Β-SITOSTEROL

作品数：28被引量：161H指数：6
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相关领域：医药卫生更多>>
相关作者：李帅王素娟石建功杨永春薛震更多>>
相关机构：中国医学科学院北京协和医学院泸州医学院附属中医院中国药科大学黑龙江中医药大学更多>>
相关期刊：《Neural Regeneration Research》《Asian Pacific Journal of Tropical Medicine》《中药材》《中国中药杂志》更多>>
相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金广州市科技局资助项目更多>>
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Highβ-sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals
《Food Science and Human Wellness》2024年第5期2779-2789,共11页Jinyin Zhang Lu Huang Xiang Tang Miao Pan Xiaoli Ye Xuegang Li Hang Ma 
supported by Special Key project of Technology Innovation and Application Development in Chongqing(CSTC2021jscx-gksb-N0033,CSTB2021TIAD-KPX0085);Science Foundation of School of Life Sciences SWU(20212005425201);County-University Cooperation Innovation Funds of Southwest University(SZ202102).
β-Sitosterol-D-glucoside(β-SDG)is a phytosterol compound whose antitumor activity has been confirmed by previous studies.However,its suppression on breast cancer remains unclear.To that purpose,we isolatedβ-SDG fro...
关键词：β-Sitosterol-D-glucoside(β-SDG) Sweet potato Breast cancer Proteomic Metastasis 
Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis被引量：5
《Neural Regeneration Research》2024年第3期642-649,共8页Xiuling Tang Tao Yan Saiying Wang Qingqing Liu Qi Yang Yongqiang Zhang Yujiao Li Yumei Wu Shuibing Liu Yulong Ma Le Yang 
supported by the National Natural Science Foundation of China,Nos.82104158(to XT),31800887(to LY),31972902(to LY),82001422(to YL);China Postdoctoral Science Foundation,No.2020M683750(to LY);partially by Young Talent Fund of University Association for Science and Technology in Shaanxi Province of China,No.20200307(to LY).
β-Sitosterol is a type of phytosterol that occurs naturally in plants.Previous studies have shown that it has anti-oxidant,anti-hyperlipidemic,anti-inflammatory,immunomodulatory,and anti-tumor effects,but it is unkno...
关键词：APOPTOSIS blood-brain barrier Β-SITOSTEROL cerebral ischemia/reperfusion injury cholesterol overload cholesterol transport endoplasmic reticulum stress ischemic stroke molecular docking NPC1L1 
A network pharmacology- and transcriptomics-based investigation reveals an inhibitory role of β-sitosterol in glioma via the EGFR/MAPK signaling pathway
《Acta Biochimica et Biophysica Sinica》2024年第2期223-238,共16页Yufang Xie Zhijian Chen Shuang Li Meijuan Yan Wenjun He Li Li Junqiang Si Yan Wang Xinzhi Li Ketao Ma 
This work was supported by the grant from the National Natural Science Foundation of China(No.82260492).
Glioma is characterized by rapid cell proliferation,aggressive invasion,altered apoptosis and a poor prognosis.β-Sitosterol,a kind of phytosterol,has been shown to possess anticancer activities.Our current study aims...
关键词：Β-SITOSTEROL GLIOMA proliferation G2/M phase arrest apoptosis EGFR/MAPK signaling pathway 
Qualitative and quantitative analysis ofβ-sitosterol marker in virgin camellia oil and virgin olive oil被引量：2
《Food Quality and Safety》2023年第4期579-587,共9页李阳 吴旻谕 翟量 张辉 沈立荣 
This research was funded by the“Pioneer”and“Leading Goose”R&D Program of Zhejiang Province(No.2023C02044);Zhejiang Province Key Research and Development Program(No.2021C02032);Zhejiang Provincial Natural Science Foundation(No.LQ20C200013),China.
Camellia oil and olive oil with superior economic value are easily adulterated with other,cheaper oils.It is difficult to identify both oils by traditional methods because of their similar fatty acid profiles.In the p...
关键词：Β-SITOSTEROL virgin camellia oil(VCO) virgin olive oil(VOO) qualitative analysis quantitative analysis 
Determination ofβ-sitosterol in Plumbago zeylanica L.by HPLC-ELSD
《Medicinal Plant》2022年第3期6-8,共3页Hongyu ZHAO 
[Objectives]A method for the determination ofβ-sitosterol in Plumbago zeylanica L.was established and the content ofβ-sitosterol in different medicinal parts,different producing areas and different harvest periods w...
