云南高校图书馆联盟文献共享服务平台- OX

OX: 作品数：824被引量：2137H指数：18; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：祝社民陈友存刘光祥沈岳松眭国荣更多>>; 相关机构：中国科学院中国科学院大学浙江大学南京工业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>

Correlations of vancomycin trough concentration and its efficacy and toxicity in patients in the intensive care unit: 《World Journal of Clinical Cases》2025年第16期18-28,共11页Teng Guo Li-Ying Du Ming-Feng Liu Xia-Jin Zhou Xin-Ran Chen; Supported by the Key Project Plan of Health and Medical Science Research in Hebei Provincial Health Commission,No.20190745.; BACKGROUND Plasma concentration monitoring is crucial for optimizing vancomycin use,particularly in patients in the intensive care unit(ICU).However,the reference interval for vancomycin plasma concentration remains u...; 关键词：VANCOMYCIN Therapeutic drug monitoring Intensive care unit Trough concentration Methicillin-resistant Staphylococcus aureus infection Area under the curve

Processing-induced reduction in dianthrones content and toxicity of Polygonum multiflorum:Insights from ultra-high performance liquid chromatography triple quadrupole mass spectrometry analysis and toxicological assessment: 《Animal Models and Experimental Medicine》2025年第4期685-695,共11页Wan-Fang Li Ying Wang Cai-Xia Qiu Jie Li Jie Bao Jian-Bo Yang Hong-Tao Jin; National Natural Science Foundation of China,Grant/Award Number:81973476;Chinese Society of Toxicology,Grant/Award Number:CST2021CT101。; Background:Polygonum multiflorum-induced liver injury(PM-DILI)has significantly hindered its clinical application and development.Methods:This study investigates the variation in content and toxicity of dian-thrones,t...; 关键词：dianthrones HEPATOTOXICITY Polygonum multiflorum Thunb. ultra-high performance liquid chromatography triple quadrupole mass spectrometry(UHPLC-QQQ-MS/MS) zebrafish embryos

Photochemical properties and toxicity of fluoroquinolone antibiotics impacted by complexation with metal ions in different pH solutions: 《Journal of Environmental Sciences》2025年第4期149-158,共10页Shengkai Cao Peng Zhang Heming Song Linke Ge Junfeng Niu; supported by the National Natural Science Foundation of China(Nos.21976045 and 22076112);China Scholarship Council(CSC)Scholarship(Nos.202208610125 and 202308610123);Shaanxi Key Laboratory of Environmental Monitoring and Forewarning of Trace Pollutants(No.SHJKFJJ202318);the Key Research and Development Program of Shaanxi Province(No.2024SF-YBXM-567).; Acid-base dissociable antibiotic-metal complexes are known to be emerging contaminants in the aquatic environments.However,little information is available on the photochemical properties and toxicity of these complex ...; 关键词：FLUOROQUINOLONE Photochemical properties Metal coordination Spectral analysis TOXICITY

Interfacial Ru nanoclusters in tandem with single atoms on oxygen-vacancy regulated CeO_(2)for anion exchange membrane seawater-splitting: 《Journal of Energy Chemistry》2025年第3期618-627,共10页Yue Wang Jing Li Pengfei Yang Hongdong Li Guangrui Xu Yunmei Du Caixia Li Wei Jin Tianyi Ma Zexing Wu Lei Wang; funding support from the National Natural Science Foundation of China(52371227;22002068;52272222,and 52072197);the Taishan Scholar Young Talent Program(tsqn201909114);the Shandong Province“Double-Hundred Talent Plan”(WST2020003);the Youth Innovation and Technology Foundation of Shandong Higher Education Institutions,China(2019KJC004);the Outstanding Youth Foundation of Shandong Province,China(ZR2019JQ14);the Major Basic Research Program of Natural Science Foundation of Shandong Province under Grant No.ZR2020ZD09;the Major Scientific and Technological Innovation Project(2019JZZY020405);the University Youth Innovation Team of Shandong Province(202201010318);the Youth Innovation Team Development Program of Shandong Higher Education Institutions(2022KJ155)。; A hydrogen spillover-bridged water dissociation/hydrogen formation could concurrently promote Volmer/Tafel process and improve the efficiency of hydrogen evolution reaction(HER)under alkaline conditions.However,it is ...; 关键词：ELECTROCATALYST CeO_(2) RU Oxygen vacancy Hydrogen evolution reaction

