grants from the National Natural Science Foundation of China(No.82074162,81903995);the Young Elite Scientists Sponsorship Program by CACM(No.CACM-2019-QNRC2-C10);Science and Technology Innovation Project of Putuo District Health System(No.ptkwws201902,ptkwws201908,ptkwws202009,ptkwws202107)and Research Project(No.2019307,2020308A);the One Hundred Talents(No.2022-RCLH-02)of Putuo Hospital,Shanghai University of Traditional Chinese Medicine。
The CTCF/cohesin complex regu- lates higher order chromatin structure by creating long-range chromatin loops and by insulating neighboring genes from each other. The lymphocyte antigen receptor loci have large numbers...