SPHINGOSINE

作品数：80被引量：236H指数：8
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相关领域：医药卫生更多>>
相关作者：张翼肖琼尹大力徐美林王菁更多>>
相关机构：北京协和医学院首都医科大学天津市胸科医院天津医科大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/stem cells被引量：2
《World Journal of Stem Cells》2018年第9期119-133,共15页Mei Li Ng Nagendra S Yarla Mario Menschikowski Olga A Sukocheva 
Balanced sphingolipid signaling is important for the maintenance of homeostasis. Sphingolipids were demonstrated to function as structural components, second messengers, and regulators of cell growth and survival in n...
关键词：Sphingosine-1-phosphate SPHINGOLIPIDS Embryonic STEM CELLS Mesenchymal STEM CELLS Bone marrow hematopoietic STEM CELLS SPHINGOSINE kinase PROGENITOR 
Sphingolipids in cardiovascular and cerebrovascular systems:Pathological implications and potential therapeutic targets
《World Journal of Cardiology》2013年第4期75-86,共12页Masahito Kawabori Rachid Kacimi Joel S Karliner Midori A Yenari 
Supported by Grants from the National Institutes of Health (NS40516,to Yenari MA);the Veteran's Merit Award(Yenari MA);the Uehara Foundation(2013 Research Fellowship,to Kawabori M);the National Heart,Lung,and Blood Institute/NHLBI(1P01 HL 68738 and R01 HL 090606 to Karliner JS);Grants to Yenari MA and Karliner JS were administered by the Northern California Institute for Research and Education;supported by resources of the Veterans Affairs Medical Center, San Francisco,California
The sphingolipid metabolites ceramide,sphingosine,and sphingosine-1-phosphate(S1P) and its enzyme sphingosine kinase(SphK) play an important role in the regulation of cell proliferation,survival,inflammation,and cell ...
关键词：SPHINGOLIPIDS Sphingosine-1-phosphate SPHINGOSINE KINASE CERAMIDE KINASE 
Sphk1 Expression and Survival Outcomes in Squamous Cell Carcinoma of the Oral Cavity
《Journal of Cancer Therapy》2013年第3期704-708,共5页Brianna N. Harris Rizwan Masood Uttam K. Sinha 
Sphingosine kinase 1 (SphK1) is an important mediator of apoptosis and the proliferation of cancer cells. It is upregulated in cells showing increasing radioresistance. Here we present the correlation between SphK1 ex...
关键词：SPHINGOSINE KINASE 1 SQUAMOUS Cell CARCINOMA Radiation SPHINGOLIPIDS ORAL Cavity 
Overexpression of Rice Sphingosine-1-Phoshpate Lyase Gene OsSPL1 in Transgenic Tobacco Reduces Salt and Oxidative Stress Tolerance被引量：5
《Journal of Integrative Plant Biology》2012年第9期652-662,共11页Huijuan Zhang Jing Zhai Jibo Mo Dayong Li Fengming Song 
supported by the National Key Project for Research on Transgenic Plants (2009ZX08001-017B and 2011ZX08009-003-001);the National Natural Science Foundation of China (No. 30971880);the National High-tech R&D Program of China (No. 2 012AA101504);the Program for Changjiang Scholars and Innovative Research Team in the University of the Ministry of Education of China (No. IRT0943)
Sphingolipids, including sphingosine-l-phosphate （SIP）, have been shown to function as signaling mediators to regulate diverse aspects of plant growth, development, and stress response. In this study, we performed f...
关键词：SPHINGOLIPIDS sphingosine-l-phosphate lyase （SPL） OsSPL1 salt stress oxidative stress. 
Regulation of cancer cell migration and invasion by sphingosine-1-phosphate被引量：4
《World Journal of Biological Chemistry》2010年第10期307-312,共6页James R Van Brocklyn 
Supported by R21 CA124685 from the National Cancer Institute;R01 NS41517 from the National Institute of Neurological Disorders and Stroke
Sphingosine-1-phosphate (S1P) is a bioactive sphingo-lipid that has been implicated in regulation of a number of cancer cell malignant behaviors, including cell proliferation, survival, chemotherapeutic resistance and...
关键词：SPHINGOLIPIDS Cancer INVASION METASTASIS 
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