Targeting LINC070974 inhibits lung adenocarcinoma cell proliferation and progression by interacting with Y-box binding protein 1: 《Acta Biochimica et Biophysica Sinica》2025年第2期182-194,共13页Lin Liu Pengfei Gong Xueling Li Li Zhang Jiale Niu Jinhui Zhu Ziwei Wang Xingwang Long Tenghui Cao Yewen Liu Ganglin Wang Tingming Fu Liang Sun Wei Li; supported by the grants from the National Natural Science Foundation of China(Nos.81970753 and 31970636);the China Postdoctoral Science Foundation(No.2022M721989);the Wenzhou Science and Technology Bureau Foundation(No.ZY2021011).; Non-small cell lung cancer(NSCLC)is the leading cause of cancer-related mortality worldwide.Increasing evidence suggests that long noncoding RNAs play crucial roles in lung cancer pathogenesis.We previously identified...; 关键词：LINC070974 non-small cell lung cancer Y-box binding protein 1 cyclinD1 nebulized inhalation

基于BOPPPS教学模型的中职英语混合式教学流程设计——以“Ding Butchers an ox”一课为例: 《安徽教育科研》2025年第6期32-34,80,共4页李珍席君; 中职英语阅读课是拓宽知识、了解世界文化的素质教育课程,兼有工具性和人文性,根据《中等职业学校英语课程标准》,为解决存在的问题,本文提出“分”层施教精准教学、“析”解语言智慧课堂、“混”合案例资源拓展、“合”作任务互助激励...; 关键词：BOPPPS教学模型互动学习设计策略

长链非编码RNA lnc-Cox2在类风湿性关节炎发病中的作用: 《解剖科学进展》2025年第1期103-106,共4页宋强; 辽宁省科技攻关项目(2013225021)。; 目的观察长链非编码RNA lnc-Cox2对成纤维细胞样滑膜细胞(FLS)增殖、凋亡的影响,并探讨其诱发类风湿关节炎(RA)的发病机制。方法首先采用实时荧光聚合酶链反应法(RT-PCR)检测RA患者和健康志愿者血浆中lnc-Cox2和TNF-α水平;在RA-FLS...; 关键词：人类风湿关节炎长链非编码RNA lnc-Cox2 肿瘤坏死因子成纤维细胞样滑膜细胞

AI-assisted identification of a novel Orthopoxvirus inhibitor targeting F13: 《Biosafety and Health》2025年第1期33-37,共5页Junwen Luan Annan Ming Wenbo Zhao Liyuan Zhang Leiliang Zhanag; supported by the National Natural Science Foundation of China(82272306 and 82072270);the Taishan Scholars Program(tstp20221142).; Treatment of mpox virus(MPxV)is crucial for public health.However,research into drugs for MPxV has fallen behind,particularly in anticipation of sudden outbreaks.This study aimed to identify new inhibitors of Orthopox...; 关键词：Mpox mpox virus (MPXV) F13 Tecovirimat Artificial intelligence(Al)

A review on global spatial distribution,sources and toxicity of perfluoroalkyl acid and prospect in the cryosphere: 《Journal of Mountain Science》2025年第1期167-183,共17页LI Bowen Du Wentao KANG Shichang CHEN Jizu JIANG Youyan YIN Lichen LU Changsheng LIU Hongyi; supported by the Gansu Provincial Science and Technology Program(22ZD6FA005);West Light Foundation of The Chinese Academy of Sciences(xbzg-zdsys-202306);Science Fund for Creative Research Groups of Gansu Province(Grant No.23JRRA567);Taishan Scholars Program of Shandong Province(No.tsqn202312158);Key Research and Development Program of Gansu Province(22YF7FA041)。; Perfluoroalkyl acid analogs(PFAAs)are a class of chemically stable environmentally persistent organic pollutants(POPs)that are difficult to degrade and have a strong capacity to accumulate in the human body.PFAAs have...; 关键词：Perfluoroalkyl acid CRYOSPHERE Physiological toxicity Analytical method Removal method

Non-targeted screening and toxicity study of safety risk substances in facial skincare products:Molecular networking and computational toxicology strategy: 《Journal of Dermatologic Science and Cosmetic Technology》2024年第4期26-37,共12页Dong Guo Yaxiong Liu Jingwen Liang Yayang Huang Yangjie Li Jihui Fang Sheng Yin; supported by the Scientific and technological innovation project of Guangdong Provincial Drug Administration(ZA20230069,2024ZDZ04);the Science and Technology Plan Project of Guangdong Provincial(2023A1111120025).; Background:Risk substances in cosmetics have long been associated with adverse reactions.However,as risk substances become more concealed and diversified,conventional targeted analysis methods are no longer sufficient...; 关键词：Risk substances Non-targeted screening Molecular networking technology Computational toxicology

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

OX

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

OX

检索结果分析

下载全文

用户登录

高级检索检索式检索