MYCOBACTERIUM

作品数：219被引量：348H指数：9
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  • 期刊=Biomedical and Environmental Sciencesx
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Characterization of Mutations in Genes Related to Rifampicin and Isoniazid Resistance in Multidrug-resistant Mycobacterium tuberculosis Strains from Hangzhou,China
《Biomedical and Environmental Sciences》2023年第9期869-873,共5页HUANG Yin Yan XIE Li WU Yi Fei JIA Qing Jun CHENG Qing Lin LI Qing Chun AI Li Yun BAI Xue Xin 
supported by the Hangzhou Medical Health Science and Technology Project [A20220614];Hangzhou Medical Health Science and Technology Project [A20200788];Hangzhou Medical Health Science and Technology Project [A20220558];Zhejiang General Research Project on Medical Health and Science Technology Plan [2021KY949];Public Welfare Technology Research Program in Zhejiang Province [LGF21H190002];Hangzhou Agricultural and Social Development Research Guide Project [20220919Y060]。
Tuberculosis(TB),caused by the Mycobacterium tuberculosis complex(MTBC),is the 13^(th)leading cause of death and the second leading cause of infectious killer after COVID-19(above HIV and AIDS),according to the World ...
关键词：TUBERCULOSIS DEATH MYCOBACTERIUM 
Evaluation of Microsphere-based xMAP Test for gyrA Mutation Identification in Mycobacterium Tuberculosis
《Biomedical and Environmental Sciences》2023年第4期384-387,共4页OU Xi Chao ZHAO Bing SONG Ze Xuan PEI Shao Jun WANG Sheng Fen HE Wen Cong LIU Chun Fa LIU Dong Xin XING Rui Da XIA Hui ZHAO Yan Lin 
funded by the National Key R&D Program [2022YFC2305200];China CDC-Tuberculosis Control and Prevention Project [228711]。
Drug-resistant(DR) tuberculosis(TB) is a growing threat to public health[1]. Fluoroquinolone(FQ) antibiotics have long been used as anti-tuberculosis drugs, and their widespread application has led to the development ...
关键词：TUBERCULOSIS drugs MYCOBACTERIUM 
Evaluation of Multidrug Resistant Loop-mediated Isothermal Amplification Assay for Detecting the Drug Resistance of Mycobacterium tuberculosis被引量：5
《Biomedical and Environmental Sciences》2021年第8期616-622,共7页LIU Chun Fa SONG Yi Meng HE Ping LIU Dong Xin HE Wen Cong LI Yan Ming ZHAO Yan Lin 
the Chinese Center for Disease Control and Prevention project[59911905 and 59911916].
Objective To evaluate multidrug resistant loop-mediated isothermal amplification(MDR-LAMP)assay for the early diagnosis of multidrug-resistant tuberculosis and to compare the mutation patterns associated with the rpoB...
关键词：MDR-LAMP MYCOBACTERIUM TUBERCULOSIS DIAGNOSTIC method 
Immunogenicity of Whole Mycobacterium intracellulare Proteins and Fingding on the Cross-Reactive Proteins between M.intracellulare and M.tuberculosis被引量：1
《Biomedical and Environmental Sciences》2021年第7期528-539,共12页XIAO Shi Qi XU Da DUAN Hong Yang FAN Xue Ting LI Gui Lian ZHANG Wen LI Ma Chao HAN Na LI Xin Yao LI Na ZHAO Li lan ZHAO Xiu Qin WAN Kang Lin LIU Hai Can FENG Wen Hai 
supported by National Science and Technology Major Project of China[2018ZX10731301-002]。
Objectives To evaluate the immunogenicity of Mycobacterium intracellulare proteins and determine the cross-reactive proteins between M.intracellulare and M.tuberculosis.Methods Protein extracts from M.intracellulare w...
关键词：Mycobacterium intracellulare Mycobacterium tuberculosis Cross-reactive immune response Vaccine ANTIGEN 
Immunological Evaluation of a Novel Mycobacterium tuberculosis Antigen Rv0674被引量：5
《Biomedical and Environmental Sciences》2019年第6期427-437,共11页XIAO Tong Yang LIU Hai Can LI Xiao Qin HUANG Ming Xiang LI Gui Lian LI Na YAN Yu Han LUO Qiao WANG Xue Zhi LI Ma Chao WAN Kang Lin 
National Science and Technology Major Project of China [2018ZX10731301-002]
Objective This study aimed to characterize the diagnostic and vaccine potential of a novel Mycobacterium tuberculosisantigen Rv0674. Methods To evaluate thediagnostic potential and antigenicity of Rv0674, IgG was eval...
