核受体在细胞稳态的维持以及疾病的发生发展等方面发挥着重要的作用。为了探究核受体亚家族6A组成员1(nuclear receptor subfamily 6 group A member 1,NR6A1)在肝癌中的作用及机制,首先,分析了癌症基因组图谱(The Cancer Genome Atlas,...
This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81100764 and 81471110).
Human N-myc downstream-regulated gene 2 (NDRG2) has been shown to be a multifunctional protein associated with cell proliferation, differentiation, transmembrane transport, and stress responses. In most mammalian br...
funded by the National Natural Science Foundation of China,No.81171401;Science and Technology Development Program of Dalian City,No.2008J99JH268;the Scientific Research Program of Higher Learning School of Department of Education of Liaoning Province,No.L20100108
Proliferation of neural stem cells is regulated by the secreted signaling molecule sonic hedgehog. In this study, neural stem cells were infected with recombinant adeno-associated virus expressing sonic hedgehog-N-enh...
Using subtraction cloning, we identified the human N-Myc Downstream- Regulated Gene-2 (hNDRG2), located at 14q11.2, as a candidate tumor suppressor gene. Semi-quantitative RT-PCR showed that the expression of hNDRG2 i...