TETRAMETHYLPYRAZINE

作品数：58被引量：265H指数：9
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相关领域：医药卫生更多>>
相关作者：文志斌贺石林何晓凡庄沛张婉玉更多>>
相关机构：中南大学齐鲁工业大学天津科技大学沈阳华泰药物研究所更多>>
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  • 学科=医药卫生—药学x
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Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis被引量：7
《Asian Journal of Pharmaceutical Sciences》2018年第3期229-238,共10页Xiuping Zhang Yang Shi Zhiyue Zhang Zhenlei Yang Guihua Huang 
Tetramethylpyrazine(TMP) is a traditional Chinese herbal medicine with strong antiinflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis. However, TMP is rapidly c...
关键词：OSTEOARTHRITIS TETRAMETHYLPYRAZINE INTRA-ARTICULAR injection PLGA MICROSPHERES RETENTION PHARMACODYNAMICS 
Effect of tetramethylpyrazin combined with cisplatin on VEGF,KLF4 and ADAMTS1 in lewis lung cancer mice被引量：9
《Asian Pacific Journal of Tropical Medicine》2017年第8期874-878,共5页Jian-Hua Tang He-Min Zhang Zhi-Hua Zhang Xiu-Long Zhang 
supported by the Key Project of Medical Science of Hebei Province(No.20170185)
Objective: To further explore the function of combine use of tetramethylpyrazine(TMP) and cisplatin(DDP) in lung carcinoma. Methods: We used the combination drug to treat Lewis lung cancer mice, investigated the expre...
关键词：Non-small cell lung cancer TETRAMETHYLPYRAZINE CISPLATIN ADAMTS1 VEGF KLF4 
Tetramethylpyrazine protects lymphocytes from radiationinduced apoptosis through nuclear factor-κB被引量：7
《Chinese Journal of Natural Medicines》2014年第10期730-737,共8页WANG Xiao-Yan MA Zeng-Chun WANG Yu-Guang TAN Hong-Ling XIAO Cheng-Rong LIANG Qian-De TANG Xiang-Lin CHENG Yu GAO Yue 
supported by the National Nature Sciences Foundation of China(Nos.81073028,81130067 and 81274127)
AIM: Radiation induces an important apoptosis response in irradiated organs. The objective of this study was to investigate the radioprotective effect of tetramethylpyrazine(TMP) on irradiated lymphocytes and discover...
关键词：TETRAMETHYLPYRAZINE RADIOPROTECTION NF-κB APOPTOSIS 
The protective effect of tetramethylpyrazine （TMP） against PC12 cells damages
《Acta Pharmacologica Sinica》2004年第11期1555-1556,共2页Xin-ruiCHENG LanSUN LiZHANG Juan-juanHU Guan-HuaDU 
AIM: To discover the protective effects of tetramethylpyrazine (TMP) against PC12 cells damages and explore its protective mechanisms. METHODS: We established three in vitro models to investigate the protective effect...
关键词：PC12 TMP LDH MTT AIM 
Inhibitory effect of tetramethylpyrazine on P2X receptor-mediated excitation of nociceptive afferents
《中国药理通讯》2004年第2期57-58,共2页Shang-DongLiang YunGao Bao-HuaXu Song-NiuMu Chang-ShuiXu 
Object: In this study we investigated the effects of intrathecally administered TMP on the acute nociception mediated by the local administration of P2X receptor agonists ( ATP or α,β-meATP) or formalin in mouse hin...
关键词：抑制作用 四甲基吡嗪 P2X 受体激动剂 疼痛 传入神经 
Simultaneous Determination of Tetramethylpyrazine and Aspirin in a New Compound Formulation by Liquid Chromatography被引量：2
《Journal of Chinese Pharmaceutical Sciences》2004年第1期58-62,共5页王鹏 齐美玲 周莉 方林 
Aim To establish a reversed-phase liquid chromatographic (LC) method forsimultaneous determination of tetramethylpyrazine (TMP) and aspirin in a new compound formulation.Methods Chromatographic separation of the two d...
关键词：liquid chromatography TETRAMETHYLPYRAZINE ASPIRIN ASSAY 
Effect of tetramethylpyrazine on exocrine pancreatic and bile secretion被引量：1
《World Journal of Gastroenterology》2003年第11期2505-2508,共4页Wen-ChaoZhao Jin-XiaZhu NingTang Yu-LinGou DewiKennethRowlands Yiu-WaChung YingXing Hsiao-ChangChan 
innovation and Technology Funds of Hong Kong;strategic Program of the Chinese University of Hong Kong
AIM: To investigate the effect of tetramethylpyrazine (ligustrazine, TMP) on the secretion of exocrine pancreas (and biliary).METHODS: In in vivo study, we investigated the effect of TMP on the secretion of pancreatic...
关键词：胰腺外分泌物 胆汁分泌物 川芎嗪 CAMP CGMP 药理作用 实验研究 
harmacokinetics of Tetramethylpyrazine Phosphate inHealthy and Blood Stasis Dogs in vivo
《Chinese Journal of Integrative Medicine》1996年第2期132-134,共3页蒋永培 文爱东 黄熙 臧益民 张雷华 
To test the hypotliesis of Syndrome and Treatment Pharmacokinetics (S-TPK ) , tlie authorsbeve stodied tlie pharmacokinetics of tetramethyrazine phosphate (TMPP) in healthy and blood stasis dogs byhigh performance liq...
关键词：traditional Chinese medicine TETRAMETHYLPYRAZINE blood stasis PHARMACOKINETICS highperformance liquid chromatography 
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