关键词：Plumbago zeylanica L. Β-SITOSTEROL CONTENT HPLC-ELSD method 
First Isolation and Confirmation of Sterol Based on β-sitosterol Skeleton from the Leaves of Podocarpusnagi Planted in Fujian, Preliminary in vitro Anticancer Activity and the Crystal Structure
《Chinese Journal of Structural Chemistry》2021年第5期653-658,531,共7页YANG Yang YONG Jian-Ping OLAGOKE Zacchaeus Olatunde LU Can-Zhong 
financially supported by the National Natural Science Foundation of China(21875252);Self-created Area Project of Major Science Technology Innovation Platform of Xiamen(3502ZCQ20171002)。
The crystal of(24 R)-3β,5α-dihydroxy-24-ethyl-5α-cholestan-6-one(1) was isolated from the leaves of P.nagi planted in Fujian for the first time with the same skeleton as 26,27-dinorcholest-5-en-3-β-ol(2) andβ-sit...
关键词：Podocarpusnagi crystal structure STEROLS ISOLATION anticancer evaluation 
β-sitosterol ameliorates influenza A virus-induced proinflammatory response and acute lung injury in mice by disrupting the cross-talk between RIG-I and IFN/STAT signaling被引量：24
《Acta Pharmacologica Sinica》2020年第9期1178-1196,共19页Bei-xian Zhou Jing Li Xiao-li Liang Xi-ping Pan Yan-bing Hao Pei-fang Xie Hai-ming Jiang Zi-feng Yang Nan-shan Zhong 
This study was funded by the National Natural Science Foundation of China(grant no.81873065);the Secondary Development Projects of Guangdong Famous and Excellent Traditional Chinese Patent Medicines(grant no.20174005);the Natural Science Foundation of Guangdong Province(grant no.2018A030310172);the China Postdoctoral Science Foundation(grant nos.2017M622652 and 2019M652987).
β-Sitosterol(24-ethyl-5-cholestene-3-ol)is a common phytosterol Chinese medical plants that has been shown to possess antioxidant and anti-inflammatory activity.In this study we investigated the effects ofβ-sitoster...
关键词：influenza A virus Β-SITOSTEROL RIG-I IFN-Β ANTI-INFLAMMATORY acute lung injury 
Response surface methodology-based optimization of ultrasound-assisted extraction of β-sitosterol and lupeol from Astragalus atropilosus(roots) and validation by HPTLC method被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2020年第6期281-292,共12页Perwez Alam Nasir A.Siddiqui Ali S.Alqahtani Anzarul Haque Omer A.Basudan Saleh I.Alqasoumi M.U.Khan 
the Researchers Supporting Project Number(RSP-2019/132),King Saud University,Riyadh,Kingdom of Saudi Arabia.
Objective:To optimize the ultrasonication method for efficient extraction ofβ-sitosterol and lupeol from the roots of Astragalus atropilosus using Box-Behnken design of response surface methodology(RSM),and its valid...
关键词：Β-SITOSTEROL LUPEOL Box-Behnken design ASTRAGALUS High performance thin layer CHROMATOGRAPHY 
Development of a novel electrospun nanofibrous delivery system for poorly water-soluble β-sitosterol被引量：1
《Asian Journal of Pharmaceutical Sciences》2016年第4期500-506,共7页Urve Paaver Ivo Laidmae Hélder A.Santos Jouko Yliruusi Jaan Aruvali Karin Kogermann Jyrki Heinamaki 
This study is supported by the European Social Fund’s Doctoral Studies and Internationalisation Programme DoRa.The work is part of the ETF Grant Project No.ETF7980 and IUT-34-18 Project.Kerly Kustavus is kindly acknowledged for drawing the chemical structures of plant sterols.Dr.Korbinian Löbmann is kindly acknowledged for providing the Mercury files for the theoretical XRPD pattern calculations.Dr.H.A.Santos acknowledges financial support from the Academy of Finland(Decision No.252215).
Electrospinning was used as a novel technique for fabricating polymeric nanofibers of a serum cholesterol lowering and poorly water-soluble plant sterol, β-sitosterol. Chitosan was used as a stabilizer/carrier polyme...
关键词：ELECTROSPINNING Plant sterol Β-SITOSTEROL NANOFIBERS Solid-state properties DISSOLUTION 
Determination of β-sitosterol Content in Ethnodrug Guoshangye被引量：1
《Agricultural Science & Technology》2015年第11期2546-2548,共3页马四补 张应蓉 屈相玲 靳凤云 
Supported by Traditional Chinese Medicine and Ethnic Minority Medicine Technique Research Subject of Guizhou Administrative Bureau of TCM(QZYY2012-34);贵州省中医药管理局中医药,民族医药科学技术研究课题(QZYY2012-34)
[Objective] The contents of β-sitosteml in Guoshangye from different habi- tats were determined. [Metlmd] UPLC-ELSD was adopted to determine the contents of β-sitosteml in Guoshangye from different habitats, in whic...
关键词：Β-SITOSTEROL Ethnodrug Guoshanye DETERMINATION 
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