,共6页Jun Gong Jinmeng Li Chang Liu Fengyuan Wei Jinlong Yin Wenzheng Li Li Xiao Gongwei Wang Juntao Lu Lin Zhuang; 国家自然科学基金(21991154,21991150,92045302,22172115,21902120);中央高校基本研究基金(2042021kf1064).; Electrocatalytic CO_(2) reduction has attracted growing attention as a promising route to realize artificial carbon recycling.Proton transfer plays an essential role in CO_(2) reduction and dramatically impacts produc...; 关键词：CO_(2)electroreduction Surface modification GUANINE Proton transfer METHANE Copper

DNA/RNA helicase DHX36 is required for late stages of spermatogenesis: 《Journal of Molecular Cell Biology》2022年第11期50-61,共12页Kejia Zhang Tianxin Zhang Yujie Zhang Jinyu Yuan Xinzhe Tang Chaobao Zhang Qianqian Yin Yonglian Zhang Ming-Han Tong; supported by grants from the National Key R&D Program of China(2021YFC2700200 and 2022YFC2702602);the National Natural Science Foundation of China(31930034);the Science and Technology Commission of Shanghai Municipality(19JC1415800 to M.-H.T.).; Spermatogenesis is a highly complex developmental process that typically consists of mitosis, meiosis, and spermiogenesis. DNA/RNA helicase DHX36, a unique guanine-quadruplex (G4) resolvase, plays crucial roles in a v...; 关键词：Dhx36 MEIOSIS guanine-quadruplex(G4) Spo11 SYNAPSIS meiotic recombination crossover

DNA and RNA oxidative damage in hepatocellular carcinoma patients and mortality during the first year of liver transplantation: 《World Journal of Hepatology》2022年第6期1182-1189,共8页Leonardo Lorente Sergio T Rodriguez Pablo Sanz Agustín F González-Rivero Antonia Pérez-Cejas Javier Padilla Dácil Díaz Antonio González María M Martín Alejandro Jiménez Purificación Cerro Julián Portero Manuel A Barrera; BACKGROUND Oxidative damage of DNA and RNA has been associated with mortality of patients with different diseases.However,there is no published data on the potential use of DNA and RNA oxidative damage to predict the ...; 关键词：DNA oxidative damage Hepatocellular carcinoma Liver transplantation MORTALITY Oxidized guanine species

Molecular Similarity within Carcinogen and Guanine Cyclic Nucleotide Structures: 《Journal of Biosciences and Medicines》2022年第5期86-94,共9页Wynford Robert Williams; Tumor promoters, apoptosis and autophagy modulators, chemotherapy drugs, and endogenous steroids demonstrate molecular similarity relative to cyclic nucleotide structure. This study explores relative molecular similar...; 关键词：ANESTHETICS Cancer CARCINOGENS Guanosine Cyclic Monophosphate Molecular Similarity

Guanine-assisted N-doped ordered mesoporous carbons as efficient capacity decaying suppression materials for lithium–sulfur batteries: 《Journal of Materials Science & Technology》2022年第6期155-164,共10页Riguang Cheng Yanxun Guan Yumei Luo Chenchen Zhang Yongpeng Xia Sheng Wei Mengmeng Zhao Qi Lin Hao Li Shiyou Zheng Federico Rosei Lixian Sun Fen Xu Hongge Pan; financially supported by the National Key Research and Development Program of China(2018YFB1502103,2018YFB1502105);the National Natural Science Foundation of China(Grant Nos.U20A20237,51871065 and 51971068);the Scientific Research and Technology Development Program of Guangxi(AA19182014,AD17195073 and AA17202030–1);Guangxi Bagui Scholar Foundation;Guangxi Collaborative Innovation Centre of Structure and Property for New Energy and Materials;Guangxi Advanced Functional Materials Foundation;Application Talents Small Highlands;Chinesisch–Deutsche Kooperationsgruppe(GZ1528);the Canada Research Chairs program for partial salary support;the Guangxi undergraduate innovation and entrepreneurship training program(202010595272)。; Lithium–sulfur(Li–S)batteries are considered promising next-generation energy storage devices due to their high weight capacities and theoretical energy densities,which are significantly higher than those of convent...; 关键词：Lithium–sulfur batteries N-doped ordered mesoporous carbons ELECTROCHEMISTRY

The catalytic properties of DNA G‐quadruplexes rely on their structural integrity: 《Chinese Journal of Catalysis》2021年第7期1102-1107,共6页Jielin Chen Mingpan Cheng Jiawei Wang Dehui Qiu David Monchaud Jean‐Louis Mergny Huangxian Ju Jun Zhou; 国家自然科学基金(21977045,21635005);中央高校基本科研业务费(02051430210);南京大学高层次人才科研启动经费(020514912216).; The influence of the G‐quartet structural integrity on the catalytic activity of the G‐quadruplex(G4)was investigated by comparing the G4‐DNAzyme performances of a series of G4s with a G‐vacancy site and a G‐trip...; 关键词：G‐quadruplex G‐quadruplex DNAzyme G‐vacancy G‐quartet integrity Guanine surrogate

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