关键词：ANTIGEN IMMUNOLOGIC diagnosis MYCOBACTERIUM TUBERCULOSIS Rv0674 VACCINE 
Activities of Biapenem against Mycobacterium tuberculosis in Macrophages and Mice被引量：1
《Biomedical and Environmental Sciences》2019年第4期235-241,共7页GUO Zhen Yong ZHAO Wei Jie ZHENG Mei Qin LIU Shuo YAN Chen Xia LI Peng XU Shao Fa 
supported by the Beijing Medical Award Foundation [YJHYXKYJJ-104]
Objective To assess the activities of biapenem against multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis. Methods Biapenem/clavulanate(BP/CL) was evaluated for in vitro activity against Myc...
关键词：BIAPENEM CLAVULANATE MULTIDRUG resistant EXTENSIVE DRUG-RESISTANT MYCOBACTERIUM tuberculosis Activity Macrophage Synergy 
Comparison of Xpert MTB/RIF, Real Amp, and CPA Tests in Detecting Mycobacterium tuberculosis被引量：11
《Biomedical and Environmental Sciences》2019年第3期215-219,共5页OU Xi Chao LI Hui LIU Dong Xin XIA Hui MA Xiao Guang WANG Shao Hua WANG Sheng Fen ZHU Yan Kun ZHAO Bing ZHAO Yan Lin 
supported by the National Science and Technology Major Project [2018ZX10103001];the National Natural Science Foundation of China [8161101571]
Today, tuberculosis (TB) remains a global public health threat associated with significantly high rates of morbidity and mortality. The World Health Organization's (WHO) Global Tuberculosis Report 2018[1] has reported...
关键词：COMPARISON Detecting MYCOBACTERIUM TUBERCULOSIS Xpert MTB/RIF 
First Report in China on the Identification and Drug Sensitivity of Mycobacterium elephantis Isolated from the Milk of a Cow with Mastitis被引量：2
《Biomedical and Environmental Sciences》2017年第7期501-507,共7页JI Ling Yun XU Dong Lei YIN Shu Peng LIU Hai Can LI Gui Lian JIANG Yi WEI Jian Hao ZENG Hao LOU Yong Liang LYU Jian Xin WAN Kang Lin 
supported by the project 81401647 of Natural Science Foundation of China;Project 2014SKLID104 of State Key Laboratory for Infectious Diseases Prevention and Control;projects 16411967900 of Science and Technology Commission of Shanghai Municipality
Objective In this study, milk from a cow with mastitis was analyzed to determine the presence of mycobacterial infection. Milk quality and security problems pertaining to the safe consumption of dairy products were al...
关键词：Key words： Non-tuberculosis mycobacterium Mycobacterium elephantis MILK Cow mastitis 
Comparing the Genotype and Drug Susceptibilities between Mycobacterium avium and Mycobacterium intracellulare in China被引量：5
《Biomedical and Environmental Sciences》2017年第7期517-525,共9页ZHENG Hui Wen PANG Yu HE Guang Xue SONG Yuan Yuan ZHAO Yan Lin 
supported by a grant from the National Basic Research Program of China 2014CB744403;the National Science and Technology Major Project 2014ZX100030002
Objective Mycobacterium avium （M. avium） and Mycobacterium intracellulare （M. intracellulare） are the major causative agents of nontuberculous mycobacteria （NTM）-related pulmonary infections. However, little is ...
关键词：Nontuberculous mycobacterium  Phenotype GENOTYPE SUSCEPTIBILITY Resistance 
Multicenter Evaluation of the Molecular Line Probe Assay for Multidrug Resistant Mycobacterium Tuberculosis Detection in China被引量：13
《Biomedical and Environmental Sciences》2015年第6期464-467,共4页LI Qiang DONG Hai Yan PANG Yu XIA Hui OU Xi Chao ZHANG Zhi Ying LI Jun Chen ZHANG Jian Kang HUAN Shi Tong CHIN Daniel P KAM Kai Man ZHAO Yan Lin 
supported by Bill&Melinda Gates Foundation Tuberculosis Prevention and Control Project(2009-04-01)
In order to evaluate the performance of a molecular Hain line probe assay （Hain LPA） for rapid detection of rifampicin and isoniazid resistance of Mycobocterium tuberculosis in China, 1612 smear positive patients we...
关键词：Mycobacterium Probe tuberculosis detecting sequenced phenotypic likely inconsistent specimen elsewhere 
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