OCTAMER

作品数:17被引量:32H指数:4
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相关领域:医药卫生更多>>
相关作者:黄健清郭亮杨玉清李建民姚宏更多>>
相关机构:广州医学院附属肿瘤医院太原市人民医院太原钢铁(集团)有限公司总医院山西省肿瘤医院更多>>
相关期刊:《Journal of Integrative Agriculture》《World Journal of Clinical Oncology》《南方医科大学学报》《Science China(Life Sciences)》更多>>
相关基金:国家自然科学基金中国博士后科学基金上海市浦江人才计划项目上海市自然科学基金更多>>
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Role of octamer transcription factor 4 in proliferation,migration,drug sensitivity,and stemness maintenance of pancreatic cancer cells
《World Journal of Clinical Oncology》2025年第3期83-94,共12页Xue-Ying Shi Xi-Lan Wang Jin Zhao Shi-Hai Yang Cheng-Hai Zhang 
Supported by Inner Mongolia Natural Science Foundation and the 3rd Affiliated of Inner Medical University,No.2021MS08067.
BACKGROUND Pancreatic cancer(PC)is one of the most aggressive malignancies characterized by rapid progression and poor prognosis.The involvement of cancer stem cells(CSCs)and Octamer transcription factor 4(OCT4)in PC ...
关键词:Pancreatic cancer Octamer transcription factor 4 Cancer stem cells PROLIFERATION Drug sensitivity STEMNESS 
Anillin actin-binding protein expression correlates with poor prognosis for prostate cancer patients
《Asian Journal of Urology》2024年第4期569-574,共6页Shinichiro Yamamoto Daisuke Obinata Kenichi Takayama Daigo Funakoshi Kyoko Fujiwara Makoto Hara Satoru Takahashi Satoshi Inoue 
supported by funding from Takeda Science Foundation,and JSPS KAKENHI(grant numbers JP19H03793 to Obinata D,JP20K07350 to Takayama K,JP19K09740 to Takahashi S,JP20K07875 to Hara M,and JP20K21667 and JP21H04829 to Inoue S).
Objective:Octamer transcription factor 1(OCT1),a transcription factor that interacts with androgen receptor,is involved in prostate cancer(PCa)progression.The OCT1 target gene,Anillin actin-binding protein(ANLN),is hi...
关键词:Prostatecancer Androgenreceptor Octamer transcriptionfactor1 Anillin actin-binding protein 
OCT4’s role and mechanism underlying oral squamous cell carcinoma
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第9期796-806,共11页Yuwei DAI Ziqiong WU Yitong CHEN Xinjian YE Chaowei WANG Huiyong ZHU 
supported by the Health Commission of Zhejiang Province(No.2022RC027),China。
Oral squamous cell carcinoma(OSCC),a common malignancy of the head and neck,ranks sixth worldwide in terms of cancers with the most negative impact,owing to tumor relapse rates,cervical lymphnode metastasis,and the la...
关键词:Cancer stem cell(CSC) Octamer-binding transcription factor 4(OCT4) Oral squamous cell carcinoma(OSCC) Prognosis Signaling pathway 
Leukemia Inhibitory Factor Enhanced the Developmental and Implantation Compatibility of Mouse Embryos in Co-culture with Human Endometrial Epithelial Cells被引量:1
《Reproductive and Developmental Medicine》2021年第4期199-205,共7页Ali Hosseini Bahar Movaghar Showra Amani Abkenari Hassan Nazari Mehrdad Bakhtiyari 
Objective:Among the variousin vitro embryo culture systems,co-culture has demonstrated remarkable effects in pre-implantation embryo development owing to the production of embryo-nourishing factors.Nevertheless,little...
关键词:Caudal Type Homeobox 2 Embryo Development Leukemia Inhibitory Factor Octamer-Binding Transcription Factor 4 
Mutational Analysis of OCT4+ and OCT4− Circulating Tumour Cells by Single Cell Whole Exome Sequencing in Stage I Non-Small Cell Lung Cancer Patients被引量:1
《Journal of Shanghai Jiaotong university(Science)》2021年第1期40-46,共7页YAN Bo FU Shijie CHANG Yuanyuan GU Aiqin DONG Qianggang LI Rong 
the National Natural Science Foundation of China(No.81773273)。
Circulating tumour cells(CTCs)were enriched in the peripheral blood of four patients with Stage I non-small cell lung cancer(NSCLC).Octamer-binding transcription factor-4 positive(OCT4+)and negative(OCT4−)CTCs were id...
