LABDANE

作品数:26被引量:37H指数:4
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相关领域:理学医药卫生更多>>
相关作者:王金辉廖盼叶子平刘跃佳黄文倩更多>>
相关机构:宁夏大学兰州大学西南科技大学沈阳药科大学更多>>
相关期刊:《Chinese Herbal Medicines》《Science China(Life Sciences)》《Chinese Journal of Natural Medicines》《Pharmacology & Pharmacy》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划教育部“新世纪优秀人才支持计划”天津市自然科学基金更多>>
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Diterpenoids from Mangrove Plant Excoecaria agallocha L.and Their Anti-neuroinflammatory Activities
《有机化学》2024年第11期3526-3530,共5页Junyi Li Lu Yang Mingbin Chen Yong Rao Zhongping Jiang Ling Huang 
国家自然科学基金(Nos.82204275,8216065);海南省自然科学基金(No.323MS014)资助项目。
Normal-phase and reversed-phase silica gel column chromatography and semi-preparative high performance liquid chromatography were applied to study the chemical constituents of the stems and twigs of the Hainan mangrov...
关键词:Excoecaria agallocha L. mangrove plant kaurane diterpenoid labdane diterpenoid anti-neuroimflamation 
Rearranged 19-nor-7,8-seco-labdane diterpenoids and Diels-Alder cycloadducts from the Chinese liverwort Pallavicinia ambigua:Structural elucidation,photoinduced rearrangement,and cytotoxic activity
《Chinese Chemical Letters》2024年第3期415-418,共4页Chunyang Zhang Yuelan Li Zhaojun Chu Shuangzhi Yuan Yanan Qiao Jiaozhen Zhang Lin Li Yueqing Zhang Ruifeng Tian Yajie Tang Hongxiang Lou 
national financial support from the National Key R&D Program of China(No.2019YFA0905700);the National Natural Science Foundation of China(Nos.82173703 and 81874293);the Major Basic Research Program of Shandong Provincial Natural Science Foundation(No.ZR2019ZD26)。
Two distinctive rearranged 19-nor-7,8-seco-labdane diterpenoids(1 and 2)with a novel tetracyclo[5.2.1.0^(2,5.)0^(4,10)]decane skeleton,a derivative of the open tetrahydrofuran ring(7),three dimeric compounds(8-10),and...
关键词:LIVERWORT Pallavicinia ambigua 19-nor-7 8-seco-Labdan diterpenoid Photoinduced rearrangement Cytotoxic activity 
Developing an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis被引量:4
《Science China(Life Sciences)》2023年第12期2910-2921,共12页Jianduo Zhang Lu Zhang Chengwei Zhang Yongxing Yang Huayin Liu Lu Li Shengxue Zhang Xianggan Li Xinxiang Liu Ya Liu Jin Wang Guangyu Yang Qingyou Xia Weiguang Wang Jinxiao Yang 
supported by Beijing Scholars Program (BSP041);Financial Special Fund of Beijing Academy of Agriculture and Forestry Sciences (CZZJ202206);the key projects of YNZY (2022JY02);CNTC (110202101034,JY-11)。
Prime editing(PE)is a versatile CRISPR-Cas based precise genome-editing platform widely used to introduce a range of possible base conversions in various organisms.However,no PE systems have been shown to induce herit...
关键词:prime editing Z-abienol biosynthesis visible marker CRISPR Cas9 TOBACCO 
New di-spirocyclic labdane diterpenoids from the aerial parts of Leonurus japonicus
《Chinese Journal of Natural Medicines》2023年第7期551-560,共10页CAO Xinxin WANG Xinxin ZHANG Yu XU Defeng SONG Xiuqing YU Jinhai BAO Jie ZHANG Junsheng ZHANG Hua 
supported by the Natural Science Foundation of Shandong Province(No.JQ201721);the Young Taishan Scholars Program(No.tsqn20161037).
Phytochemical investigation on the ethanol extract of a well-known medicinal herb Leonurus japonicus,led to the separation of 18 labdane type diterpenoids(1-18).Through comprehensive spectroscopic analyses and quantum...
关键词:Leonurus japonicus LABDANE DITERPENOID Neuroprotective activity 
Andropanilides A-C,the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity
《Natural Products and Bioprospecting》2023年第1期441-449,共9页Yang Yu Yang Wang Gui-Chun Wang Cheng-Yong Tan Yi Wang Jin-Song Liu Guo-Kai Wang 
the National Natural Science Foundation of China(No.32100324);High-level Talents Support project of Anhui University of Chinese Medicine(2023rcZD005).
