supported by the National Natural Science Foundation of China(32271545 and 31972030);Major Program of Haihe Laboratory of Synthetic Biology(22HHSWSS00016 and 22HHSWSS00003);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008-03 and TSBICIP-PTJJ-007-10);Youth Promotion Association of Chinese Academy of Sciences(CAS)(2021176);CAS Project for Young Scientists in Basic Research(YSBR-072)。