关键词:non-small cell lung cancer(NSCLC) octamer-binding transcription factor-4(OCT4) circulating tumour cells(CTCs) whole exome sequencing(WES) 
Significant association between IL-18 and OCT4 gene polymorphisms in susceptibility and clinical characteristics of prostate cancer被引量:2
《Oncology and Translational Medicine》2019年第3期123-130,共8页Shaojun Nong Yangbo Guan Zhiwei Wang Zhongqing Wei Yueping Zhang Jian Ni Chongsheng He Limin Ma Shujun Zhou Wenguang Li 
Supported by grants from the China Postdoctoral Science Foundation(No.2014M139951);the Science and Technology Project of Nantong,Jiangsu Province(No.MS22016043)
Objective Recent studies have shown abnormal expression of octamer-binding transcription factor 4(OCT4) and interleukin-18(IL-18) to be related to cancer. However, the molecular mechanisms by which the IL-18 and OCT4 ...
关键词:clinical characteristics interleukin-18(IL-18) octamer-binding TRANSCRIPTION factor 4(OCT4) polymorphism prostate cancer 
Cylindrical vector beam-excited frequency-tunable second harmonic generation in a plasmonic octamer被引量:6
《Photonics Research》2018年第3期157-161,共5页FAJUN XIAO WUYUN SHANG WEIREN ZHU LEI HAN MALIN PREMARATNE TING MEI JIANLIN ZHAO 
National Key R&D Program of China(2017YFA0303800);National Natural Science Foundation of China(NSFC)(11634010,51777168,61377035,61675170,61675171,61701303);Australian Research Council(ARC)(DP140100883);Natural Science Basic Research Plan in Shaanxi Province,China(2017JM6022);Fundamental Research Funds for the Central Universities,China(3102017zy017);Natural Science Foundation of Shanghai,China(17ZR1414300);Shanghai Pujiang Program,China(17PJ1404100)
We report a method to tune the second harmonic generation(SHG) frequency of a metallic octamer by employing cylindrical vector beams as the excitation. Our method exploits the ability to spatially match the polarizati...
关键词:SHG Cylindrical vector beam-excited frequency-tunable second harmonic generation in a plasmonic octamer 
Investigation of L/D-threonine substituted L-serine octamer ions by mass spectrometry and infrared photodissociation spectroscopy被引量:1
《Chinese Chemical Letters》2017年第3期537-540,共4页Juan Ren Yi-Yun Wang Ru-Xia Fenga Xiang-Lei Kong 
Financial support from the National Natural Science Foundation of China(No.21475065)
Threonine-substituted serine octamer ions were generated by electrospray ionization(ESI) and investigated by mass spectrometry and infrared photodissociation(IRPD) spectroscopy. IRPD spectra of[L-Ser_7+ L/D-Thr_1...
关键词:IRPD spectroscopy Threonine Serine octamer Chiral differentiation Mass spectrometry 
Methylation profile of bovine Oct4 gene coding region in relation to three germ layers被引量:4
《Journal of Integrative Agriculture》2016年第3期618-628,共11页ZHOU Xin-yu LIU Liang-liang JIA Wen-chao PAN Chuan-ying 
supported by the Natural Science Foundation of Shaanxi Province, China (2014JQ3104);the National Natural Science Foundation of China (31000655);China Postdoctoral Science Foundation funded project (2014M560809)
Previous studies have shown that octamer-binding transcription factor 4(Oct4) plays a significant role in early embryonic development of mammalian animals, and different Oct4 expression levels induce multi-lineage d...
关键词:bovine DNA methylation octamer-binding transcription factor 4(Oct4) exon germ layer 
Octamer 4基因在非小细胞肺癌中的表达及临床意义
《中国药物与临床》2014年第10期1332-1335,共4页杨玉清 姚宏 白家璐 魏俊燕 郭亮 王菲 李媛 李建民 
太原钢铁(集团)有限公司总医院科研课题(2013-8)
目的检测Octamer 4(Oct-4)基因在非小细胞肺癌(NSCLC)中的表达,探讨Oct-4在NSCLC发生、发展中的作用。方法采用流式细胞仪分选出肺癌细胞系A549中Oct-4+及Oct-4-的细胞群,用免疫荧光法检测分选后的细胞亚群中CD133的表达情况;采用体外...
关键词: 非小细胞肺 干细胞 OCT-4 
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