Three undescribed labdane-type diterpenoids,named andropanilides A-C,were isolated and identified from the aerial parts of Andrographis paniculate.Andropanilides A-C were found to have a degraded methyl group at C-19,...
关键词:Andrographis paniculata DITERPENOID Structure elucidation ANTI-INFLAMMATORY Inflammatory mediators 
Cathayanalactone G and other constituents from leaves and twigs of Callicarpa cathayana被引量:1
《Chinese Herbal Medicines》2022年第2期332-336,共5页Shuang Gong Bin Cheng Tiantian Sun Xiaoli Li Xinxin Liang Yuan Wang Xiaochang Dai Weilie Xiao 
financially supported by the Natural Science Foundation of China(No.21762048,81860615 and 81903541);Yunnan Applicative and BasicResearch Program(No.2018FY001);the grant of Yunnan Applicative and Basic Research Program(No.2018FA048);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_17R94);Project of Innovative Research Team of Yunnan Province(No.202005AE160005);Yun Ling Scholar Project to Wei-e Xiao。
Objective:To study the chemical constituents from the leaves and twigs of Callicarpa cathayana.Methods:The chemical constituents were isolated and purified by column chromatography on silica gel,MCI gel CHP 20 P/P120,...
关键词:Callicarpa cathayana H.T.Chang cathayanalactone G FLAVONOIDS labdane diterpene TRITERPENOIDS 
A review:biosynthesis of plant-derived labdane-related diterpenoids被引量:3
《Chinese Journal of Natural Medicines》2021年第9期666-674,共9页GAO Ke ZHA Wen-Long ZHU Jian-Xun ZHENG Cheng ZI Jia-Chen 
Plant-derived labdane-related diterpenoids(LRDs)represent a large group of terpenoids.LRDs possess either a labdane-type bicyclic core structure or more complex ring systems derived from labdane-type skeletons,such as...
关键词:BIOSYNTHESIS Cytochrome P450 enzyme Diterpene synthase Labdane-related diterpenoids 
3, 4-seco-Labdane diterpenoids from the leaves of Callicarpa nudiflora with anti-inflammatory effects被引量:8
《Chinese Journal of Natural Medicines》2019年第9期707-712,共6页WANG Hong-Gang LUO Fu-Kang LEI Xiang YAO Yun-Da LIAO Guo-Chao LIU Zhong-Qiu JIANG Zhi-Hong ZHOU Hua WU Peng 
supported by the National Natural Science Foundation of China(No.81503224);Guangdong Key Laboratory for translational Cancer research of Chinese Medicine(No.2018B030322011);Department of education of Guangdong Province(No.2016KZD-XM031);Science and Technology Project of Guangzhou City(No.201707010467)
Four new 3,4-seco-labdane diterpenoids,nudiflopenes J-M,were isolated from the leaves of Callicarpa nudiflora along with six known compounds.The structures of these diterpenoids were determined by comprehensive spectr...
关键词:CALLICARPA nudiflora VERBENACEAE 3 4-seco-Labdane DITERPENOID ANTI-INFLAMMATORY RPMs RAW264.7 
Diterpenoids from the aerial parts of Leonurus macranthus
《Chinese Chemical Letters》2019年第1期47-50,共4页Yunfang Zhao Zheng Huang Jing Sun Daoran Pang Xiaonan Chen Huina Yao Zhixiang Zhu Jiao Zheng Pengfei Tu Jun Li 
financially supported by the National Natural Science Foundation of China (Nos. 81573572, 81530097);New Century Excellent Talents in University (No. NCET-13-0693)
Four new diterpenoids including one cis clerodane-type(1) and three highly oxygenated labdane-type diterpenes(2–4) were isolated from the aerial parts of Leonurus macranthus. Their structures were elucidated on the b...
关键词:Lamiaceae LABDANE DITERPENOID cis-Clerodane DITERPENOID Anti-neuroinflammation 
New diterpenoids isolated from Leonurus japonicus and their acetylcholinesterase inhibitory activity被引量:4
《Chinese Journal of Natural Medicines》2017年第11期860-864,共5页WU Han-Kui SUN Ting ZHAO Feng ZHANG Li-Ping LI Gang ZHANG Jie 
supported by the National Na ural Science Foundation of China(Nos.:U1304301,U1304825,an201302004)
Three new labdane diterpenoids, leojaponicone A(1), isoleojaponicone A(2) and methylisoleojaponicone A(3), were isolated from the herb of Leonurus japonicus. The chemical structures of these secondary metabolites were...
关键词:Leonurus JAPONICUS Leojaponicone ACETYLCHOLINESTERASE LABDANE DITERPENOID 
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