There is emerging evidence implicating glucagon-like peptide-1 (GLP-1) in reward, including palatable food reinforcement and alcohol-based reward circuitry. While recent findings suggest that mesolimbic structures, su...
The study of verbal behavior focuses on communicative functions of the speakers/producers as they affect the behavior of listeners/observers. Effects on the listener reinforce the speaker and the listener/observer ben...
A novel motor learning method is present based on the cooperation of the cerebellum and basal ganglia for the behavior learning of agent. The motor learning method derives from the principle of CNS and operant learnin...
AcknowledgementsThis study was supported by the National Basic Research Program grants from the Ministry of Science and Technology of China (No 2003CB515400 and No 2009CB522000), the National Science Fund for Distinguished Young Scholars from the National Natural Science Foundation of China (No 30425002) and the Chinese Academy of Sciences (No KSCXI/YW/R/68). We thank Aaron Ettenberg for helpful suggestions on runway behavior and Barry J Everitt for the heterogeneous chained schedule.
Aim: To evaluate the influence of an initial heroin experience under a modified two-chained training schedule on drug-seeking behavior after a long abstinence period. Methods: Rats were trained to respond for intr...
This work was supported by grants from the National Natural Science Foundation of China (No. 30470549);the National Basic Research Priorities Programme (973) of China (No.2006CBS00800)
Objective To investigate whether repeated morphine exposure or prolonged withdrawal could influence operant and spatial learning differentially. Methods Animals were chronically treated with morphine or subjected to m...
supported by the National Natural Science Foundation of China(Grant Nos.39770187&69835020);the Multidisciplinary Research Program of Chinese Academy of Sciences;the Major State Basic Research Program(G2000077800).
In visual operant conditioning of Drosophila at the flight simulator, only motor output of flies——yaw torque——is recorded, which is involved in the conditioning process. The current study used a newly-designed dat...
DGICYT PM 96/0047,Comunidad de Madrid and Plan Nacional Sobre Drogas(MN,FRF);National Institutes of Health grants AA 06420;AA 08459 from the National Institute on Alcohol Abuse and Alcoholism(GFK and AJR)
AIM:To study the potential role of dependence statuson CB_(1)-mediated blockade of ethanol self-administra-tion.METHODS:We examined the effects of thecannabinoid antagonist SR141716A(0,0.03,0.3,and 3 mg/kg)on pperant ...
Using the flight simulator system, the operant conditioned visual flight orientation behavior in Drosophila was studied. It was demonstrated that the visual learning performance is associated with age; flies learn mor...
Project supported by the National Natural Science Foundation of China.
Operant visual learning has been demonstrated in Drosophila melanogaster by using a flight simulator, with visual patterns as conditioned stimulus (CS) and heat as negative reinforcer (US). Learning acquisition increa...